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Effect of Combined Aspirin and Extended-Release...
Journal article

Effect of Combined Aspirin and Extended-Release Dipyridamole Versus Clopidogrel on Functional Outcome and Recurrence in Acute, Mild Ischemic Stroke

Abstract

BACKGROUND AND PURPOSE: Long-term antiplatelet therapy is effective at reducing recurrence after ischemic stroke. However, the relative safety and efficacy of combined aspirin-dipyridamole or clopidogrel are not known in patients with acute ischemic stroke. METHODS: The factorial PRoFESS secondary prevention trial assessed antiplatelet and blood pressure-lowering strategies in 20,332 patients, 1360 of whom were randomized within 72 hours of …

Authors

Bath PMW; Cotton D; Martin RH; Palesch Y; Yusuf S; Sacco R; Diener H-C; Estol C; Roberts R

Journal

Stroke, Vol. 41, No. 4, pp. 732–738

Publisher

Wolters Kluwer

Publication Date

April 2010

DOI

10.1161/strokeaha.109.564906

ISSN

0039-2499