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Dysfunctional Attitudes and 5-HT2 Receptors During...
Journal article

Dysfunctional Attitudes and 5-HT2 Receptors During Depression and Self-Harm

Abstract

OBJECTIVE: Dysfunctional attitudes are negatively biased assumptions and beliefs regarding oneself, the world, and the future. In healthy subjects, increasing serotonin (5-HT) agonism with a single dose of d-fenfluramine lowered dysfunctional attitudes. To investigate whether the converse, a low level of 5-HT agonism, could account for the higher levels of dysfunctional attitudes observed in patients with major depression or with self-injurious …

Authors

Meyer JH; McMain S; Kennedy SH; Korman L; Brown GM; DaSilva JN; Wilson AA; Blak T; Eynan-Harvey R; Goulding VS

Journal

American Journal of Psychiatry, Vol. 160, No. 1, pp. 90–99

Publisher

American Psychiatric Association Publishing

Publication Date

January 1, 2003

DOI

10.1176/appi.ajp.160.1.90

ISSN

0002-953X