AXONAL TRANSPORT IN NIGRO‐STRIATAL AND NIGRO‐THALAMIC NEURONS: EFFECTS OF MEDIAL FOREBRAIN BUNDLE LESIONS AND 6‐HYDROXYDOPAMINE1

Abstract —Axonal transport was studied in two efferent projections of the substantia nigra : (1) the nigro‐striatal system; and (2) the nigro‐thalamic system. [ 14 C]leucine was injected stereotaxically into the left substantia nigra of rats. At various intervals thereafter significant amounts of [ 14 C]protein were found in the midbrain (which surrounded the injection site), hypothalamus, thalamus and corpus striatum on the injected side of …