Journal article
Type 2 diabetes influences bacterial tissue compartmentalisation in human obesity
Abstract
Visceral obesity is a key risk factor for type 2 diabetes (T2D). Whereas gut dysbiosis appears to be instrumental for this relationship, whether gut-associated signatures translocate to extra-intestinal tissues and how this affects host metabolism remain elusive. Here we provide a comparative analysis of the microbial profile found in plasma, liver and in three distinct adipose tissues of individuals with morbid obesity. We explored how these …
Authors
Anhê FF; Jensen BAH; Varin TV; Servant F; Van Blerk S; Richard D; Marceau S; Surette M; Biertho L; Lelouvier B
Journal
Nature Metabolism, Vol. 2, No. 3, pp. 233–242
Publisher
Springer Nature
Publication Date
March 2020
DOI
10.1038/s42255-020-0178-9
ISSN
2522-5812