Pyrimidinones
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A PET study of brain 5-HT 2 receptors and their correlation with platelet 5-HT 2 receptors in healthy humans Journal Articles
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A dose-finding study with TAK-442, an oral factor Xa inhibitor, in patients undergoing elective total knee replacement surgery Journal Articles
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A placebo‐controlled exploratory study investigating the efficacy and safety of the phosphodiesterase type 5 inhibitor UK‐369,003 for the treatment of men with storage lower urinary tract symptoms associated with a clinical diagnosis of overactive bladder Journal Articles
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A placebo‐controlled study investigating the efficacy and safety of the phosphodiesterase type 5 inhibitor UK‐369,003 for the treatment of men with lower urinary tract symptoms associated with clinical benign prostatic hyperplasia Journal Articles
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Antiviral activity and safety of aplaviroc, a CCR5 antagonist, in combination with lopinavir/ritonavir in HIV‐infected, therapy‐naïve patients: results of the EPIC study (CCR100136)* Journal Articles
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Clinical Impact of Double Protease Inhibitor Boosting with Lopinavir/Ritonavir and Amprenavir as Part of Salvage Antiretroviral Therapy Journal Articles
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Cortical Serotonin Type-2 Receptor Density in Parents of Children with Autism Spectrum Disorders Journal Articles
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Disruption of β-catenin/CBP signaling inhibits human airway epithelial–mesenchymal transition and repair Journal Articles
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Dysfunctional Attitudes and 5-HT2Receptors During Depression and Self-Harm Journal Articles
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KEYNOTE-022: Pembrolizumab with trametinib in patients with BRAF wild-type melanoma or advanced solid tumours irrespective of BRAF mutation Journal Articles
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LOGGIC/FIREFLY-2: a phase 3, randomized trial of tovorafenib vs. chemotherapy in pediatric and young adult patients with newly diagnosed low-grade glioma harboring an activating RAF alteration Journal Articles
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Network meta-analysis of therapies for previously untreated advanced BRAF-mutated melanoma Journal Articles
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PTEN status is a crucial determinant of the functional outcome of combined MEK and mTOR inhibition in cancer Journal Articles
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Phase 2 study of TAK-442, an oral factor Xa inhibitor, in patients following acute coronary syndrome Journal Articles
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Phase I pharmacokinetic study of single agent trametinib in patients with advanced cancer and hepatic dysfunction Journal Articles
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Prefrontal Cortex 5-HT2 Receptors in Depression: An [18F]Setoperone PET Imaging Study Journal Articles
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Randomized Controlled Trial of Once-Daily Tenofovir, Lamivudine, and Lopinavir/Ritonavir Versus Remaining on the Same Regimen in Virologically Suppressed HIV-Infected Patients on Their First PI-Containing HAART Regimen Journal Articles
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Sam68 Allows Selective Targeting of Human Cancer Stem Cells Journal Articles
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Serotonin 5-HT2Receptors in Schizophrenia: A PET Study Using [18F]Setoperone in Neuroleptic-Naive Patients and Normal Subjects Journal Articles
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Small Molecule Antagonists of the Wnt/Beta-Catenin Signaling Pathway Target Breast Tumor-Initiating Cells in a Her2/Neu Mouse Model of Breast Cancer Journal Articles
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Systemic therapy for previously untreated advanced BRAF-mutated melanoma: navigating a shifting landscape Journal Articles
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The Effect of Paroxetine on 5-HT2AReceptors in Depression: An [18F]Setoperone PET Imaging Study Journal Articles