Karen Moffat - McMaster Experts

Affiliations

Faculty of Health Sciences, McMaster University
Medicine (Internal), Faculty of Health Sciences
Associate Professor (Part-Time), Medicine, Faculty of Health Sciences
Associate Member, Pathology & Molecular Medicine, Faculty of Health Sciences

Scholarly Activity in McMaster Experts

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chapters
- Platelet Aggregation. 609-626. 2019
- Platelet Aggregation. 619-635. 2017
- Platelet Aggregation. 559-580. 2012
conferences
- Methodology and Systematic Review of the Literature for the Mcmaster RARE-Best Practice Clinical Practice Guideline on Diagnosis and Management of the Catastrophic Antiphospholipid Syndrome. Arthritis & Rheumatology. 2017
- A REGIONAL QUALITY ASSURANCE PROGRAM FOR CORE COAGULATION LABORATORIES-5 YEARS LATER \textbar Request PDF. International Journal of Laboratory Hematology. 14-14. 2013
- FACTOR XIII DIAGNOSTIC TESTING: A RETROSPECTIVE ANALYSIS OF ONE CENTER’S EXPERIENCE. International Journal of Laboratory Hematology. 73-74. 2013
- A review of experiences with external quality assessment challenges for several platelet function disorder assays offered by the North American specialized coagulation laboratory association. Haemophilia. 562-562. 2011
- Bleeding symptoms and risks in undefined bleeding disorders: results from a prospective study. Haemophilia. 562-562. 2011
- An international evaluation of clinical laboratory practices for Lupus anticoagulant testing \textbar Request PDF. Haemophilia. 628-628. 2009
- Application of Levey-Jennings plots to the quality monitoring of platelet aggregation tests \textbar Request PDF. International Journal of Laboratory Hematology. 91-91. 2008
- Pitfalls in interpreting platelet function tests in thrombocytopenic patients referred by a hematologist for diagnostic testing: Results from a single center prospective study.. Blood. 75B-75B. 2005
- Undetected factor VIII level in a type III von Willebrand disease (vWD) patient masquerading as severe hemophilia. Blood. 104B-104B. 2005
- Comparison of 3 assays for the measurement of activated protein C resistance (APCR). Thrombosis and Haemostasis. PS78-PS78. 1997
- A simplified procedure for the establishment of APTT therapeutic ranges for heparin (HEP) therapy. Thrombosis and Haemostasis. 652-652. 1993
journal articles
- Mixing study to diagnose heparin‐resistance caused by functional antithrombin deficiency. International Journal of Laboratory Hematology. 44:e227-e229. 2022
- Ring-Opening Metathesis Polymerization in Miniemulsion Using a TEGylated Ruthenium-Based Metathesis Catalyst. Macromolecules. 51:9088-9096. 2018
- Basic coagulation tests as surrogates of dabigatran levels in a pre-operative setting: Analysis of five activated partial thromboplastin time reagents and thrombin time. Thrombosis Research. 171:62-67. 2018
- Electron microscopy examination of platelet whole mount preparations to quantitate platelet dense granule numbers: Implications for diagnosing suspected platelet function disorders due to dense granule deficiency. International Journal of Laboratory Hematology. 40:400-407. 2018
- McMaster RARE-Bestpractices clinical practice guideline on diagnosis and management of the catastrophic antiphospholipid syndrome. Journal of Thrombosis and Haemostasis. 16:1656-1664. 2018
- Laboratory Monitoring of Oral Vitamin K Anticoagulation. Seminars in Thrombosis and Hemostasis. 43:245-252. 2017
- Variability in platelet dense granule adenosine triphosphate release findings amongst patients tested multiple times as part of an assessment for a bleeding disorder. International Journal of Laboratory Hematology. 38:648-657. 2016
- Report on the International Society for Laboratory Hematology Survey on guidelines to support clinical hematology laboratory practice. International Journal of Laboratory Hematology. 38:133-138. 2016
- Effect of standardized perioperative dabigatran interruption on the residual anticoagulation effect at the time of surgery or procedure. Journal of Thrombosis and Haemostasis. 14:89-97. 2016
