selected scholarly activity
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academic article
- Alterations in fecal β-defensin-3 secretion as a marker of instability of the gut microbiota. Gut Microbes. 15:2233679. 2023
- Gut microbiota modulates visceral sensitivity through calcitonin gene-related peptide (CGRP) production. Gut Microbes. 15:2188874. 2023
- Associations of intrapartum antibiotics and growth, atopy, gastrointestinal and sleep outcomes at one year of age. Pediatric Research. 94:1026-1034. 2023
- Gut Microbiome Composition Is Associated With Future Onset of Crohn’s Disease in Healthy First-Degree Relatives. Gastroenterology. 165:670-681. 2023
- Postmortem examination of equids >1-year-old with enterotyphlocolitis in Ontario: a retrospective descriptive study. Journal of Veterinary Diagnostic Investigation. 35:350-354. 2023
- SARS-CoV-2 Outbreak Investigation Using Contact Tracing and Whole-Genome Sequencing in an Ontario Tertiary Care Hospital. Microbiology spectrum. 11:e0190022. 2023
- Definitions, rates and associated mortality of ICU-acquired pneumonia: A multicenter cohort study. Journal of Critical Care. 75:154284-154284. 2023
- Author Correction: Chronic exposure to synthetic food colorant Allura Red AC promotes susceptibility to experimental colitis via intestinal serotonin in mice. Nature Communications. 14:3125. 2023
- Deep learning-guided discovery of an antibiotic targeting Acinetobacter baumannii. Nature Chemical Biology. 2023
- Anti-Integrin αvβ6 Autoantibodies Are a Novel Biomarker That Antedate Ulcerative Colitis. Gastroenterology. 164:619-629. 2023
- Effect of dietary iron supplementation on the equine fecal microbiome.. Canadian Journal of Veterinary Research. 87:97-104. 2023
- A267 IDENTIFYING ENTEROBACTERIACEAE VIRULENCE GENES ASSOCIATED WITH ACTIVE DISEASE IN ULCERATIVE COLITIS PATIENTS USING CULTURE-DEPENDENT AND -INDEPENDENT APPROACHES. Journal of the Canadian Association of Gastroenterology. 6:84-85. 2023
- A33 EFFECTS OF THE NEXT GENERATION PROBIOTIC, AKKERMANSIA MUCINIPHILA, ON INTESTINAL INFLAMMATION AND BARRIER FUNCTION. Journal of the Canadian Association of Gastroenterology. 6:18-18. 2023
- A8 MICROBIAL ACTIVATION OF INTESTINAL DENDRITIC CELLS IS CRITICAL FOR THE ESTABLISHMENT OF NORMAL BEHAVIOR. Journal of the Canadian Association of Gastroenterology. 6:4-5. 2023
- Human gut microbiota after bariatric surgery alters intestinal morphology and glucose absorption in mice independently of obesity. Gut. 72:460-471. 2023
- Phase II trial of cytoreductive stereotactic hypofractionated radiotherapy with combination ipilimumab/nivolumab for metastatic kidney cancer (CYTOSHRINK).. Journal of Clinical Oncology. 41:TPS750-TPS750. 2023
- Fecal prevalence of Clostridium innocuum DNA in healthy horses and horses with colitis. Anaerobe. 79:102681-102681. 2023
- Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies. Nature. 613:639-649. 2023
- Direct and culture-enriched 16S rRNA sequencing of cecal content of healthy horses and horses with typhlocolitis. PLoS One. 18:e0284193-e0284193. 2023
- Stenotrophomonas maltophilia natural history and evolution in the airways of adults with cystic fibrosis. Frontiers in Microbiology. 14:1205389. 2023
- Chronic exposure to synthetic food colorant Allura Red AC promotes susceptibility to experimental colitis via intestinal serotonin in mice. Nature Communications. 13:7617. 2022
- 511. The cefazolin (CZ) and piperacillin-tazobactam (TZP) inoculum effects (IEs) are persistent amongst serial isolates of methicillin-sensitive Staphylococcus aureus (MSSA) derived from the sputum of persons with cystic fibrosis (pwCF) despite variation in other phenotypes.. Open Forum Infectious Diseases. 9:ofac492.567-. 2022
- Human Gut Metagenomes Encode Diverse GH156 Sialidases. Applied and Environmental Microbiology. 88:e0175522. 2022
- Gut microbiota promotes stem cell differentiation through macrophage and mesenchymal niches in early postnatal development. Immunity. 55:2300-2317.e6. 2022
- Iron in airway macrophages and infective exacerbations of chronic obstructive pulmonary disease. Respiratory Research. 23:8. 2022
- Biogeographic Variation and Functional Pathways of the Gut Microbiota in Celiac Disease. Gastroenterology. 163:1351-1363.e15. 2022
- Dual Targeting Factors Are Required for LXG Toxin Export by the Bacterial Type VIIb Secretion System. mBio. 13:e0213722. 2022
- The natural history and genetic diversity of Haemophilus influenzae infecting the airways of adults with cystic fibrosis. Scientific Reports. 12:15765. 2022
- Exploring the Cystic Fibrosis Lung Microbiome: Making the Most of a Sticky Situation. Journal of the Pediatric Infectious Diseases Society. 11:S13-S22. 2022
- High-fructose feeding suppresses cold-stimulated brown adipose tissue glucose uptake independently of changes in thermogenesis and the gut microbiome. Cell Reports Medicine. 3:100742-100742. 2022
