Sirolimus Concept

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A phase I trial of ANG1/2-Tie2 inhibitor trebaninib (AMG386) and temsirolimus in advanced solid tumors (PJC008/NCI♯9041) Journal Articles
A phase II clinical and pharmacodynamic study of temsirolimus in advanced neuroendocrine carcinomas Conferences
A phase Ib combination study of RO4929097, a gamma-secretase inhibitor, and temsirolimus in patients with advanced solid tumors Journal Articles
An international expanded-access programme of everolimus: Addressing safety and efficacy in patients with metastatic renal cell carcinoma who progress after initial vascular endothelial growth factor receptor-tyrosine kinase inhibitor therapy Journal Articles
Autologous, lentivirus‐modified, T‐rapa cell “micropharmacies” for lysosomal storage disorders Journal Articles
CCI-779 Wyeth. Journal Articles
Characterisation of the lung toxicity of the cell cycle inhibitor temsirolimus Journal Articles
Clinical and toxicity predictors of response and progression to temsirolimus in women with recurrent or metastatic endometrial cancer Journal Articles
Combined mTOR Inhibition and OX40 Agonism Enhances CD8+ T Cell Memory and Protective Immunity Produced by Recombinant Adenovirus Vaccines Journal Articles
Combined mTOR inhibition and OX40 agonism enhances CD8(+) T cell memory and protective immunity produced by recombinant adenovirus vaccines. Journal Articles
Defining vascular anomaly phenotypes in children based on a systematic literature search: A critical step in developing a single severity score for interventional clinical trials Journal Articles
Drug evaluation: AP-23573--an mTOR inhibitor for the treatment of cancer. Journal Articles
E2F7 promotes mammalian target of rapamycin inhibitor resistance in hepatocellular carcinoma after liver transplantation Journal Articles
Effect of FKBP65, a putative elastin chaperone, on the coacervation of tropoelastin in vitro Journal Articles
Everolimus, when combined with exemestane, adds toxicity with minimal benefit for women with breast cancer Journal Articles
Everolimus-Eluting Stents or Bypass Surgery for Left Main Coronary Disease Journal Articles
Glucose transporter expression in L6 muscle cells: Regulation through insulin- and stress-activated pathways Journal Articles
Immunosuppression without calcineurin inhibition: optimization of renal function in expanded criteria donor renal transplantation Journal Articles
Intragraft CD11b+IDO+ Cells Mediate Cardiac Allograft Tolerance by ECDI-Fixed Donor Splenocyte Infusions Journal Articles
Long-term benefit using DES in STEMI patients. Journal Articles
Metastatic renal cell cancer treatments: An indirect comparison meta-analysis Journal Articles
Mortality in randomized controlled trials comparing drug-eluting vs. bare metal stents in coronary artery disease: a meta-analysis Journal Articles
Official American Thoracic Society/Japanese Respiratory Society Clinical Practice Guidelines: Lymphangioleiomyomatosis Diagnosis and Management Journal Articles
Opportunities for enhancing the care of older patients with ST-elevation myocardial infarction presenting for primary percutaneous coronary intervention: Rationale and design of the SAFE-STEMI for Seniors trial Journal Articles
PCI with drug-eluting stents ≤ 12 months before surgery was linked to increased MI and cardiac death after surgery Journal Articles
Paclitaxel Versus Sirolimus Stents in Diabetic and Nondiabetic Patients Journal Articles
Phase I study of vinblastine and temsirolimus in pediatric patients with recurrent or refractory solid tumors: Canadian Cancer Trials Group Study IND.218 Journal Articles
Phase II Study of Temsirolimus in Women With Recurrent or Metastatic Endometrial Cancer: A Trial of the NCIC Clinical Trials Group Journal Articles
Phase II study of oral ridaforolimus in women with recurrent or metastatic endometrial cancer Journal Articles
Phase II study of temsirolimus (CCI-779) in women with recurrent, unresectable, locally advanced or metastatic carcinoma of the cervix. A trial of the NCIC Clinical Trials Group (NCIC CTG IND 199) Journal Articles
Randomized Phase II Study Comparing Two Schedules of Everolimus in Patients With Recurrent/Metastatic Breast Cancer: NCIC Clinical Trials Group IND.163 Conferences
Rapamycin does not prevent increases in myofibrillar or mitochondrial protein synthesis following endurance exercise Journal Articles
Rapamycin has a beneficial effect on controlling epilepsy in children with tuberous sclerosis complex: results of 7 children from a cohort of 86 Journal Articles
Rapamycin inhibits transforming growth factor β‐induced peritoneal angiogenesis by blocking the secondary hypoxic response Journal Articles
Sirolimus and mTORC1: centre stage in the story of what makes muscles bigger? Journal Articles
Sirolimus for vascular anomalies associated with PTEN hamartoma tumor syndrome. Journal Articles
Surgical biology for the clinician: vascular effects of immunosuppression. Journal Articles
Targeted therapy for metastatic renal cell carcinoma Journal Articles
Temsirolimus in combination with carboplatin and paclitaxel in patients with advanced solid tumors: a NCIC-CTG, phase I, open-label dose-escalation study (IND 179) Journal Articles
The mTORC Pathway in the Antiphospholipid Syndrome Journal Articles
Very Late Stent Fracture Associated With a Sirolimus-eluting Stent Journal Articles