Journal article
Comparison of Fondaparinux and Enoxaparin in Acute Coronary Syndromes
Abstract
BACKGROUND: The combined use of anticoagulants, antiplatelet agents, and invasive coronary procedures reduces ischemic coronary events but also increases bleeding in patients with acute coronary syndromes. We therefore assessed whether fondaparinux would preserve the anti-ischemic benefits of enoxaparin while reducing bleeding.
METHODS: We randomly assigned 20,078 patients with acute coronary syndromes to receive either fondaparinux (2.5 mg …
Authors
Yusuf S; Mehta SR; Chrolavicius S; Afzal R; Pogue J; Granger CB; Budaj A; Peters RJG; Bassand J-P; Wallentin L
Journal
New England Journal of Medicine, Vol. 354, No. 14, pp. 1464–1476
Publisher
Massachusetts Medical Society
Publication Date
April 6, 2006
DOI
10.1056/nejmoa055443
ISSN
0028-4793