- Mediterranean-Like Dietary Pattern Associations With Gut Microbiome Composition and Subclinical Gastrointestinal Inflammation. Gastroenterology. 163:685-698. 2022
- Effects of municipal wastewater effluents on the digestive gland microbiome of wild freshwater mussels (Lasmigona costata). Ecotoxicology and Environmental Safety. 241:113774-113774. 2022
- Histamine production by the gut microbiota induces visceral hyperalgesia through histamine 4 receptor signaling in mice. Science Translational Medicine. 14:eabj1895. 2022
- Metformin-induced reductions in tumor growth involves modulation of the gut microbiome. Molecular Metabolism. 61:101498-101498. 2022
- Probe design for simultaneous, targeted capture of diverse metagenomic targets. Cell Reports: Methods. 2:100246-100246. 2022
- P122 Identification and characterisation of a Liverpool Epidemic Strain (LES) isolate of Pseudomonas aeruginosa, first collected in 1986 in Calgary, Canada. Journal of Cystic Fibrosis. 21:S98-S98. 2022
- ePS3.09 Methicillin-sensitive Staphylococcus aureus (MSSa) with inoculum-related reduced susceptibility to cefazolin (CZ) and piperacillintazobactam (TZP) in persons with cystic fibrosis (pwCF). Journal of Cystic Fibrosis. 21:S51-S52. 2022
- Colitis-associated microbiota drives changes in behaviour in male mice in the absence of inflammation. Brain, Behavior, and Immunity. 102:266-278. 2022
- A229 GUT MICROBIOTA PROFILES, DIET AND SHORT-CHAIN FATTY ACIDS AS PREDICTORS OF GENERALIZED ANXIETY DISORDER. Journal of the Canadian Association of Gastroenterology. 5:120-121. 2022
- A46 BIOGEOGRAPHIC VARIATION AND FUNCTIONAL PATHWAYS OF THE GUT MICROBIOTA IN CELIAC DISEASE. Journal of the Canadian Association of Gastroenterology. 5:53-54. 2022
- A6 MECHANISMS UNDERLYING GUT DYSFUNCTION FOLLOWING C. DIFFICILE INFECTION AND IMPLICATIONS FOR TREATMENT. Journal of the Canadian Association of Gastroenterology. 5:6-8. 2022
- Altered microbiomes of aquatic macroinvertebrates and riparian spiders downstream of municipal wastewater effluents. Science of the Total Environment. 809:151156-151156. 2022
- Author Correction: Gain-of-function variants in SYK cause immune dysregulation and systemic inflammation in humans and mice. Nature Genetics. 54:213-213. 2022
- Gut microbiota-based vaccination engages innate immunity to improve blood glucose control in obese mice. Molecular Metabolism. 55:101404-101404. 2022
- Intestinal Microbial Composition of Children in a Randomized Controlled Trial of Probiotics to Treat Acute Gastroenteritis. Frontiers in Cellular and Infection Microbiology. 12:883163. 2022
- Azithromycin and the microbiota of cystic fibrosis sputum. BMC Microbiology. 21:96. 2021
- Disruption of autophagy by increased 5-HT alters gut microbiota and enhances susceptibility to experimental colitis and Crohn’s disease. Science advances. 7:eabi6442. 2021
- Over-celling fetal microbial exposure. Cell. 184:5839-5841. 2021
- Probe design for simultaneous, targeted capture of diverse metagenomic targets. Cell Reports: Methods. 1:100069-100069. 2021
- Effect of Probiotics on Incident Ventilator-Associated Pneumonia in Critically Ill Patients. JAMA: Journal of the American Medical Association. 326:1024-1024. 2021
- Lower brown adipose tissue activity is associated with non-alcoholic fatty liver disease but not changes in the gut microbiota. Cell Reports Medicine. 2:100397-100397. 2021
- The gut content microbiome of wild-caught rainbow darter is altered during laboratory acclimation. Comparative Biochemistry and Physiology Part D: Genomics and Proteomics. 39:100835-100835. 2021
- Changes in the gut microbiome associated with infliximab in patients with bipolar disorder. Brain and Behavior. 11:e2259. 2021
- Results of the First Pilot Randomized Controlled Trial of Fecal Microbiota Transplant In Pediatric Ulcerative Colitis: Lessons, Limitations, and Future Prospects. Gastroenterology. 161:388-393.e3. 2021
- Infants’ First Solid Foods: Impact on Gut Microbiota Development in Two Intercontinental Cohorts. Nutrients. 13:2639-2639. 2021
- Fetal meconium does not have a detectable microbiota before birth. Nature Microbiology. 6:865-873. 2021
- 425 RESULTS OF THE FIRST PILOT RANDOMIZED CONTROLLED TRIAL OF FAECAL MICROBIOTA TRANSPLANT FOR PEDIATRIC ULCERATIVE COLITIS. Gastroenterology. 160:S-89. 2021
- Neutrophilic asthma: misconception or misnomer?. The Lancet Respiratory Medicine. 9:441-443. 2021
- Gain-of-function variants in SYK cause immune dysregulation and systemic inflammation in humans and mice. Nature Genetics. 53:500-510. 2021
- Novel Fecal Biomarkers That Precede Clinical Diagnosis of Ulcerative Colitis. Gastroenterology. 160:1532-1545. 2021
- A29 NOVEL FECAL BIOMARKERS THAT PRECEDE CLINICAL DIAGNOSIS OF ULCERATIVE COLITIS. Journal of the Canadian Association of Gastroenterology. 4:268-269. 2021
- A39 CULTURE-ENRICHED METAGENOMICS REVEALED MICROBIAL ENGRAFTMENT FOLLOWING FMT IN PATIENTS WITH ULCERATIVE COLITIS. Journal of the Canadian Association of Gastroenterology. 4:269-270. 2021
