Michael Surette - McMaster Experts

Affiliations

McMaster University,
Faculty of Health Sciences, McMaster University
Member, McMaster Institute for Research on Aging (MIRA), McMaster University
Member, Michael G. DeGroote Institute for Infectious Disease Research (IIDR), Faculty of Health Sciences
Joint Appointment, Biochemistry & Biomedical Sciences, Faculty of Health Sciences
Professor, Medicine, Faculty of Health Sciences
Member, Centre for Metabolism, Obesity, and Diabetes Research (MODR), Faculty of Health Sciences
Member, Farncombe Family Digestive Health Research Institute, Faculty of Health Sciences
Canada Research Chair in Interdisciplinary Microbiome Research, McMaster University,

Scholarly Activity in McMaster Experts

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chapters
- Two-Component Signal Transduction Systems: Structure-Function Relationships and Mechanisms of Catalysis. 25-51. 2014
- A New Look at Secondary Metabolites. 307-322. 2008
- LuxS in cellular metabolism and cell-to-cell signaling. 117-150. 2006
conferences
- Development and Validation of an Integrative Risk Score for Future Risk of Crohn's Disease in Healthy First-Degree Relatives: A Multicenter Prospective Cohort Study.. Gastroenterology. 150-153.e4. 2025
- 209 Prevalence of Antimicrobial Resistance Genes and Mobile Genetic Elements in the Swine Gut Microbiome. Journal of Animal Science. 131-132. 2023
- Effectiveness and cost of a comprehensive severe asthma management strategy guided by airway inflammometry. European Respiratory Journal. 2023
- Viral Presence Associated With Decreased Nasal Microbiome Alpha Diversity and Differential Relative Abundance in Infancy. American Journal of Respiratory and Critical Care Medicine. 2023
- Phase II trial of cytoreductive stereotactic hypofractionated radiotherapy with combination ipilimumab/nivolumab for metastatic kidney cancer (CYTOSHRINK).. Journal of Clinical Oncology. TPS398-TPS398. 2022
- Phase II trial of cytoreductive stereotactic hypofractionated radiotherapy with combination ipilimumab/nivolumab for metastatic kidney cancer (CYTOSHRINK). Journal of Clinical Oncology. 2022
- RESULTS OF THE FIRST PILOT RANDOMIZED CONTROLLED TRIAL OF FAECAL MICROBIOTA TRANSPLANT FOR PEDIATRIC ULCERATIVE COLITIS. Gastroenterology. S89-S89. 2021
- 335 The Gut-Lung Axis: The Human Perspective. Journal of Animal Science. 69-70. 2020
- Peripheral Artery Disease Patients With Chronic Limb-Threatening Ischemia Show Altered Blood Microbiota Composition Compared With Intermittent Claudication. Journal of Vascular Surgery. e348-e348. 2020
- EPIDEMIOLOGY AND NATURAL HISTORY OF HAEMOPHILUS INFLUENZAE INFECTIONS IN ADULTS WITH CYSTIC FIBROSIS. Pediatric Pulmonology. S172-S172. 2020
- THE SPUTUM MICROBIOME AND ITS ASSOCIATION WITH INCIDENT MYCOBACTEROIDES (MYCOBACTERIUM) ABSCESSUS INFECTION IN ADULTS WITH CF. Pediatric Pulmonology. S142-S143. 2020
- Peripheral Artery Disease Patients With Chronic Limb-Threatening Ischemia Show Altered Blood Microbiota Composition as Compared with Intermittent Claudication. Journal of Vascular Surgery. e212-e212. 2020
- CHARACTERISTICS OF SKIN LESIONS ASSOCIATED WITH ANTI-TUMOR NECROSIS FACTOR THERAPY OR OTHER BIOLOGIC AGENTS IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE: A PROSPECTIVE COHORT STUDY. Gastroenterology. S675-S676. 2020
- FEASIBILITY OF THE FIRST PAEDIATRIC RANDOMIZED CONTROLLED PILOT TRIAL OF FAECAL MICROBIOTA TRANSPLANT FOR ULCERATIVE COLITIS. Gastroenterology. S972-S972. 2020
- RESULTS OF THE FIRST PAEDIATRIC RANDOMIZED-CONTROLLED TRIAL OF FAECAL MICROBIOTA TRANSPLANT FOR ULCERATIVE COLITIS. Gastroenterology. S132-S132. 2020
