selected scholarly activity
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chapters
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conferences
- Lung Cancer in a Steel Foundry. Chest. 313S-313S. 1986
- FRACTIONATION AND IDENTIFICATION OF POLYCYCLIC AROMATIC COMPOUNDS IN MUTAGENIC EXTRACTS OF STEEL FOUNDRY PARTICULATES.. Annual Conference on Mass Spectrometry and Allied Topics. 279-280. 1984
- METABOLISM OF NITRATED POLYCYCLIC AROMATIC HYDROCARBONS AND FORMATION OF DNA-ADDUCTS IN SALMONELLA TYPHIMURIUM.. Polynuclear Aromatic Hydrocarbons, International Symposium. 89-98. 1983
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journal articles
- The influence of local DNA sequence and DNA repair background on the mutational specificity of 1-nitroso-8-nitropyrene in Escherichia coli: inferences for mutagenic mechanisms.. Genetics. 132:911-927. 1992
- The action of 1-nitroso-8-nitroprene in Eachericia coli: DNA adduct formation and mutational consequeces in the absence of necleotide excision-repair. Carcinogenesis. 12:879-884. 1991
- The mutational specificity of 2-(2-furyl)-3-(5-nitro-2-furyl)-acrylamide (AF2) in the lacI gene of Escherichia coli. Carcinogenesis. 12:29-34. 1991
- Comparison of in vivo somatic cell mutation, chromosome aberration, sister chromatid exchange, micronuclei formation and urine mutagenicity in steel foundry workers.. Progress in Clinical and Biological Research. 340C:377-386. 1990
- Comparison of three assays for genetic effects of antineoplastic drugs on cancer patients and their nurses. Environmental and Molecular Mutagenesis. 15:83-92. 1990
- Formation and persistence of DNA adducts in rats following intraperitoneal administration of 1,8-dinitropyrene. Carcinogenesis. 11:1037-1040. 1990
- Proposed Plan for a Unified Approach for Evaluating Nitrofuran Residues. Drug Metabolism Reviews. 22:863-869. 1990
- SHORT COMMUNICATION: DNA adduct formation in primary rabbit tracheal epithelial cells following treatment with 1, 8-dinitropyrene and its partially reduced derivative, 1-nitro-8-nitrosopyrene. Carcinogenesis. 10:1323-1327. 1989
- Identification of the photolysis products of nitrofurazone irradiated with laboratory illumination. Canadian Journal of Chemistry. 65:1128-1132. 1987
- Etoposide (VP16) and teniposide (VM26): novel anticancer drugs, strongly mutagenic in mammalian but not prokaryotic test systems. Mutagenesis. 2:179-186. 1987
- Metabolic activation of 3-nitroperylene in the Salmonella/S9 assay. Mutagenesis. 2:279-285. 1987
- The Mutagenicity of Emissions From Eight Binder Systems Used in Steel Foundries. AIHA journal : a journal for the science of occupational and environmental health and safety. 47:578-586. 1986
- Identification of the DNA adduct formed by metabolism of 1,8-dinitropyrene in Salmonella typhimurium. Carcinogenesis. 7:105-110. 1986
- Metabolism and mutagenesis of benzidine in Salmonella typhimurium strains TA98 and TA98/1,8-DNP6. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS. 144:159-163. 1985
- Identification of polycyclic aromatic compounds in mutagenic emissions from steel casting. Journal of Mass Spectrometry. 12:143-150. 1985
- Dinitropyrene-resistant Salmonella typhimurium are deficient in an acetyl-CoA acetyltransferase. Chemico-Biological Interactions. 54:281-288. 1985
- Metabolism of 1,8-dinitropyrene by Salmonella typhimurium. Chemico-Biological Interactions. 49:351-368. 1984
- Aerobic reduction of 5-nitro-2-furaldehyde semicarbazone by rat liver xanthine dehydrogenase. Biochemical Pharmacology. 33:799-805. 1984
- Lung cancer in a steel foundry: a search for causation.. Journal of Occupational and Environmental Medicine. 25:573-578. 1983
- Distribution of extractable mutagenic activity in steel foundry air particulates of different sizes. Environmental Mutagenesis. 5:881-889. 1983
- Mutagenicity of nitrofuran derivatives: Review. Environmental Mutagenesis. 5:745-765. 1983
- The 1-nitropyrene reductase of Salmonella typhimurium. Chemico-Biological Interactions. 43:67-71. 1983
- Amaranth suppresses the mutagenicity of 2-acetylaminofluorene by lowering the concentration of nadph in top agar. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS. 82:201-211. 1981
- Metabolism of 1-nitropyrene and formation of DNA adducts in Salmonella typhimurium. Carcinogenesis. 2:1007-1011. 1981
- Type I nitroreductases of Escherichia coli. Canadian Journal of Microbiology. 27:81-86. 1981
- Formation and excision of nitrofuran-DNA adducts in Escherichia coli. Chemico-Biological Interactions. 31:133-150. 1980
