Effects of schizophrenia and prefrontal leukotomy on movement preparation and generation

The purpose of this study was to investigate the ability of leukotomized and unleukotomized schizophrenic patients to use advance information in the process of movement preparation. Subjects participated in an aiming task in which movements could be defined on the basis of hand used to perform the task, and distance travelled to the target. Subjects were provided with full, partial, or no prior information about the upcoming movement by either …