- A51 ENTERIC PARASITE INFECTION-INDUCED ALTERATION OF THE GUT MICROBIOTA REGULATES INTESTINAL GOBLET CELL BIOLOGY AND MUCIN PRODUCTION VIA TLR2 SIGNALING. Journal of the Canadian Association of Gastroenterology. 4:7-8. 2021
- Characterizing the gut microbiota in adults with bipolar disorder: a pilot study. Nutritional Neuroscience. 24:173-180. 2021
- Exposure to high fructose corn syrup during adolescence in the mouse alters hepatic metabolism and the microbiome in a sex‐specific manner. The Journal of Physiology. 599:1487-1511. 2021
- Potential Contributions of Anaerobes in Cystic Fibrosis Airways. Journal of Clinical Microbiology. 59:e01813-e01819. 2021
- Capturing the diversity of the human milk microbiota through culture-enriched molecular profiling: a feasibility study. FEMS Microbiology Letters. 368:fnab001. 2021
- Muc2 Mucin and Nonmucin Microbiota Confer Distinct Innate Host Defense in Disease Susceptibility and Colonic Injury. CMGH Cellular and Molecular Gastroenterology and Hepatology. 11:77-98. 2021
- Rainbow darter (Etheostoma caeruleum) from a river impacted by municipal wastewater effluents have altered gut content microbiomes. Science of the Total Environment. 751:141724-141724. 2021
- Serum Zonulin Measured by Commercial Kit Fails to Correlate With Physiologic Measures of Altered Gut Permeability in First Degree Relatives of Crohn's Disease Patients. Frontiers in Physiology. 12:645303. 2021
- Nasal Tissue Extraction Is Essential for Characterization of the Murine Upper Respiratory Tract Microbiota. Clinical and Vaccine Immunology. 5:e00562-e00520. 2020
- Associations of NOD2 polymorphisms with Erysipelotrichaceae in stool of in healthy first degree relatives of Crohn’s disease subjects. BMC Medical Genomics. 21:204. 2020
- Completion of draft bacterial genomes by long-read sequencing of synthetic genomic pools. BMC Genomics. 21:519. 2020
- Increased Intestinal Permeability Is Associated With Later Development of Crohn’s Disease. Gastroenterology. 159:2092-2100.e5. 2020
- Sputum microbiota in adults with CF associates with response to inhaled tobramycin. Thorax. 75:1058-1064. 2020
- High Fat-High Fructose Diet-Induced Changes in the Gut Microbiota Associated with Dyslipidemia in Syrian Hamsters. Nutrients. 12:3557-3557. 2020
- IMAGINE Network’s Mind And Gut Interactions Cohort (MAGIC) Study: a protocol for a prospective observational multicentre cohort study in inflammatory bowel disease and irritable bowel syndrome. BMJ Open. 10:e041733-e041733. 2020
- The gut microbiome and inflammation in obsessive‐compulsive disorder patients compared to age‐ and sex‐matched controls: a pilot study. Acta Psychiatrica Scandinavica. 142:337-347. 2020
- Luminal and Mucosal Microbiota of the Cecum and Large Colon of Healthy and Diarrheic Horses. Animals. 10:1403-1403. 2020
- Starving the Gut: A Deficit of Butyrate in the Intestinal Ecosystem of Children With Intestinal Failure. Journal of Parenteral and Enteral Nutrition. 44:1112-1123. 2020
- The Gut Microbiota and Unhealthy Aging: Disentangling Cause from Consequence. Cell Host and Microbe. 28:180-189. 2020
- 616 RESULTS OF THE FIRST PAEDIATRIC RANDOMIZED-CONTROLLED TRIAL OF FAECAL MICROBIOTA TRANSPLANT FOR ULCERATIVE COLITIS. Gastroenterology. 158:S-132. 2020
- Development of the Microbiota and Associations With Birth Mode, Diet, and Atopic Disorders in a Longitudinal Analysis of Stool Samples, Collected From Infancy Through Early Childhood. Gastroenterology. 158:1584-1596. 2020
- Mo1906 FEASIBILITY OF THE FIRST PAEDIATRIC RANDOMIZED CONTROLLED PILOT TRIAL OF FAECAL MICROBIOTA TRANSPLANT FOR ULCERATIVE COLITIS. Gastroenterology. 158:S-972. 2020
- Su1853 CHARACTERISTICS OF SKIN LESIONS ASSOCIATED WITH ANTI-TUMOR NECROSIS FACTOR THERAPY OR OTHER BIOLOGIC AGENTS IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE: A PROSPECTIVE COHORT STUDY. Gastroenterology. 158:s-675-s-676. 2020
- Fast I(n)dentification of Pathogens in Neonates (FINDPATH-N): protocol for a prospective pilot cohort study of next-generation sequencing for pathogen identification in neonates with suspected sepsis. BMJ Paediatrics Open. 4:e000651-e000651. 2020
- Gut Microbiome Patterns Associated With Treatment Response in Patients With Major Depressive Disorder: Changements du microbiote intestinal associés à la réponse au traitement chez des patients souffrant de trouble dépressif majeur. Canadian Journal of Psychiatry. 65:278-280. 2020
- Differences in Gut Microbiota in Patients With vs Without Inflammatory Bowel Diseases: A Systematic Review. Gastroenterology. 158:930-946.e1. 2020
- Type 2 diabetes influences bacterial tissue compartmentalisation in human obesity. Nature Metabolism. 2:233-242. 2020
- A219 PROTECTIVE EFFECTS OF AKKERMANSIA MUCINIPHILA ON INTESTINAL BARRIER FUNCTION AND INFLAMMATION. Journal of the Canadian Association of Gastroenterology. 3:93-94. 2020
- A261 MICROBIOTA PROFILES OF PATIENTS WITH MENTAL DISODERS DIFFER FROM THOSE OF HEALTHY CONTROLS. Journal of the Canadian Association of Gastroenterology. 3:138-139. 2020
