Association of Minimal Clinically Important Difference With Infarct Volume in Clinical Poststroke Outcomes.

Abstract

BACKGROUND: Infarct volume is an imaging biomarker of ischemic tissue injury strongly correlated with poststroke outcomes and reperfusion benefit. We aimed to evaluate the follow-up infarct volume (FIV) difference corresponding to a 1%, 5%, and 10% increase in probability of excellent functional outcomes after intravenous thrombolysis. METHODS: Data are from the AcT trial (Alteplase Compared to Tenecteplase in Patients With Acute Ischemic …

Authors

Pensato U; Ospel JM; Zhang J; Barakhanov K; Tanaka K; Bala F; Kaveeta C; Kim D; Shamy M; Horn M

Journal

Journal of the American Heart Association, Vol. 14, No. 21,

Publisher

Wolters Kluwer

Publication Date

November 4, 2025

DOI

10.1161/jaha.125.044246

ISSN

2047-9980

Associated Experts

Luciana Catanese

Associate Professor, Faculty of Health Sciences

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