selected scholarly activity
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conferences
- Studies of cell-free DNA and protein C in pediatric patients with septic shock enrolled into the SQUEEZE Trial. Canadian Journal of Anaesthesia. 2024
- Exploring the Experiences of Substitute Decision Makers with Exception to Consent in a Pediatric Resuscitation Trial. Circulation. 2024
- SQUEEZE Trial: A trial to determine whether septic shock is quicker in pediatric patients randomized to an early goal directed fluid-sparing strategy vs. usual care (SQUEEZE).. Pediatric Critical Care Medicine. 2024
- Timelines and Challenges Getting Multi-Centre Research Up and Running: Experience From the SQUEEZE Trial. Pediatric Critical Care Medicine. 2024
- SQUEEZE Trial: A Trial to Determine whether Septic Shock Reversal is Quicker in Pediatric Patients Randomized to an Early Goal Directed Fluid Sparing Strategy vs. Usual Care 2023
- Exception to Consent in Pediatric Resuscitation Research: Exploring the Experiences of Substitute Decision Makers. Circulation. 2016
- BARRIERS AND FACILITATORS OF HIGH-QUALITY RCTS IN PEDIATRIC CRITICAL CARE: A SURVEY OF TRIALISTS. Critical Care Medicine. 2015
- Determining the Timeliness of Key Resuscitative Interventions Among Pediatric Patients Treated for Septic Shock at a Pediatric Tertiary Care Hospital. Circulation. 2014
- A Randomized Trial Of Different Strategies For Introducing Research To Substitute Decision Makers: The Approach Trial (quantitative Study). American Journal of Respiratory and Critical Care Medicine. 2014
- Experimental use of a Pediatric Fluid Resuscitation Model: Evaluating Test-retest Reliability and Inter-subject Variability. Circulation. 2013
- Rapid Pediatric Fluid Resuscitation: A Randomized Controlled Trail Comparing the Efficiency of Two Provider Endorsed Manual Fluid Resuscitation Techniques. Circulation. 2013
- Sodium Bicarbonate Use in Pediatric Shock and Cardiac Arrest: Attitudes of Pediatric Acute Care Physicians. Circulation. 2010
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journal articles
- PP207 Topic: AS19–Other: Ethics/Endocrine/Metabolism/Burns/Genetics/Rheumatology/Other: TIMELINES AND CHALLENGES GETTING MULTI-CENTRE RESEARCH UP AND RUNNING: EXPERIENCE FROM THE SQUEEZE TRIAL. Pediatric Critical Care Medicine. 25:e72-e73. 2024
- PP407 Topic: AS14–Infections: Sepsis and Septic Shock/Antimicrobial Stewardship/Tropical and Parasite Infections/Other: A TRIAL TO DETERMINE WHETHER SEPTIC SHOCK REVERSAL IS QUICKER IN PEDIATRIC PATIENTS RANDOMIZED TO AN EARLY GOAL-DIRECTED FLUID-SPARING STRATEGY VS. USUAL CARE (SQUEEZE). Pediatric Critical Care Medicine. 25:e125-e125. 2024
- Lightweight transformers for clinical natural language processing. Natural Language Engineering. 30:1-28. 2024
- At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods. Scientific Reports. 14:16387. 2024
- Barriers, Solutions, and Opportunities for Adapting Critical Care Clinical Trials in the COVID-19 Pandemic. JAMA network open. 7:e2420458-e2420458. 2024
- Statistical analysis plan for the SQUEEZE trial: A trial to determine whether septic shock reversal is quicker in pediatric patients randomized to an early goal-directed fluid-sparing strategy vs. usual care (SQUEEZE). Critical Care and Resuscitation. 26:123-134. 2024
- Characteristics and outcomes of COVID-19 patients admitted to hospital with and without respiratory symptoms. Trials in Vaccinology. 10:e29591-e29591. 2024
- Emergency research without prior consent in the United States, Canada, European Union and United Kingdom: How regulatory differences affect study design and implementation in cardiac arrest trials. Resuscitation Plus. 17:100565-100565. 2024
- Implementation of Recommendations on the use of Corticosteroids in Severe COVID-19. JAMA network open. 6:e2346502-e2346502. 2023
- Characteristics and outcomes of an international cohort of 600 000 hospitalized patients with COVID-19. International Journal of Epidemiology. 52:355-376. 2023
- Neurological manifestations of COVID-19 in adults and children. Brain. 146:1648-1661. 2023