- The Role of Excess Airway Macrophage Iron on Infective Exacerbations of Chronic Obstructive Pulmonary Disease. American Journal of Respiratory and Critical Care Medicine. 2020
- Phase II trial of cytoreductive stereotactic hypofractionated radiotherapy with combination ipilimumab/nivolumab for metastatic kidney cancer (CYTOSHRINK). Journal of Clinical Oncology. 2020
- Phase II trial of cytoreductive stereotactic hypofractionated radiotherapy with combination ipilimumab/nivolumab for metastatic kidney cancer (CYTOSHRINK).. Journal of Clinical Oncology. TPS761-TPS761. 2020
- Feasibility of the first paediatric randomised controlled pilot trial of faecal microbiota transplant for ulcerative colitis. Journal of Crohn's and Colitis. S353-S354. 2020
- Results of the first paediatric randomised controlled trial of faecal microbiota transplant for ulcerative colitis. Journal of Crohn's and Colitis. S379-S379. 2020
- GENOMIC EPIDEMIOLOGY OF ESCHERICHIA COLI INFECTIONS IN ADULTS WITH CYSTIC FIBROSIS. Pediatric Pulmonology. S308-S308. 2019
- IMPACT OF POTENTIATORS AND CORRECTORS ON GASTROINTESTONAL COMPLICATIONS AND THE MICROBIOME IN CYSTIC FIBROSIS PATIENTS. Pediatric Pulmonology. S141-S142. 2019
- INHALED TOBRAMYCIN'S EFFECT ON THE RESPIRATORY MICROBIOME AND ASSOCIATION WITH CLINICAL RESPONSE IN ADULTS WITH CYSTIC FIBROSIS. Pediatric Pulmonology. S305-S305. 2019
- CRITICAL ROLE OF TOLL-LIKE RECEPTOR 2 IN MEDIATING SEROTONIN PRODUCTION IN GUT. Gastroenterology. S247-S247. 2019
- EPIDEMIOLOGY AND IMPACT OF HAEMOPHILUS INFLUENZAE AIRWAYS INFECTIONS IN ADULTS WITH CYSTIC FIBROSIS. Pediatric Pulmonology. 320-321. 2018
- THE EFFECTS OF AZITHROMYCIN ON THE CYSTIC FIBROSIS MICROBIOME. Pediatric Pulmonology. 313-313. 2018
- MICROBIAL PROTEASES INCREASE SENSITIVITY TO DIETARY ANTIGEN THROUGH PAR-2 SIGNALING. Gastroenterology. S491-S492. 2018
- Epidemiology and natural history ofPseudomonas aeruginosaairway infections in non-cystic fibrosis bronchiectasis. ERJ Open Research. 00162-2017. 2018
- EPIDEMIOLOGY OF STENOTROPHOMONAS MALTOPHILIA INFECTIONS IN ADULTS WITH CYSTIC FIBROSIS (CF): A 30-YEAR SINGLE-CENTRE STUDY. Pediatric Pulmonology. S374-S374. 2017
- MARITIME CYSTIC FIBROSIS NEWBORN SCREENING PROGRAM: AN UPDATE. Pediatric Pulmonology. S409-S410. 2017
- PATTERNS OF PSEUDOMONAS AERUGINOSA LOWER AIRWAYS INFECTIONS AND CLINICAL OUTCOMES IN NON-CYSTIC FIBROSIS BRONCHIECTASIS. Pediatric Pulmonology. S363-S363. 2017
- SPUTUM MICROBIOTA PREDICTS FUTURE CLINICAL OUTCOMES IN CYSTIC FIBROSIS: A COHORT STUDY. Pediatric Pulmonology. S362-S363. 2017
- Activation of Innate Immune Pathways by Bacterial Proteases: Implications for Celiac Disease. Gastroenterology. S71-S71. 2017
- The Microbiome of the Respiratory Tract After Heart Transplantation. The Journal of Heart and Lung Transplantation. S50-S50. 2017
- Abstract # 1849 The role of immune system maturation in development of normal behavior in mice. Brain, Behavior, and Immunity. e39-e39. 2016
- DOES INHALED AZTREONAM LYSINE (AZLI) IMPACT THE CYSTIC FIBROSIS LUNG MICROBIOME?. Pediatric Pulmonology. 306-306. 2016
- EFFECT OF FREEZING SPUTUM ON PSEUDOMONAS AERUGINOSA (PA) POPULATION HETEROGENEITY. Pediatric Pulmonology. 306-307. 2016
- EPIDEMIC PSEUDOMONAS AERUGINOSA: A DRIVING FORCE IN THE CYSTIC FIBROSIS (CF) MICROBIOME?. Pediatric Pulmonology. 330-330. 2016
- Sex Work Alters the Vaginal Microbiome: A Comparison Between Sex Workers and Lower Risk Women from the Same Community in Nairobi, Kenya. AIDS Research and Human Retroviruses. 126-126. 2016