- A45 INFLAMMATION AND INTESTINAL PERMEABILITY IN PEDIATRIC SHORT BOWEL SYNDROME. Journal of the Canadian Association of Gastroenterology. 3:53-54. 2020
- A50 TRANSFER OF DEPRESSIVE-LIKE PHENOTYPE TO GNOTOBIOTIC MICE DEPENDS ON MICROBIAL FEATURES SPECIFIC TO INDIVIDUAL PATIENTS. Journal of the Canadian Association of Gastroenterology. 3:59-60. 2020
- Culture-enriched metagenomic sequencing enables in-depth profiling of the cystic fibrosis lung microbiota. Nature Microbiology. 5:379-390. 2020
- P375 Feasibility of the first paediatric randomised controlled pilot trial of faecal microbiota transplant for ulcerative colitis. Journal of Crohn's and Colitis. 14:S353-S354. 2020
- P416 Results of the first paediatric randomised controlled trial of faecal microbiota transplant for ulcerative colitis. Journal of Crohn's and Colitis. 14:S379-S380. 2020
- Assessment of Inter-Laboratory Variation in the Characterization and Analysis of the Mucosal Microbiota in Crohn’s Disease and Ulcerative Colitis. Frontiers in Microbiology. 11:2028. 2020
- Clinical Outcomes Associated With Escherichia coli Infections in Adults With Cystic Fibrosis: A Cohort Study. Open Forum Infectious Diseases. 7:ofz476. 2020
- Cystic Fibrosis Patients Infected With Epidemic Pseudomonas aeruginosa Strains Have Unique Microbial Communities. Frontiers in Cellular and Infection Microbiology. 10:173. 2020
- Epidemiology of E. coli in Cystic Fibrosis Airways Demonstrates the Capacity for Persistent Infection but Not Patient-Patient Transmission. Frontiers in Microbiology. 11:475. 2020
- Vitamin B12 Deficiency Alters the Gut Microbiota in a Murine Model of Colitis. Frontiers in Nutrition. 7:83. 2020
- Capturing the Resistome: a Targeted Capture Method To Reveal Antibiotic Resistance Determinants in Metagenomes. Antimicrobial Agents and Chemotherapy. 64:e01324-e01319. 2019
- Obesity during pregnancy results in maternal intestinal inflammation, placental hypoxia, and alters fetal glucose metabolism at mid-gestation. Scientific Reports. 9:17621. 2019
- The effects of cycled inhaled aztreonam on the cystic fibrosis (CF) lung microbiome. Journal of Cystic Fibrosis. 18:829-837. 2019
- The gut microbiome in psychiatry: A primer for clinicians. Depression and Anxiety. 36:1004-1025. 2019
- Medroxyprogesterone acetate alters the vaginal microbiota and microenvironment in a Kenyan sex worker cohort and is also associated with increased susceptibility to HIV-1 in humanized mice. Disease Models and Mechanisms. 12:dmm039669. 2019
- Analysis of Genetic Association of Intestinal Permeability in Healthy First-degree Relatives of Patients with Crohn’s Disease. Inflammatory Bowel Diseases. 25:1796-1804. 2019
- Oral selective serotonin reuptake inhibitors activate vagus nerve dependent gut-brain signalling. Scientific Reports. 9:14290. 2019
- Loss of Microbial Topography Precedes Infection in Infants. American Journal of Respiratory and Critical Care Medicine. 200:660-662. 2019
- Incidence, impact and natural history ofKlebsiellaspecies infections in cystic fibrosis: A longitudinal single center study. Canadian Journal of Respiratory, Critical Care, and Sleep Medicine. 3:148-154. 2019
- Gut Microbiota and Irritable Bowel Syndrome. Gastroenterology. 157:1-1. 2019
- Gut Microbiota in Patients With Irritable Bowel Syndrome—A Systematic Review. Gastroenterology. 157:97-108. 2019
- Evaluating probiotics for the prevention of ventilator-associated pneumonia: a randomised placebo-controlled multicentre trial protocol and statistical analysis plan for PROSPECT. BMJ Open. 9:e025228-e025228. 2019
- High‐fat diet intake modulates maternal intestinal adaptations to pregnancy and results in placental hypoxia, as well as altered fetal gut barrier proteins and immune markers. The Journal of Physiology. 597:3029-3051. 2019
- TLR2 Plays a Pivotal Role in Mediating Mucosal Serotonin Production in the Gut. Journal of Immunology. 202:3041-3052. 2019
- A longitudinal characterization of the Non-Cystic Fibrosis Bronchiectasis airway microbiome. Scientific Reports. 9:6871. 2019
- 1153 – Critical Role of Toll-Like Receptor 2 in Mediating Serotonin Production in Gut. Gastroenterology. 156:S-247. 2019
- Microbe and host interaction in gastrointestinal homeostasis. Psychopharmacology. 236:1623-1640. 2019
- A32 THE ROLE OF GUT MICROBIOTA AND TRACE AMINES IN A MURINE MODEL OF GENERALIZED ANXIETY DISORDER. Journal of the Canadian Association of Gastroenterology. 2:64-65. 2019
- A4 INVESTIGATING MICROBIAL ENGRAFTMENT VIA A COMPREHENSIVE CULTURE-ENRICHED AND CULTURE-INDEPENDENT METAGENOMICS IN PATIENTS WITH ULCERATIVE COLITIS. Journal of the Canadian Association of Gastroenterology. 2:9-10. 2019
- Duodenal bacterial proteolytic activity determines sensitivity to dietary antigen through protease-activated receptor-2. Nature Communications. 10:1198. 2019
- Modulation of Gut Microbiota Composition by Serotonin Signaling Influences Intestinal Immune Response and Susceptibility to Colitis. CMGH Cellular and Molecular Gastroenterology and Hepatology. 7:709-728. 2019
