Pyrimidinones Concept

subject area of

• A PET study of brain 5-HT 2 receptors and their correlation with platelet 5-HT 2 receptors in healthy humans  Academic Article
• A dose-finding study with TAK-442, an oral factor Xa inhibitor, in patients undergoing elective total knee replacement surgery  Academic Article
• A placebo-controlled exploratory study investigating the efficacy and safety of the phosphodiesterase type 5 inhibitor UK-369,003 for the treatment of men with storage lower urinary tract symptoms associated with a clinical diagnosis of overactive bladder  Academic Article
• A placebo-controlled study investigating the efficacy and safety of the phosphodiesterase type 5 inhibitor UK-369,003 for the treatment of men with lower urinary tract symptoms associated with clinical benign prostatic hyperplasia  Academic Article
• Antiviral activity and safety of aplaviroc, a CCR5 antagonist, in combination with lopinavir/ritonavir in HIV-infected, therapy-naïve patients: results of the EPIC study (CCR100136)  Academic Article
• Clinical Impact of Double Protease Inhibitor Boosting with Lopinavir/Ritonavir and Amprenavir as Part of Salvage Antiretroviral Therapy  Academic Article
• Cortical Serotonin Type-2 Receptor Density in Parents of Children with Autism Spectrum Disorders  Academic Article
• Disruption of β-catenin/CBP signaling inhibits human airway epithelial–mesenchymal transition and repair  Academic Article
• Dysfunctional Attitudes and 5-HT₂Receptors During Depression and Self-Harm  Academic Article
• KEYNOTE-022: Pembrolizumab with trametinib in patients with BRAF wild-type melanoma or advanced solid tumours irrespective of BRAF mutation  Academic Article
• Network meta-analysis of therapies for previously untreated advanced BRAF-mutated melanoma  Academic Article
• PTEN status is a crucial determinant of the functional outcome of combined MEK and mTOR inhibition in cancer  Academic Article
• Phase 2 study of TAK-442, an oral factor Xa inhibitor, in patients following acute coronary syndrome  Academic Article
• Phase I pharmacokinetic study of single agent trametinib in patients with advanced cancer and hepatic dysfunction  Academic Article
• Prefrontal Cortex 5-HT₂ Receptors in Depression: An [¹⁸F]Setoperone PET Imaging Study  Academic Article
• Randomized Controlled Trial of Once-Daily Tenofovir, Lamivudine, and Lopinavir/Ritonavir Versus Remaining on the Same Regimen in Virologically Suppressed HIV-Infected Patients on Their First PI-Containing HAART Regimen  Academic Article
• Sam68 Allows Selective Targeting of Human Cancer Stem Cells  Academic Article
• Serotonin 5-HT₂Receptors in Schizophrenia: A PET Study Using [¹⁸F]Setoperone in Neuroleptic-Naive Patients and Normal Subjects  Academic Article
• Small Molecule Antagonists of the Wnt/Beta-Catenin Signaling Pathway Target Breast Tumor-Initiating Cells in a Her2/Neu Mouse Model of Breast Cancer  Academic Article
• Systemic therapy for previously untreated advanced BRAF-mutated melanoma: navigating a shifting landscape  Academic Article
• The Effect of Paroxetine on 5-HT_2AReceptors in Depression: An [¹⁸F]Setoperone PET Imaging Study  Academic Article