- THE EVOLVING CYSTIC FIBROSIS (CF) MICROBIOME: A LONGITUDINAL COHORT STUDY. Pediatric Pulmonology. 329-330. 2016
- T-cells induced by oral gluten challenge in patients with coeliac disease confirm the in vivo effects of gluten hydrolysed by intestinal bacteria from gnotobiotic mice. European Journal of Immunology. 453-453. 2016
- Multiple Sclerosis Lesions Show Perturbations in Cerebral Microbiota. Neurology. 2016
- Multiple Sclerosis Lesions Show Perturbations in Cerebral Microbiota. Neurology. 2016
- Multiple Sclerosis Lesions Show Perturbations in Cerebral Microbiota. Neurology. 2016
- Multiple Sclerosis Lesions Show Perturbations in Cerebral Microbiota. Neurology. 2016
- Multiple Sclerosis Lesions Show Perturbations in Cerebral Microbiota. Neurology. 2016
- Multiple Sclerosis Lesions Show Perturbations in Cerebral Microbiota. Neurology. 2016
- Multiple Sclerosis Lesions Show Perturbations in Cerebral Microbiota. Neurology. 2016
- 545 Microbiota From an Active Celiac Donor Modulates Intraepithelial Lymphocyte Numbers and Phenotype in the Mouse Small Intestine. Gastroenterology. S114-S114. 2016
- Sa1398 Immunogenic Gluten Is Modulated by Small Intestinal Bacterial Hydrolysis. Gastroenterology. S304-S304. 2016
- Su1891 Colonization of Germ-Free Mice With Human Derived Microbiota Induces Progressive Ultrastructural, Innate, and Functional Changes in the Intestinal Barrier. Gastroenterology. S581-S581. 2016
- Su1897 Inflammation-Related Differences in Mucosa-Associated Microbiota and Paracellular Permeability in Crohn's Colitis. Gastroenterology. S582-S582. 2016
- Su1905 Fecal Microbiome Profiles of Ulcerative Colitis Patients With and Without Anxiety and/or Depression. Gastroenterology. S584-S585. 2016
- Enhanced Culturing Techniques Identify Unexpected Pathogens In Patients With Suspected Ventilator-Associated Infections: The Fast Identification Of Pathogens (findpath) Pilot Study. American Journal of Respiratory and Critical Care Medicine. 2016
- Purpose of the Conference: 2015 Transatlantic Airway Conference. Annals of the American Thoracic Society. S111-S111. 2015
- CHANGES IN THE STRUCTURE OF THE CYSTIC FIBROSIS MICROBIOME THROUGH TIME: A COHORT STUDY. Pediatric Pulmonology. 339-340. 2015
- CULTURE-ENRICHED METAGENOMIC SEQUENCING OF THE CYSTIC FIBROSIS LUNG MICROBIOTA PROVIDES A MORE THOROUGH UNDERSTANDING OF MICROBIAL PROCESSES DURING PULMONARY EXACERBATION. Pediatric Pulmonology. 305-305. 2015
- DEVELOPMENT AND VALIDATION OF A PCR ASSAY TO DETECT THE PRAIRIE EPIDEMIC STRAIN (PES) OF PSEUDOMONAS AERUGINOSA. Pediatric Pulmonology. 337-337. 2015
- DO INHALED ANTIBIOTICS IMPROVE LUNG FUNCTION THROUGH AN EFFECT ON THE CYSTIC FIBROSIS (CF) MICROBIOME?. Pediatric Pulmonology. 330-331. 2015
- LONGITUDINAL SAMPLING OF PATIENTS WITH CYSTIC FIBROSIS INDICATES CHANGES IN THE MICROBIAL COMMUNITY IN THE DAYS PRIOR TO ONSET OF PULMONARY EXACERBATION. Pediatric Pulmonology. 305-305. 2015
- Distinct Roles of the Mucus Layer and Microbiota in Conferring Innate Host Defense and Susceptibility to Disease. The FASEB Journal. 2015
- Fetal and Neonatal Exposure To Nicotine Results in Increased Adiposity: Role of the Gut Microbiome.. Reproductive Sciences. 360A-360A. 2015
- Microbiome Effects on Hematopoietic Eosinophil/Basophil Progenitor Phenotype: Implications for the Pathogenesis of Allergic Inflammation. Journal of Allergy and Clinical Immunology. AB65-AB65. 2015
- The Gut Microbiome in Patients with Anxiety, Depression and Inflammatory Bowel Disease. Neuropsychopharmacology. S289-S289. 2014