- Internal Quality Control Practices in Coagulation Laboratories: recommendations based on a patterns‐of‐practice survey. International Journal of Laboratory Hematology. 37:729-738. 2015
- Hemodialysis for the treatment of dabigatran‐associated bleeding: a case report and systematic review. Journal of Thrombosis and Haemostasis. 13:1790-1798. 2015
- Assembly and evaluation of an inventory of guidelines that are available to support clinical hematology laboratory practice. International Journal of Laboratory Hematology. 37:36-45. 2015
- Monitoring the anticoagulant effect after a massive rivaroxaban overdose. Journal of Thrombosis and Haemostasis. 12:1570-1571. 2014
- Evaluation of an automated method for measuring von Willebrand factor activity in clinical samples without ristocetin. International Journal of Laboratory Hematology. 36:341-351. 2014
- Technological advances in diagnostic testing for von Willebrand disease: new approaches and challenges. International Journal of Laboratory Hematology. 36:334-340. 2014
- Laboratory testing for bleeding disorders: strategic uses of high and low‐yield tests. International Journal of Laboratory Hematology. 35:322-333. 2013
- Anticardiolipin Antibody and Anti-beta 2 Glycoprotein I Antibody Assays. Methods in molecular biology (Clifton, N.J.). 992:387-405. 2013
- Lupus Anticoagulant Testing. Methods in molecular biology (Clifton, N.J.). 992:97-108. 2013
- Multi-scale modeling and synthesis of polyester ionomers. Physical Chemistry, Chemical Physics - PCCP. 15:6128-6128. 2013
- Platelet Aggregation. Platelets. 559-580. 2013
- Laboratory Investigations for Bleeding Disorders. Seminars in Thrombosis and Hemostasis. 38:742-752. 2012
- External Quality Assessment of Platelet Disorder Investigations: Results of International Surveys on Diagnostic Tests for Dense Granule Deficiency and Platelet Aggregometry Interpretation. Seminars in Thrombosis and Hemostasis. 38:622-631. 2012
- Approaches to investigating common bleeding disorders: An evaluation of North American coagulation laboratory practices. American Journal of Hematology. 87:S45-S50. 2012
- Simultaneous measurement of adenosine triphosphate release and aggregation potentiates human platelet aggregation responses for some subjects, including persons with Quebec platelet disorder. Thrombosis and Haemostasis. 107:726-734. 2012
- Critical Values in the Coagulation Laboratory Results of a Survey of the North American Specialized Coagulation Laboratory Association. American Journal of Clinical Pathology. 136:836-41. 2011
- Diagnostic Usefulness of a Lumi-Aggregometer Adenosine Triphosphate Release Assay for the Assessment of Platelet Function Disorders. American Journal of Clinical Pathology. 136:350-358. 2011
- A prospective cohort study of light transmission platelet aggregometry for bleeding disorders: Is testing native platelet-rich plasma non-inferior to testing platelet count adjusted samples?. Thrombosis and Haemostasis. 106:675-682. 2011
- Development of North American Consensus Guidelines for Medical Laboratories That Perform and Interpret Platelet Function Testing Using Light Transmission Aggregometry. American Journal of Clinical Pathology. 134:955-963. 2010
- Interlaboratory variation in heparin monitoring: Lessons from the Quality Management Program of Ontario coagulation surveys. Thrombosis and Haemostasis. 104:837-844. 2010
- Undetected factor VIII in a patient with type 3 von Willebrands disease mistaken as severe haemophilia A. Haemophilia. 15:1258-1261. 2009
- Results of a worldwide survey on the assessment of platelet function by light transmission aggregometry: a report from the platelet physiology subcommittee of the SSC of the ISTH. Journal of Thrombosis and Haemostasis. 7:1029-1029. 2009
- Results of an External Proficiency Testing Exercise on Platelet Dense-Granule Deficiency Testing by Whole Mount Electron Microscopy. American Journal of Clinical Pathology. 131:671-675. 2009