- Impact of CFTR modulation with Ivacaftor on Gut Microbiota and Intestinal Inflammation. Scientific Reports. 8:17834. 2018
- Bacterial DNA patterns identified using paired-end Illumina sequencing of 16S rRNA genes from whole blood samples of septic patients in the emergency room and intensive care unit. BMC Microbiology. 18:79. 2018
- Microbial dysbiosis and mortality during mechanical ventilation: a prospective observational study. Respiratory Research. 19:245. 2018
- 1481. Clinical Outcomes of Escherichia coli Infections in Cystic Fibrosis (CF) Patients. Open Forum Infectious Diseases. 5:S458-S458. 2018
- Pneumococcal Colonization and the Nasopharyngeal Microbiota of Children in Botswana. The Pediatric Infectious Disease Journal. 37:1176-1183. 2018
- Sputum microbiota is predictive of long-term clinical outcomes in young adults with cystic fibrosis. Thorax. 73:1016-1025. 2018
- Molecular Basis for Immunity Protein Recognition of a Type VII Secretion System Exported Antibacterial Toxin. Journal of Molecular Biology. 430:4344-4358. 2018
- Commensal microbiota induces colonic barrier structure and functions that contribute to homeostasis. Scientific Reports. 8:14184. 2018
- The Mla Pathway Plays an Essential Role in the Intrinsic Resistance of Burkholderia cepacia Complex Species to Antimicrobials and Host Innate Components. Journal of Bacteriology. 200:e00156-e00118. 2018
- Inflammation-related differences in mucosa-associated microbiota and intestinal barrier function in colonic Crohn’s disease. American Journal of Physiology: Gastrointestinal and Liver Physiology. 315:G420-G431. 2018
- Probiotics to Prevent Respiratory Infections in Nursing Homes: A Pilot Randomized Controlled Trial. Journal of the American Geriatrics Society. 66:1346-1352. 2018
- EPS3.04 Impact of CFTR modulation with ivacaftor on gut microbiota and intestinal inflammation. Journal of Cystic Fibrosis. 17:S42-S42. 2018
- Su1168 - Microbial Proteases Increase Sensitivity to Dietary Antigen Through Par-2 Signaling. Gastroenterology. 154:s-491-s-492. 2018
- Age-Associated Microbial Dysbiosis Promotes Intestinal Permeability, Systemic Inflammation, and Macrophage Dysfunction. Cell Host and Microbe. 23:570-570. 2018
- Changes in gut microbiota during development of compulsive checking and locomotor sensitization induced by chronic treatment with the dopamine agonist quinpirole. Behavioural Pharmacology. 29:211-224. 2018
- A13 PROTEOLYTIC BACTERIA PROMOTE INNATE IMMUNE ACTIVATION AND GLUTEN-INDUCED PATHOLOGY IN MICE.. Journal of the Canadian Association of Gastroenterology. 1:23-24. 2018
- A19 BACTERIAL PROTEASES INCREASE SENSITIVITY TO DIETARY ANTIGEN THROUGH PAR-2 SIGNALING. Journal of the Canadian Association of Gastroenterology. 1:31-32. 2018
- A278 ESCHERICHIA ABUNDANCE AND LOW FECAL BUTYRATE IN CHILDREN WITH INTESTINAL FAILURE. Journal of the Canadian Association of Gastroenterology. 1:402-403. 2018
- A288 DISTINCT ROLES IN INNATE HOST DEFENSE AND SUSCEPTIBILITY TO COLONIC INJURY IN MUC2 MUCIN DEFICIENT AND SUFFICIENT MICROBIOTA. Journal of the Canadian Association of Gastroenterology. 1:499-500. 2018
- A301 GUT MICROBIOTA FROM A PATIENT WITH GENERALIZED ANXIETY DISORDER INDUCES ANXIETY-LIKE BEHAVIOUR AND ALTERED BRAIN CHEMISTRY IN GNOTOBIOTIC MICE. Journal of the Canadian Association of Gastroenterology. 1:523-524. 2018
- A8 PROLONGED FASTING ALTERS THE GUT MICROBIOME AND PROTECTS AGAINST SALMONELLA -INDUCED GUT INFLAMMATION. Journal of the Canadian Association of Gastroenterology. 1:14-15. 2018
- Transformation of the Anticancer Drug Doxorubicin in the Human Gut Microbiome. ACS Infectious Diseases. 4:68-76. 2018
- Culture and Molecular Profiling of the Respiratory Tract Microbiota. Methods in Molecular Biology. 1849:49-61. 2018
- The murine female intestinal microbiota does not shift throughout the estrous cycle. PLoS One. 13:e0200729-e0200729. 2018
- A comprehensive evaluation of the sl1p pipeline for 16S rRNA gene sequencing analysis. Microbiome. 5:100. 2017
- Ethnic and diet-related differences in the healthy infant microbiome. Genome Medicine: medicine in the post-genomic era. 9:32. 2017
- Non-digestible oligosaccharides directly regulate host kinome to modulate host inflammatory responses without alterations in the gut microbiota. Microbiome. 5:135. 2017
- Oral treatment with Lactobacillus rhamnosus attenuates behavioural deficits and immune changes in chronic social stress. BMC Medicine. 15:7. 2017
- The effects of inhaled aztreonam on the cystic fibrosis lung microbiome. Microbiome. 5:51. 2017
- Intrapartum antibiotics for GBS prophylaxis alter colonization patterns in the early infant gut microbiome of low risk infants. Scientific Reports. 7:16527. 2017
- Streptococcus pneumoniae Colonization Is Required To Alter the Nasal Microbiota in Cigarette Smoke-Exposed Mice. Infection and Immunity. 85:e00434-e00417. 2017
- Functional Enterospheres Derived In Vitro from Human Pluripotent Stem Cells. Stem Cell Reports. 9:897-912. 2017