- REDUCTION IN P. AERUGINOSA SPUTUM DENSITY DURING A PULMONARY EXACERBATION IN CYSTIC FIBROSIS DOES NOT PREDICT CLINICAL RESPONSE. Pediatric Pulmonology. 250-250. 2014
- A randomized, placebo controlled trial of fecal microbiota therapy in active ulcerative colitis.. Gastroenterology. S159-S159. 2014
- Investigating the microbiome pre and post fecal microbiota therapy from active ulcerative colitis patients in a randomized placebo controlled trial. Gastroenterology. S902-S902. 2014
- The Adoptive Transfer of Anxiety and Gut Dysfunction From IBS Patients to Axenic Mice Through Microbiota Transplantation. Gastroenterology. S845-S845. 2014
- P378 BENEFICIAL EFFECT OF THE PROBIOTIC VSL-3 ON LIVER INJURY-ASSOCIATED SICKNESS BEHAVIOR DEVELOPMENT BY ALTERING SYSTEMIC IMMUNITY AND INHIBITING ACTIVATED MONOCYTES FROM ENTERING THE BRAIN. Journal of Hepatology. S194-S194. 2014
- Specific Crohn's Disease (CD) Associated Risk Alleles Are Associated With the Composition of the Intestinal Microbiota in Healthy First Degree Relatives (FDR) of CD Subjects. Gastroenterology. S57-S57. 2013
- The Relationship Between Common IBD-Associated Risk Alleles and Intestinal Permeability in a Cohort of Healthy First Degree Relatives of Individuals With Crohn's Disease. Gastroenterology. S835-S835. 2013
- alpha-Proteobacteria predominate in the human brain microbiome independent of host immune status. Journal of Neuroimmunology. 137-137. 2012
- Microbial colonization of germ-free mice induces marked change in behaviour that is independent of bacterial diversity. Neurogastroenterology and Motility. 77-77. 2012
- Transfer of IBS phenotype to GERM-free mice through microbiota transplantation. Neurogastroenterology and Motility. 33-33. 2012
- EXPLORING THE STREPTOCOCCUS ANTIBIOTIC RESISTOME IN ADULT CYSTIC FIBROSIS PATIENTS. Pediatric Pulmonology. 323-323. 2011
- MECHANISMS OF ANTIMICROBIAL RESISTANCE IN CYSTIC FIBROSIS AIRWAY ISOLATES OF THE STREPTOCOCCUS MILLERI GROUP. Pediatric Pulmonology. 329-329. 2011
- THE CYSTIC FIBROSIS LUNG MICROBIOME EXPOSES NOVEL MEMBERS OF THE GENUS STREPTOCOCCUS. Pediatric Pulmonology. 325-325. 2010
- CHARACTERIZATION OF STREPTOCOCCUS MILLERI ISOLATES FROM ADULT CYSTIC FIBROSIS PATIENTS. Pediatric Pulmonology. 340-341. 2009
- REAL-TIME PCR ASSAYS FOR DETECTION OF THE STREPTOCOCCUS MILLERI GROUP FROM CF CLINICAL SPECIMENS USING TARGETS FOR CPN60 AND 16S RRNA GENES. Pediatric Pulmonology. 335-335. 2009
- THE CULTURED MICROBIOME OF CYSTIC FIBROSIS AIRWAYS. Pediatric Pulmonology. 313-313. 2009
- WHOLE GENOME SEQUENCING AND COMPARATIVE GENOMIC ANALYSIS OF THE STREPTOCOCCUS MILLERI GROUP. Pediatric Pulmonology. 335-335. 2009
- Escherichea coli Biofilm Formation and Susceptibility in Response to Increased Shear Stresses. ASME 2008 Summer Bioengineering Conference, Parts A and B. 979-980. 2008
- 5-aminosalicylic acid selectivity modulates bacterial gene expression at concentrations which are not inhibitory to growth. Gastroenterology. A712-A712. 2007
- Development of a solid media for the selective isolation of Streptococcus milleri from cystic fibrosis (CF) sputum. Pediatric Pulmonology. 323-324. 2007
- Polymicrobial interactions in CF: Synergies and antagonisms in host response. Pediatric Pulmonology. 150-151. 2007
- The Wavelet Transformation for Temporal Gene Expression Analysis. IEEE Computer Society Conference on Computer Vision and Pattern Recognition Workshops. 148-148. 2005
- Identification of replication sites via a nonparametric method in bacteria. METMBS'03: PROCEEDINGS OF THE INTERNATIONAL CONFERENCE ON MATHEMATICS AND ENGINEERING TECHNIQUES IN MEDICINE AND BIOLOGICAL SCIENCES. 17-21. 2003