- Diagnostic utility of light transmission platelet aggregometry: results from a prospective study of individuals referred for bleeding disorder assessments. Journal of Thrombosis and Haemostasis. 7:676-684. 2009
- Are laboratories following published recommendations for lupus anticoagulant testing?. Thrombosis and Haemostasis. 101:178-184. 2009
- the interpretation of light transmittance platelet aggregation is inconsistent-results from an international challenge: Oc-mo-134. Journal of Thrombosis and Haemostasis. 7:159-159. 2009
- Laboratory testing for fibrinogen abnormalities. American Journal of Hematology. 83:928-931. 2008
- Laboratory issues in bleeding disorders. Haemophilia. 14:93-103. 2008
- An evaluation of methods for determining reference intervals for light transmission platelet aggregation tests on samples with normal or reduced platelet counts. Thrombosis and Haemostasis. 100:01-12. 2008
- NASCOLA SURVEY OF HIT TESTING IN NORTH AMERICA. Journal of Thrombosis and Haemostasis. 5:p-m-336-p-m-336. 2007
- Laboratory testing for heparin-induced thrombocytopenia is inconsistent in North America: A survey of North American specialized coagulation laboratories. Thrombosis and Haemostasis. 98:1357-1361. 2007
- Prophylactic and perioperative replacement therapy for acquired factor XIII deficiency: reply to a rebuttal. Journal of Thrombosis and Haemostasis. 3:187-188. 2005
- Variability in clinical laboratory practice in testing for disorders of platelet function. Thrombosis and Haemostasis. 93:549-553. 2005
- Prophylactic and perioperative replacement therapy for acquired factor XIII deficiency. Journal of Thrombosis and Haemostasis. 2:1017-1019. 2004
- Stable Free Radical Polymerization Process: Kinetic and Mechanistic Study of the Thermal Decomposition of MB-TMP Monitored by NMR and ESR Spectroscopy. Macromolecules. 32:1004-1012. 1999
- Effect of Warfarin on Activated Partial Thromboplastin Time in Patients Receiving Heparin. JAMA Internal Medicine. 158:1140-1140. 1998
- Comparison of 5-mg and 10-mg Loading Doses in Initiation of Warfarin Therapy. ACP journal club. 126:133-133. 1997
- Reliability of the international normalized ratio for monitoring the induction phase of warfarin: Comparison with the prothrombin time ratio. Translational Research. 128:214-217. 1996
- Stable free radical polymerization of styrene using a combined initiator reversible terminating agent. Papers presented at the ... meeting. American Chemical Society. Division of Polymer Chemistry. 37:509-510. 1996
- Evaluation of a Soluble Fibrin Assay in Patients with Suspected Pulmonary Embolism. Thrombosis and Haemostasis. 75:551-554. 1996
- Antiphospholipid antibodies and venous thromboembolism. Blood. 86:3685-3691. 1995
- Evaluation of a soluble fibrin assay in patients with suspected deep vein thrombosis.. Thrombosis and Haemostasis. 74:833-836. 1995
- Free-Radical Polymerization for Narrow-Polydispersity Resins. Semiempirical Molecular Orbital Calculations as a Criterion for Selecting Stable Free-Radical Reversible Terminators. Macromolecules. 28:1841-1846. 1995
- Evaluation of a Soluble Fibrin Assay in Patients with Suspected Deep Vein Thrombosis. Thrombosis and Haemostasis. 74:833-836. 1995
- ChemInform Abstract: NMR STUDIES OF NICKEL HYDRIDES: THE INTRAMOLECULAR REARRANGEMENT OF THE HYDRIDOTRIS(TRI‐P‐TOLYL PHOSPHITE)NICKEL(II) ION. ChemInform. 16:no-no. 1985
- NMR studies of nickel hydrides: the intramolecular rearrangement of the hydridotris(tri-p-tolyl phosphite)nickel(II) ion. Journal of the American Chemical Society. 106:8110-8116. 1984
- GENDER DIFFERENCES IN BLEEDING PROBLEMS AND IMPLICATIONS FOR THE ASSESSMENT OF A BLEEDING DISORDER. Clinical and Investigative Medicine. 31:18-18.
- WHAT’S IN A VALIDATION? REQUIREMENTS AND RECOMMENDATIONS THAT CLINICAL HEMATOLOGY LABORATORIES SHOULD CONSIDER. International Journal of Laboratory Hematology. 35:29-29.
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