- The Nasopharyngeal Microbiota of Children With Respiratory Infections in Botswana. The Pediatric Infectious Disease Journal. 36:e211-e218. 2017
- How do probiotics and prebiotics function at distant sites?. Beneficial Microbes. 8:521-533. 2017
- Probiotic Bifidobacterium longum NCC3001 Reduces Depression Scores and Alters Brain Activity: A Pilot Study in Patients With Irritable Bowel Syndrome. Gastroenterology. 153:448-459.e8. 2017
- The Evolving Cystic Fibrosis Microbiome: A Comparative Cohort Study Spanning 16 Years. Annals of the American Thoracic Society. 14:1288-1297. 2017
- A broadly distributed toxin family mediates contact-dependent antagonism between gram-positive bacteria. eLife. 6:e26938. 2017
- Kisameet Glacial Clay: an Unexpected Source of Bacterial Diversity. mBio. 8:e00590-e00517. 2017
- Prevalence and Outcomes of Achromobacter Species Infections in Adults with Cystic Fibrosis: a North American Cohort Study. Journal of Clinical Microbiology. 55:2074-2085. 2017
- Pseudomonas aeruginosa-Derived Rhamnolipids and Other Detergents Modulate Colony Morphotype and Motility in the Burkholderia cepacia Complex. Journal of Bacteriology. 199:e00171-e00117. 2017
- Effect of freezing sputum on Pseudomonas aeruginosa population heterogeneity. Journal of Cystic Fibrosis. 16:353-357. 2017
- Age-Associated Microbial Dysbiosis Promotes Intestinal Permeability, Systemic Inflammation, and Macrophage Dysfunction. Cell Host and Microbe. 21:455-466.e4. 2017
- Long-term clinical outcomes of ‘Prairie Epidemic Strain’Pseudomonas aeruginosainfection in adults with cystic fibrosis. Thorax. 72:333-339. 2017
- The Microbiome of the Respiratory Tract After Heart Transplantation. Journal of Heart and Lung Transplantation. 36:S50-S50. 2017
- Milk Fat Globule Membrane Supplementation in Formula Modulates the Neonatal Gut Microbiome and Normalizes Intestinal Development. Scientific Reports. 7:45274. 2017
- The gut microbiota and psychiatric illness. Journal of Psychiatry and Neuroscience. 42:75-77. 2017
- Transplantation of fecal microbiota from patients with irritable bowel syndrome alters gut function and behavior in recipient mice. Science Translational Medicine. 9:eaaf6397. 2017
- Association of high-risk sexual behaviour with diversity of the vaginal microbiota and abundance of Lactobacillus. PLoS One. 12:e0187612-e0187612. 2017
- Longitudinal sampling of the lung microbiota in individuals with cystic fibrosis. PLoS One. 12:e0172811-e0172811. 2017
- Pneumococcal Colonization and the Nasopharyngeal Microbiota of Children in Botswana. Open Forum Infectious Diseases. 4:S233-S233. 2017
- A comparison of intestinal microbiota in a population of low-risk infants exposed and not exposed to intrapartum antibiotics: The Baby & Microbiota of the Intestine cohort study protocol. BMC Pediatrics. 16:183. 2016
- Capturing the diversity of the human gut microbiota through culture-enriched molecular profiling. Genome Medicine: medicine in the post-genomic era. 8:72. 2016
- Epidemiology and Clinical Outcomes of Serratia marcescens Infections in Adults With Cystic Fibrosis. Open Forum Infectious Diseases. 3:1228. 2016
- Probiotics: Prevention of Severe Pneumonia and Endotracheal Colonization Trial—PROSPECT: a pilot trial. Trials. 17:377. 2016
- Reemergence of Lower-Airway Microbiota in Lung Transplant Patients with Cystic Fibrosis. Annals of the American Thoracic Society. 13:2132-2142. 2016
- Brain microbiota disruption within inflammatory demyelinating lesions in multiple sclerosis. Scientific Reports. 6:37344. 2016
- Composition and immunological significance of the upper respiratory tract microbiota. FEBS Letters. 590:3705-3720. 2016
- Harmonization of Food-Frequency Questionnaires and Dietary Pattern Analysis in 4 Ethnically Diverse Birth Cohorts. The Journal of Nutrition. 146:2343-2350. 2016
- Duodenal Bacteria From Patients With Celiac Disease and Healthy Subjects Distinctly Affect Gluten Breakdown and Immunogenicity. Gastroenterology. 151:670-683. 2016
- A Modular, Tn 7 -Based System for Making Bioluminescent or Fluorescent Salmonella and Escherichia coli Strains. Applied and Environmental Microbiology. 82:4931-4943. 2016
- Early life nasal microbiota in infants with cystic fibrosis. The Lancet Respiratory Medicine. 4:595-596. 2016
- Staphylococcus aureus Protein A Mediates Interspecies Interactions at the Cell Surface of Pseudomonas aeruginosa. mBio. 7:e00538-e00516. 2016
- Unique microbial-derived volatile organic compounds in portal venous circulation in murine non-alcoholic fatty liver disease. Biochimica et Biophysica Acta: international journal of biochemistry and biophysics. 1862:1337-1344. 2016
- High-intensity exercise training increases the diversity and metabolic capacity of the mouse distal gut microbiota during diet-induced obesity. American Journal of Physiology: Endocrinology and Metabolism. 310:E982-E993. 2016
