subject area of
- A 2.13 Å Structure of E. coli Dihydrofolate Reductase Bound to a Novel Competitive Inhibitor Reveals a New Binding Surface Involving the M20 Loop Region Journal Articles
- A non-reactive natural product precursor of the duocarmycin family has potent and selective antimalarial activity Journal Articles
- An Expedient and Facile One-Step Synthesis of a Biguanide Library by Microwave Irradiation Coupled with Simple Product Filtration. Inhibitors of Dihydrofolate Reductase Journal Articles
- Experimental Screening of Dihydrofolate Reductase Yields a “Test Set” of 50,000 Small Molecules for a Computational Data-Mining and Docking Competition Journal Articles
- High throughput screening identifies novel inhibitors of Escherichia coli dihydrofolate reductase that are competitive with dihydrofolate Journal Articles
- Hydrothermal growth of free standing TiO2 nanowire membranes for photocatalytic degradation of pharmaceuticals Journal Articles
- Pemetrexed safety and dosing strategy Journal Articles
- Phase II Study of Pemetrexed With and Without Folic Acid and Vitamin B12 as Front-Line Therapy in Malignant Pleural Mesothelioma Journal Articles
- Phase II study of pemetrexed disodium, a multitargeted antifolate, and cisplatin as first-line therapy in patients with advanced nonsmall cell lung carcinoma Journal Articles
- Purification and properties of dihydrofolate reductase from cultured mammalian cells Journal Articles
- Purification of tetrahydrofolate dehydrogenase by affinity chromatography Journal Articles
- Pyrimethamine as a Potent and Selective Inhibitor of Acute Myeloid Leukemia Identified by High-throughput Drug Screening Journal Articles
- STABILIZATION OF DIHYDROFOLATE REDUCTASE BY INHIBITORS IN VIVO AND IN VITRO* Journal Articles
- Thermodynamic and NMR analysis of inhibitor binding to dihydrofolate reductase Journal Articles