- GeneVis: visualization tools for genetic regulatory network dynamics. IEEE Visualization, 2002. VIS 2002.. 243-250. 2002
- Critical Role of Toll-Like Receptor 2 in Mediating Serotonin Production in Gut.. Gastroenterology 2019. S-247-S-247.
- Protective effects of Akkermansia muciniphilia on intestinal barrier function and inflammation.. Journal of the Canadian Association of Gastroenterology 2020. 93-93.
journal articles
- Delivery mode, birth order, and sex impact neonatal microbial colonization.. Gut Microbes. 17:2491667. 2025
- Innate immune system signaling and intestinal dendritic cells migration to the brain underlie behavioral changes after microbial colonization in adult mice.. Brain, Behavior, and Immunity. 127:238-250. 2025
- Genomic characterization of antimicrobial resistance and mobile genetic elements in swine gut bacteria isolated from a Canadian research farm.. Animal Microbiome. 7:66. 2025
- Actinomyces viscosus promotes neuroprotection in C. elegans models of Parkinson's disease.. Mechanisms of Ageing and Development. 225:112061. 2025
- Feasibility and Tolerability of Nabilone for the Treatment of Obesity: A Randomized Controlled Pilot Trial.. Cannabis and Cannabinoid Research. 2025
- Small intestinal microbial fiber metabolism dysfunction in celiac disease.. Res Sq. 2025
- Clinical Remission by a Comprehensive Severe Asthma Management Strategy Guided by Airway Inflammometry and Bioimaging. American Journal of Respiratory and Critical Care Medicine. 211. 2025
- Detecting microbial engraftment after FMT using placebo sequencing and culture enriched metagenomics to sort signals from noise.. Nature Communications. 16:3469. 2025
- Gene-by-environment interactions modulate the infant gut microbiota in asthma and atopy.. Journal of Allergy and Clinical Immunology. S0091-6749(25)00368-9. 2025
- Gut microbiota regulates intestinal goblet cell response and mucin production by influencing the TLR2-SPDEF axis in an enteric parasitic infection.. Mucosal Immunology. S1933-0219(25)00033-9. 2025
- Genomic analysis of the liverpool epidemic strain of pseudomonas aeruginosa infecting persons with cystic fibrosis reveals likely Canadian origins.. Journal of Cystic Fibrosis. S1569-1993(25)00058-X. 2025
- Perturbation of Pseudomonas aeruginosa peptidoglycan recycling by anti-folates and design of a dual-action inhibitor.. mBio. 16:e0298424. 2025
- Food supply toxicants and additives alter the gut microbiota and risk of metabolic disease.. American Journal of Physiology - Endocrinology and Metabolism. 328:E337-E353. 2025
- FECAL PROTEOLYTIC ACTIVITY AND SYMPTOMATIC STATUS ARE ASSOCIATED IN CROHN’S DISEASE. Inflammatory Bowel Diseases. 31:s16-s17. 2025
- A156 FECAL PROTEOLYTIC ACTIVITY IS ASSOCIATED WITH SYMPTOMATIC STATUS IN CROHN’S DISEASE. Journal of the Canadian Association of Gastroenterology. 8:i64-i64. 2025
- A57 SUBOPTIMAL FIBRE CONSUMPTION AND ALTERED FIBRE METABOLISM IN CELIAC DISEASE THROUGHOUT THE GASTROINTESTINAL TRACT. Journal of the Canadian Association of Gastroenterology. 8:i23-i23. 2025
- Early Life Exposure to Parental Crohn's Disease Is Associated With Offspring's Gut Microbiome, Gut Permeability, and Increased Risk of Future Crohn's Disease.. Gastroenterology. 168:385-388.e3. 2025
- FECAL PROTEOLYTIC ACTIVITY AND SYMPTOMATIC STATUS ARE ASSOCIATED IN CROHN’S DISEASE. Gastroenterology. 168:s24. 2025
- The Fem cell-surface signaling system is regulated by ExsA in Pseudomonas aeruginosa and affects pathogenicity.. iScience. 28:111629. 2025