- Epidemic Pseudomonas aeruginosa infection in patients with cystic fibrosis is not a risk factor for poor clinical Outcomes following lung transplantation. Journal of Cystic Fibrosis. 15:392-399. 2016
- The gut microbiome: Potential innovations for the understanding and treatment of psychopathology.. Canadian Psychology. 57:67-75. 2016
- Understanding the natural history and clinical implications of airways infections in CF — Moving beyond the classics. Journal of Cystic Fibrosis. 15:270-271. 2016
- Histone deacetylase activity and recurrent bacterial bronchitis in severe eosinophilic asthma. Acta Allergologica. 71:571-575. 2016
- Looks Who’s Talking Now. Cell Host and Microbe. 19:429-430. 2016
- Streptococcus pneumoniae Colonization Disrupts the Microbial Community within the Upper Respiratory Tract of Aging Mice. Infection and Immunity. 84:906-916. 2016
- Metabolic and transcriptomic profiling of Streptococcus intermedius during aerobic and anaerobic growth. Metabolomics. 12. 2016
- Development and Validation of a PCR Assay To Detect the Prairie Epidemic Strain of Pseudomonas aeruginosa from Patients with Cystic Fibrosis. Journal of Clinical Microbiology. 54:489-491. 2016
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- Cyanide Toxicity to Burkholderia cenocepacia Is Modulated by Polymicrobial Communities and Environmental Factors. Frontiers in Microbiology. 7:725. 2016
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Program and Abstracts from the Canadian Digestive Diseases Week
- Structural & functional consequences of chronic psychosocial stress on the microbiome & host. Psychoneuroendocrinology. 63:217-227. 2016
- The Microbiome. Veterinary Pathology. 53:10-21. 2016
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- Erratum: Culture and molecular-based profiles show shifts in bacterial communities of the upper respiratory tract that occur with age. The ISME Journal: multidisciplinary journal of microbial ecology. 9:1268-1268. 2015
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Defective
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- EFFECT OF FREEZING SPUTUM ON PSEUDOMONAS AERUGINOSA (PA) POPULATION HETEROGENEITY. Pediatric Pulmonology. 306-307. 2016
- EPIDEMIC PSEUDOMONAS AERUGINOSA: A DRIVING FORCE IN THE CYSTIC FIBROSIS (CF) MICROBIOME?. Pediatric Pulmonology. 330-330. 2016
- Sex Work Alters the Vaginal Microbiome: A Comparison Between Sex Workers and Lower Risk Women from the Same Community in Nairobi, Kenya. AIDS Research and Human Retroviruses. 126-126. 2016
- THE EVOLVING CYSTIC FIBROSIS (CF) MICROBIOME: A LONGITUDINAL COHORT STUDY. Pediatric Pulmonology. 329-330. 2016
- T-cells induced by oral gluten challenge in patients with coeliac disease confirm the in vivo effects of gluten hydrolysed by intestinal bacteria from gnotobiotic mice. European Journal of Immunology. 453-453. 2016
- Multiple Sclerosis Lesions Show Perturbations in Cerebral Microbiota. Neurology. 2016
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- Multiple Sclerosis Lesions Show Perturbations in Cerebral Microbiota. Neurology. 2016
- Multiple Sclerosis Lesions Show Perturbations in Cerebral Microbiota. Neurology. 2016
- Multiple Sclerosis Lesions Show Perturbations in Cerebral Microbiota. Neurology. 2016
- Multiple Sclerosis Lesions Show Perturbations in Cerebral Microbiota. Neurology. 2016
- 545 Microbiota From an Active Celiac Donor Modulates Intraepithelial Lymphocyte Numbers and Phenotype in the Mouse Small Intestine. Gastroenterology. S114-S114. 2016
- Sa1398 Immunogenic Gluten Is Modulated by Small Intestinal Bacterial Hydrolysis. Gastroenterology. S304-S304. 2016
- Su1891 Colonization of Germ-Free Mice With Human Derived Microbiota Induces Progressive Ultrastructural, Innate, and Functional Changes in the Intestinal Barrier. Gastroenterology. S581-S581. 2016
- Su1897 Inflammation-Related Differences in Mucosa-Associated Microbiota and Paracellular Permeability in Crohn's Colitis. Gastroenterology. S582-S582. 2016
- Su1905 Fecal Microbiome Profiles of Ulcerative Colitis Patients With and Without Anxiety and/or Depression. Gastroenterology. S584-S585. 2016
- Enhanced Culturing Techniques Identify Unexpected Pathogens In Patients With Suspected Ventilator-Associated Infections: The Fast Identification Of Pathogens (findpath) Pilot Study. American Journal of Respiratory and Critical Care Medicine. 2016
- Purpose of the Conference: 2015 Transatlantic Airway Conference. Annals of the American Thoracic Society. S111-S111. 2015
- CHANGES IN THE STRUCTURE OF THE CYSTIC FIBROSIS MICROBIOME THROUGH TIME: A COHORT STUDY. Pediatric Pulmonology. 339-340. 2015
- CULTURE-ENRICHED METAGENOMIC SEQUENCING OF THE CYSTIC FIBROSIS LUNG MICROBIOTA PROVIDES A MORE THOROUGH UNDERSTANDING OF MICROBIAL PROCESSES DURING PULMONARY EXACERBATION. Pediatric Pulmonology. 305-305. 2015
- DEVELOPMENT AND VALIDATION OF A PCR ASSAY TO DETECT THE PRAIRIE EPIDEMIC STRAIN (PES) OF PSEUDOMONAS AERUGINOSA. Pediatric Pulmonology. 337-337. 2015
