subject area of
- A phase I dose-escalation study of apatorsen (OGX-427), an antisense inhibitor targeting heat shock protein 27 (Hsp27), in patients with castration-resistant prostate cancer and other advanced cancers Conferences
- A randomized phase 2 study of a HSP27 targeting antisense, apatorsen with prednisone versus prednisone alone, in patients with metastatic castration resistant prostate cancer Journal Articles
- Alterations in Mitochondrial and Apoptosis‐regulating Gene Expression in Photodynamic Therapy‐resistant Variants of HT29 Colon Carcinoma Cells¶ Journal Articles
- Apatorsen plus docetaxel versus docetaxel alone in platinum-resistant metastatic urothelial carcinoma (Borealis-2) Journal Articles
- Cooperative Interactions between Androgen Receptor (AR) and Heat-Shock Protein 27 Facilitate AR Transcriptional Activity Journal Articles
- Heat shock protein-27 attenuates foam cell formation and atherogenesis by down-regulating scavenger receptor-A expression via NF-κB signaling Journal Articles
- Increased BNip3 and decreased mutant p53 in cisplatin-sensitive PDT-resistant HT29 cells Journal Articles
- Inhibition of HSP27 blocks fibrosis development and EMT features by promoting Snail degradation Journal Articles
- Photodynamic Therapy Resistant Human Colon Carcinoma HT29 Cells Show Cross‐Resistance to UVA but not UVC Light Journal Articles
- Up-regulation of Hsp27 Plays a Role in the Resistance of Human Colon Carcinoma HT29 Cells to Photooxidative Stress¶ Journal Articles