- Healthy First-Degree Relatives From Multiplex Families vs Simplex Families Have Higher Subclinical Intestinal Inflammation, a Distinct Fecal Microbial Signature, and Harbor a Higher Risk of Developing Crohn's Disease.. Gastroenterology. 168:99-110.e2. 2025
- Novel Bifidobacterium Strains Improve Glucose Metabolism and Inflammation in Obese Mice. Canadian Journal of Diabetes. 48:s29. 2024
- Clinical epidemiology and impact of Haemophilus influenzae airway infections in adults with cystic fibrosis.. BMC Infectious Diseases. 24:1209. 2024
- Networks of human milk microbiota are associated with host genomics, childhood asthma, and allergic sensitization.. Cell Host and Microbe. 32:1838-1852.e5. 2024
- Monocyte-driven inflamm-aging reduces intestinal barrier function in females.. Immunity and Ageing. 21:65. 2024
- Microbial colonization programs are structured by breastfeeding and guide healthy respiratory development.. Cell. 187:5431-5452.e20. 2024
- Gluten-Dependent Activation of CD4+ T Cells by MHC Class II–Expressing Epithelium. Gastroenterology. 167:1113-1128. 2024
- Environmental Factors Associated with Risk of Crohn’s Disease Development in the Crohn’s and Colitis Canada - Genetic, Environmental, Microbial Project. Clinical Gastroenterology and Hepatology. 22:1889-1897.e12. 2024
- Su1768 A RANDOMIZED TRIAL OF ANTIMICROBIALS VERSUS PLACEBO IN ADDITION TO FECAL MICROBIOTA TRANSPLANT FOR THE INDUCTION OF REMISSION IN ACTIVE ULCERATIVE COLITIS. Gastroenterology. 166:s-804-s-805. 2024
- Pre-Diagnosis Diet Predicts Response to Exclusive Enteral Nutrition and Correlates with Microbiome in Pediatric Crohn Disease. Nutrients. 16:1033-1033. 2024
- Outcomes Following Acute Severe Colitis at Initial Presentation: A Multi-centre, Prospective, Paediatric Cohort Study. Journal of Crohn's and Colitis. 18:233-245. 2024
- Characteristics of Abdominal Visceral Adipose Tissue, Metabolic Health and the Gut Microbiome in Adults. Journal of Clinical Endocrinology and Metabolism (JCEM). 109:680-690. 2024
- A15 LEVERAGING CULTURE-DEPENDENT AND -INDEPENDENT METAGENOMICS TO IDENTIFY ENTEROBACTERIACEAE GENES ASSOCIATED WITH ACTIVE ULCERATIVE COLITIS. Journal of the Canadian Association of Gastroenterology. 7:8-9. 2024
- A24 AN ULCERATIVE COLITIS-ISOLATED PATHOBIONT CAN DEGRADE MUCUS PRODUCED BY UC PATIENT-DERIVED COLONOIDS. Journal of the Canadian Association of Gastroenterology. 7:13-14. 2024
- Understanding Predictors of Crohn's Disease: Determinants of Altered Barrier Function in Pre-Disease Phase of Crohn's Disease.. Journal of the Canadian Association of Gastroenterology. 7:68-77. 2024
- Human milk oligosaccharides promote intestinal epithelium regeneration independent of the microbiota during necrotizing enterocolitis. Pediatric Surgery International. 40:35. 2024
- The airway microbiome of persons with cystic fibrosis correlates with acquisition and microbiological outcomes of incident Stenotrophomonas maltophilia infection. Frontiers in Microbiology. 15:1353145. 2024
- Alterations in fecal β-defensin-3 secretion as a marker of instability of the gut microbiota. Gut Microbes. 15:2233679. 2023
- Gut microbiota modulates visceral sensitivity through calcitonin gene-related peptide (CGRP) production. Gut Microbes. 15:2188874. 2023
- Parity modulates impact of BMI and gestational weight gain on gut microbiota in human pregnancy. Gut Microbes. 15:2259316. 2023
- Epidemiology and impact of methicillin-sensitive Staphylococcus aureus with β-lactam antibiotic inoculum effects in adults with cystic fibrosis. Antimicrobial Agents and Chemotherapy. 67:e0013623. 2023