- DO INHALED ANTIBIOTICS IMPROVE LUNG FUNCTION THROUGH AN EFFECT ON THE CYSTIC FIBROSIS (CF) MICROBIOME?. Pediatric Pulmonology. 330-331. 2015
- LONGITUDINAL SAMPLING OF PATIENTS WITH CYSTIC FIBROSIS INDICATES CHANGES IN THE MICROBIAL COMMUNITY IN THE DAYS PRIOR TO ONSET OF PULMONARY EXACERBATION. Pediatric Pulmonology. 305-305. 2015
- Distinct Roles of the Mucus Layer and Microbiota in Conferring Innate Host Defense and Susceptibility to Disease. The FASEB Journal. 2015
- Fetal and Neonatal Exposure To Nicotine Results in Increased Adiposity: Role of the Gut Microbiome.. Reproductive Sciences. 360A-360A. 2015
- Microbiome Effects on Hematopoietic Eosinophil/Basophil Progenitor Phenotype: Implications for the Pathogenesis of Allergic Inflammation. Journal of Allergy and Clinical Immunology. AB65-AB65. 2015
- The Gut Microbiome in Patients with Anxiety, Depression and Inflammatory Bowel Disease. Neuropsychopharmacology. S289-S289. 2014
- REDUCTION IN P. AERUGINOSA SPUTUM DENSITY DURING A PULMONARY EXACERBATION IN CYSTIC FIBROSIS DOES NOT PREDICT CLINICAL RESPONSE. Pediatric Pulmonology. 250-250. 2014
- A randomized, placebo controlled trial of fecal microbiota therapy in active ulcerative colitis.. Gastroenterology. S159-S159. 2014
- Investigating the microbiome pre and post fecal microbiota therapy from active ulcerative colitis patients in a randomized placebo controlled trial. Gastroenterology. S902-S902. 2014
- The Adoptive Transfer of Anxiety and Gut Dysfunction From IBS Patients to Axenic Mice Through Microbiota Transplantation. Gastroenterology. S845-S845. 2014
- P378 BENEFICIAL EFFECT OF THE PROBIOTIC VSL-3 ON LIVER INJURY-ASSOCIATED SICKNESS BEHAVIOR DEVELOPMENT BY ALTERING SYSTEMIC IMMUNITY AND INHIBITING ACTIVATED MONOCYTES FROM ENTERING THE BRAIN. Journal of Hepatology. S194-S194. 2014
- Specific Crohn's Disease (CD) Associated Risk Alleles Are Associated With the Composition of the Intestinal Microbiota in Healthy First Degree Relatives (FDR) of CD Subjects. Gastroenterology. S57-S57. 2013
- The Relationship Between Common IBD-Associated Risk Alleles and Intestinal Permeability in a Cohort of Healthy First Degree Relatives of Individuals With Crohn's Disease. Gastroenterology. S835-S835. 2013
- alpha-Proteobacteria predominate in the human brain microbiome independent of host immune status. Journal of Neuroimmunology. 137-137. 2012
- Microbial colonization of germ-free mice induces marked change in behaviour that is independent of bacterial diversity. Neurogastroenterology and Motility. 77-77. 2012
- Transfer of IBS phenotype to GERM-free mice through microbiota transplantation. Neurogastroenterology and Motility. 33-33. 2012
- EXPLORING THE STREPTOCOCCUS ANTIBIOTIC RESISTOME IN ADULT CYSTIC FIBROSIS PATIENTS. Pediatric Pulmonology. 323-323. 2011
- MECHANISMS OF ANTIMICROBIAL RESISTANCE IN CYSTIC FIBROSIS AIRWAY ISOLATES OF THE STREPTOCOCCUS MILLERI GROUP. Pediatric Pulmonology. 329-329. 2011
- THE CYSTIC FIBROSIS LUNG MICROBIOME EXPOSES NOVEL MEMBERS OF THE GENUS STREPTOCOCCUS. Pediatric Pulmonology. 325-325. 2010
- CHARACTERIZATION OF STREPTOCOCCUS MILLERI ISOLATES FROM ADULT CYSTIC FIBROSIS PATIENTS. Pediatric Pulmonology. 340-341. 2009
- REAL-TIME PCR ASSAYS FOR DETECTION OF THE STREPTOCOCCUS MILLERI GROUP FROM CF CLINICAL SPECIMENS USING TARGETS FOR CPN60 AND 16S RRNA GENES. Pediatric Pulmonology. 335-335. 2009
- THE CULTURED MICROBIOME OF CYSTIC FIBROSIS AIRWAYS. Pediatric Pulmonology. 313-313. 2009
- WHOLE GENOME SEQUENCING AND COMPARATIVE GENOMIC ANALYSIS OF THE STREPTOCOCCUS MILLERI GROUP. Pediatric Pulmonology. 335-335. 2009
- Escherichea coli Biofilm Formation and Susceptibility in Response to Increased Shear Stresses. ASME 2008 Summer Bioengineering Conference, Parts A and B. 979-980. 2008
- 5-aminosalicylic acid selectivity modulates bacterial gene expression at concentrations which are not inhibitory to growth. Gastroenterology. A712-A712. 2007
- Development of a solid media for the selective isolation of Streptococcus milleri from cystic fibrosis (CF) sputum. Pediatric Pulmonology. 323-324. 2007
- Polymicrobial interactions in CF: Synergies and antagonisms in host response. Pediatric Pulmonology. 150-151. 2007
- The Wavelet Transformation for Temporal Gene Expression Analysis. IEEE Computer Society Conference on Computer Vision and Pattern Recognition Workshops. 148-148. 2005
- Identification of replication sites via a nonparametric method in bacteria. METMBS'03: PROCEEDINGS OF THE INTERNATIONAL CONFERENCE ON MATHEMATICS AND ENGINEERING TECHNIQUES IN MEDICINE AND BIOLOGICAL SCIENCES. 17-21. 2003
- GeneVis: visualization tools for genetic regulatory network dynamics. IEEE Visualization, 2002. VIS 2002.. 243-250. 2002
- Critical Role of Toll-Like Receptor 2 in Mediating Serotonin Production in Gut.. Gastroenterology 2019. S-247-S-247.
- Protective effects of Akkermansia muciniphilia on intestinal barrier function and inflammation.. Journal of the Canadian Association of Gastroenterology 2020. 93-93.
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