- Association of body mass index with COVID-19 related in-hospital death. Clinical Nutrition. 41:2924-2926. 2022
- Paediatric COVID-19 mortality: a database analysis of the impact of health resource disparity. BMJ Paediatrics Open. 6:e001657-e001657. 2022
- Respiratory support in patients with severe COVID-19 in the International Severe Acute Respiratory and Emerging Infection (ISARIC) COVID-19 study: a prospective, multinational, observational study. Critical Care. 26:276. 2022
- Implementation and facilitation of post-resuscitation debriefing: a comparative crossover study of two post-resuscitation debriefing frameworks. BMC Emergency Medicine. 22:152. 2022
- ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19. Scientific data. 9:454. 2022
- Balanced Versus Unbalanced Fluid in Critically Ill Children: Systematic Review and Meta-Analysis*. Pediatric Critical Care Medicine. 23:181-191. 2022
- Clinical characteristics, risk factors and outcomes in patients with severe COVID-19 registered in the International Severe Acute Respiratory and Emerging Infection Consortium WHO clinical characterisation protocol: a prospective, multinational, multicentre, observational study. ERJ Open Research. 8:00552-2021. 2022
- Adherence of Clinical Practice Guidelines for Pharmacologic Treatments of Hospitalized Patients With COVID-19 to Trustworthy Standards. JAMA network open. 4:e2136263-e2136263. 2021
- PRagMatic Pediatric Trial of Balanced vs nOrmaL Saline FlUid in Sepsis: study protocol for the PRoMPT BOLUS randomized interventional trial. Trials. 22:776. 2021
- The value of open-source clinical science in pandemic response: lessons from ISARIC. The Lancet Infectious Diseases. 21:1623-1624. 2021
- Ten months of temporal variation in the clinical journey of hospitalised patients with COVID-19: An observational cohort. eLife. 10:e70970. 2021
- P0181 / #1250: BALANCED VERSUS UNBALANCED FLUID IN CRITICALLY-ILL CHILDREN: SYSTEMATIC REVIEW AND META-ANALYSIS. Pediatric Critical Care Medicine. 22:116-116. 2021
- Applications of Postresuscitation Debriefing Frameworks in Emergency Settings: A Systematic Review. AEM Education and Training. 4:223-230. 2020
- Fast I(n)dentification of Pathogens in Neonates (FINDPATH-N): protocol for a prospective pilot cohort study of next-generation sequencing for pathogen identification in neonates with suspected sepsis. BMJ Paediatrics Open. 4:e000651-e000651. 2020
- Impact of balanced versus unbalanced fluid resuscitation on clinical outcomes in critically ill children: protocol for a systematic review and meta-analysis. Systematic Reviews. 8:195. 2019
- What Goes Up, Must Go Down?*. Pediatric Critical Care Medicine. 19:579-581. 2018
- Defining Significant Events for Neonatal and Pediatric Transport: Results of a Combined Delphi and Consensus Meeting Process. Journal of Pediatric Intensive Care. 06:165-175. 2017
- Neuroimaging in Sepsis: Panacea or Pandora’s Box?*. Pediatric Critical Care Medicine. 18:716-717. 2017
- High-Quality Randomized Controlled Trials in Pediatric Critical Care: A Survey of Barriers and Facilitators*. Pediatric Critical Care Medicine. 18:405-413. 2017
- A trial to determine whether septic shock-reversal is quicker in pediatric patients randomized to an early goal-directed fluid-sparing strategy versus usual care (SQUEEZE): study protocol for a pilot randomized controlled trial. Trials. 17:556. 2016
- Exploring the experiences of substitute decision-makers with an exception to consent in a paediatric resuscitation randomised controlled trial: study protocol for a qualitative research study. BMJ Open. 6:e012931-e012931. 2016
- 325. Critical Care Medicine. 43:83-83. 2015
- Part 2: Evidence Evaluation and Management of Conflicts of Interest. Circulation. 132:S368-S382. 2015
- Cost Consequence Analysis of Implementing the Low Risk Ankle Rule in Emergency Departments. Annals of Emergency Medicine. 66:455-463.e4. 2015
- Part 6: Pediatric Basic Life Support and Pediatric Advanced Life Support. Circulation. 132:S177-S203. 2015
- Part 6: Pediatric basic life support and pediatric advanced life support. Resuscitation. 95:e147-e168. 2015