- Deep learning-guided discovery of an antibiotic targeting Acinetobacter baumannii. Nature Chemical Biology. 19:1342-1350. 2023
- Associations of intrapartum antibiotics and growth, atopy, gastrointestinal and sleep outcomes at one year of age. Pediatric Research. 94:1026-1034. 2023
- Gut Microbiome Composition Is Associated With Future Onset of Crohn’s Disease in Healthy First-Degree Relatives. Gastroenterology. 165:670-681. 2023
- Gut microbiota promotes stem cell differentiation through macrophage and mesenchymal niches in early postnatal development. Immunity. 56:2175-2175. 2023
- The impact of respiratory infections and probiotic use on the nasal microbiota of frail residents in long-term care homes. ERJ Open Research. 9:00212-2023. 2023
- Postmortem examination of equids >1-year-old with enterotyphlocolitis in Ontario: a retrospective descriptive study. Journal of Veterinary Diagnostic Investigation. 35:350-354. 2023
- Sensitivity to Neutralizing Antibodies and Resistance to Type I Interferons in SARS-CoV-2 R.1 Lineage Variants, Canada. Emerging Infectious Diseases. 29:1386-1396. 2023
- SARS-CoV-2 Outbreak Investigation Using Contact Tracing and Whole-Genome Sequencing in an Ontario Tertiary Care Hospital. Microbiology spectrum. 11:e0190022. 2023
- Definitions, rates and associated mortality of ICU-acquired pneumonia: A multicenter cohort study. Journal of Critical Care. 75:154284-154284. 2023
- Author Correction: Chronic exposure to synthetic food colorant Allura Red AC promotes susceptibility to experimental colitis via intestinal serotonin in mice. Nature Communications. 14:3125. 2023
- Tu1887 EFFECTS OF THE NEXT GENERATION PROBIOTIC, AKKERMANSIA MUCINIPHILA, ON INTESTINAL INFLAMMATION AND BARRIER FUNCTION. Gastroenterology. 164:S-1153. 2023
- Anti-Integrin αvβ6 Autoantibodies Are a Novel Biomarker That Antedate Ulcerative Colitis. Gastroenterology. 164:619-629. 2023
- Effect of dietary iron supplementation on the equine fecal microbiome.. Canadian Journal of Veterinary Research. 87:97-104. 2023
- A267 IDENTIFYING ENTEROBACTERIACEAE VIRULENCE GENES ASSOCIATED WITH ACTIVE DISEASE IN ULCERATIVE COLITIS PATIENTS USING CULTURE-DEPENDENT AND -INDEPENDENT APPROACHES. Journal of the Canadian Association of Gastroenterology. 6:84-85. 2023
- A33 EFFECTS OF THE NEXT GENERATION PROBIOTIC, AKKERMANSIA MUCINIPHILA, ON INTESTINAL INFLAMMATION AND BARRIER FUNCTION. Journal of the Canadian Association of Gastroenterology. 6:18-18. 2023
- A45 FIBER-FREE DIET REDUCES BACTEROIDES ABUNDANCE AND PREVENTS MUCUS DEGRADATION IN MICE COLONIZED WITH MICROBIOTA FROM PATIENTS WITH GENERALIZED ANXIETY DISORDER. Journal of the Canadian Association of Gastroenterology. 6:25-26. 2023
- A8 MICROBIAL ACTIVATION OF INTESTINAL DENDRITIC CELLS IS CRITICAL FOR THE ESTABLISHMENT OF NORMAL BEHAVIOR. Journal of the Canadian Association of Gastroenterology. 6:4-5. 2023
- Human gut microbiota after bariatric surgery alters intestinal morphology and glucose absorption in mice independently of obesity. Gut. 72:460-471. 2023
- Phase II trial of cytoreductive stereotactic hypofractionated radiotherapy with combination ipilimumab/nivolumab for metastatic kidney cancer (CYTOSHRINK).. Journal of Clinical Oncology. 41:TPS750-TPS750. 2023
- Fecal prevalence of Clostridium innocuum DNA in healthy horses and horses with colitis. Anaerobe. 79:102681-102681. 2023
- Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies. Nature. 613:639-649. 2023
- Direct and culture-enriched 16S rRNA sequencing of cecal content of healthy horses and horses with typhlocolitis. PLoS ONE. 18:e0284193-e0284193. 2023
- Stenotrophomonas maltophilia natural history and evolution in the airways of adults with cystic fibrosis. Frontiers in Microbiology. 14:1205389. 2023
- Chronic exposure to synthetic food colorant Allura Red AC promotes susceptibility to experimental colitis via intestinal serotonin in mice. Nature Communications. 13:7617. 2022
- 511. The cefazolin (CZ) and piperacillin-tazobactam (TZP) inoculum effects (IEs) are persistent amongst serial isolates of methicillin-sensitive Staphylococcus aureus (MSSA) derived from the sputum of persons with cystic fibrosis (pwCF) despite variation in other phenotypes.. Open Forum Infectious Diseases. 9:ofac492.567. 2022
- Human Gut Metagenomes Encode Diverse GH156 Sialidases. Applied and Environmental Microbiology. 88:e0175522. 2022
- Gut microbiota promotes stem cell differentiation through macrophage and mesenchymal niches in early postnatal development. Immunity. 55:2300-2317.e6. 2022
- Iron in airway macrophages and infective exacerbations of chronic obstructive pulmonary disease. Respiratory Research. 23:8. 2022
- Biogeographic Variation and Functional Pathways of the Gut Microbiota in Celiac Disease. Gastroenterology. 163:1351-1363.e15. 2022
- Dual Targeting Factors Are Required for LXG Toxin Export by the Bacterial Type VIIb Secretion System. mBio. 13:e0213722. 2022
- The natural history and genetic diversity of Haemophilus influenzae infecting the airways of adults with cystic fibrosis. Scientific Reports. 12:15765. 2022
- Exploring the Cystic Fibrosis Lung Microbiome: Making the Most of a Sticky Situation. Journal of the Pediatric Infectious Diseases Society. 11:S13-S22. 2022
- High-fructose feeding suppresses cold-stimulated brown adipose tissue glucose uptake independently of changes in thermogenesis and the gut microbiome. Cell Reports Medicine. 3:100742-100742. 2022
- Mediterranean-Like Dietary Pattern Associations With Gut Microbiome Composition and Subclinical Gastrointestinal Inflammation. Gastroenterology. 163:685-698. 2022
- Effects of municipal wastewater effluents on the digestive gland microbiome of wild freshwater mussels (Lasmigona costata). Ecotoxicology and Environmental Safety. 241:113774-113774. 2022
- Histamine production by the gut microbiota induces visceral hyperalgesia through histamine 4 receptor signaling in mice. Science Translational Medicine. 14:eabj1895. 2022
- Metformin-induced reductions in tumor growth involves modulation of the gut microbiome. Molecular Metabolism. 61:101498-101498. 2022
- Probe design for simultaneous, targeted capture of diverse metagenomic targets. Cell Reports Methods. 2:100246-100246. 2022
- P122 Identification and characterisation of a Liverpool Epidemic Strain (LES) isolate of Pseudomonas aeruginosa, first collected in 1986 in Calgary, Canada. Journal of Cystic Fibrosis. 21:S98-S98. 2022
- ePS3.09 Methicillin-sensitive Staphylococcus aureus (MSSa) with inoculum-related reduced susceptibility to cefazolin (CZ) and piperacillintazobactam (TZP) in persons with cystic fibrosis (pwCF). Journal of Cystic Fibrosis. 21:S51-S52. 2022
- Colitis-associated microbiota drives changes in behaviour in male mice in the absence of inflammation. Brain, Behavior, and Immunity. 102:266-278. 2022
- A229 GUT MICROBIOTA PROFILES, DIET AND SHORT-CHAIN FATTY ACIDS AS PREDICTORS OF GENERALIZED ANXIETY DISORDER. Journal of the Canadian Association of Gastroenterology. 5:120-121. 2022
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preprints
theses
- The microbiome and immunity in pediatric short bowel syndrome. 2018