- Fluid resuscitation for toddlers and young children. Paediatric Anaesthesia. 25:538-540. 2015
- Is there a role for physician involvement in introducing research to surrogate decision makers in the intensive care unit? (The Approach trial: a pilot mixed methods study). Intensive Care Medicine. 41:58-67. 2015
- Evaluating the test re-test reliability and inter-subject variability of health care provider manual fluid resuscitation performance. BMC Research Notes. 7:724. 2014
- Identifying Significant and Relevant Events During Pediatric Transport. Pediatric Critical Care Medicine. 15:653-659. 2014
- Rapid paediatric fluid resuscitation: a randomised controlled trial comparing the efficiency of two provider-endorsed manual paediatric fluid resuscitation techniques in a simulated setting. BMJ Open. 4:e005028-e005028. 2014
- ABSTRACT 683. Pediatric Critical Care Medicine. 15:154-154. 2014
- ABSTRACT 684. Pediatric Critical Care Medicine. 15:154-154. 2014
- Factors affecting pediatric isotonic fluid resuscitation efficiency: a randomized controlled trial evaluating the impact of syringe size. BMC Emergency Medicine. 13:14. 2013
- Abstract 197: Rapid Pediatric Fluid Resuscitation: A Randomized Controlled Trial Comparing the Efficiency of Two Provider Endorsed Manual Fluid Resuscitation Techniques. Circulation. 128. 2013
- Effect of the Low Risk Ankle Rule on the frequency of radiography in children with ankle injuries. CANADIAN MEDICAL ASSOCIATION JOURNAL. 185:E731-E738. 2013
- Sodium Bicarbonate Use in Shock and Cardiac Arrest. Critical Care Medicine. 41:2188-2195. 2013
- Study protocol for a randomised controlled trial comparing the efficiency of two provider-endorsed manual paediatric fluid resuscitation techniques. BMJ Open. 3:e002754-e002754. 2013
- Translating Resuscitation Guidelines into Practice: Health Care Provider Attitudes, Preferences and Beliefs Regarding Pediatric Fluid Resuscitation Performance. PLoS ONE. 8:e58282-e58282. 2013
- Prospective evaluation of direct approach with a tablet device as a strategy to enhance survey study participant response rate. BMC Research Notes. 5:605. 2012
- Rapid, easy, and cheap randomization: prospective evaluation in a study cohort. Trials. 13:90. 2012
- Ethical Considerations Related to Mobile Technology Use in Medical Research. Journal of Mobile Technology in Medicine. 1:50-52. 2012
- Predictors of major intervention in infants with bronchiolitis. Pediatric Pulmonology. 44:358-363. 2009
- PREDICTORS OF MAJOR INTERVENTION IN INFANTS WITH BRONCHIOLITIS. Pediatric Emergency Care. 23:768-768. 2007
- Paediatric emergency department staff perceptions of infection control measures against severe acute respiratory syndrome. Emergency Medicine Journal. 23:349-353. 2006
- 28 Paediatric Emergency Department Staff Perceptions of Infection Control Measures against Severe Acute Respiratory Syndrome. Paediatrics and Child Health. 9:27A-28A. 2004
- Portal vein thrombosis causing neonatal cerebral infarction. Archives of Disease in Childhood: Fetal and Neonatal Edition. 87:125F-127. 2002
- http://www.journalmtm.com/2012/use-of-a-tablet-to-enhance-standardisation-procedures-in-a-randomised-trial/. Journal of Mobile Technology in Medicine. 1:24-26.
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other
- SQUEEZE fluid-sparing (intervention) and usual care (control) management strategies 2024
- Ascertainment of shock reversal in various participant clinical scenarios in SQUEEZE 2024
- SQUEEZE Trial Protocol V6 - Final Version 2023
- SQUEEZE Trial Data Dictionary - Final Version 2019
- Participant entry into the SQUEEZE trial and flow through the protocol 2016
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preprints
- The SQUEEZE pilot trial: a trial to determine whether septic shock reversal is quicker in pediatric patients randomized to an early goal directed fluid-sparing strategy vs. usual care 2024
- An international observational study to assess the impact of the Omicron variant emergence on the clinical epidemiology of COVID-19 in hospitalised patients 2022