- Nitrofuran induced mutagenesis and error prone repair in Escherichia coli. Chemico-Biological Interactions. 31:151-166. 1980
- Action of Nitrofurans on E. Coli. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS. 67:133-144. 1979
- Action of some nitrofuran derivatives on glucose metabolism, ATP levels, and macromolecule synthesis in Escherichia coli. Canadian Journal of Microbiology. 24:650-657. 1978
- The action of AF 2 on cultured hamster and human cells under aerobic and hypoxic conditions. Chemico-Biological Interactions. 21:89-102. 1978
- Genetics of Nitrofurazone Resistance in Escherichia coli. Journal of Bacteriology. 133:10-16. 1978
- Chloramphenicol damages bacterial DNA. Biochemical and Biophysical Research Communications. 78:151-157. 1977
- Use of a simplified fluctuation test to detect and characterize mutagenesis by nitrofurans.. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS. 44:139-143. 1977
- Cytotoxicity and DNA damage to mammalian cells by nitrofurans. Chemico-Biological Interactions. 16:223-233. 1977
- Biological effects of nitrofurans. Journal of Antimicrobial Chemotherapy. 3:517-520. 1977
- Effect of nitrofurazone on bacterial RNA and ribosome synthesis and on the function of ribosomes. Chemico-Biological Interactions. 14:81-91. 1976
- Nitrofurazone-reducing enzymes in E. coli and their role in drug activation in vivo. Canadian Journal of Microbiology. 21:1484-1491. 1975
- Effect of activated nitrofurans on DNA. Biochimica et Biophysica Acta: international journal of biochemistry and biophysics. 402:142-149. 1975
- Mutagen screening with bacteria: Niridazole and nitrofurans. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS. 31:31-37. 1975
- Nitrofuran‐Reducing Enzymes of Euglena*. Journal of Eukaryotic Microbiology. 22:130-134. 1975
- On the mutagenicity of nitrofurans. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS. 26:3-16. 1974
- Nitrofurans as radiosensitizers of hypoxic mammalian cells.. Cancer Research. 32:2616-2624. 1972
- Breakage of bacterial DNA by nitrofuran derivatives.. Cancer Research. 31:2184-2188. 1971
- “Activation” of nitrofurazone in animal tissues. Biochemical Pharmacology. 20:3532-3537. 1971
- Mode of Action of Nitrofurazone. Journal of Bacteriology. 104:1126-1134. 1970
- Action of Nitrofuran Derivatives on the Chloroplast System of Euglena gracilis: Effect of Light. Journal of Eukaryotic Microbiology. 17:129-134. 1970
- Action of Myxin on the Chloroplast System of Euglena gracilis. Journal of Eukaryotic Microbiology. 16:425-428. 1969
- Excision of 7-methylguanine from the DNA of Euglena gracilis. Biochimica et Biophysica Acta: international journal of biochemistry and biophysics. 186:229-231. 1969
- Reaction of N-methyl-N'-nitro-N-nitrosoguanidine with protein: formation of nitroguanido derivatives.. Biochemistry and Cell Biology. 46:1410-1415. 1968
- Inactivation of biologically active N-methyl-N-nitroso compounds in aqueous solution: effect of various conditions of pH and illumination.. Biochemistry and Cell Biology. 46:807-811. 1968
- A simple method for the isolation of fraction I protein of chloroplasts.. Biochemistry and Cell Biology. 46:441-444. 1968
- Reaction of and with DNA in vitro. Biochimica et Biophysica Acta: international journal of biochemistry and biophysics. 155:114-120. 1968
- Inhibition of Euglena macromolecule synthesis by N-methyl-N-nitro-N-nitrosoguanidine and N-methyl-N-nitroso-p-toluenesulfonamide.. Biochemistry and Cell Biology. 45:1357-1363. 1967
- Mutation of the Euglena Chloroplast System: The Mechanism of Bleaching by Nitrosoguanidine and Related Compounds. Journal of Eukaryotic Microbiology. 14:480-482. 1967
- Isolation and properties of a Euglena mutant resistant to the killing and bleaching effects of N-methyl-N′-nitro-N-nitrosoguanidine and some other agents. Biochimica et Biophysica Acta: international journal of biochemistry and biophysics. 142:219-227. 1967
- Action of Some Analogs of Nitrosoguanidine on the Chloroplasts of Euglena gracilis. Journal of Eukaryotic Microbiology. 13:472-474. 1966
- Prophage induction by N-methyl-N'-nitro-N-nitrosoguanidine.. Canadian Journal of Microbiology. 12:202-204. 1966
- Chloroplast Mutagenesis: Effect of N -Methyl- N ′-Nitro- N -Nitrosoguanidine and Some Other Agents on Euglena. Science. 148:497-499. 1965
- NITROFURAN DERIVATIVES AS RADIOMIMETIC AGENTS: CROSS-RESISTANCE STUDIES WITH ESCHERICHIA COLI.. Canadian Journal of Microbiology. 11:185-191. 1965
- Effect of Nitrofurans on the Chloroplast System of Euglena gracilis. Journal of Eukaryotic Microbiology. 12:34-41. 1965
- EFFECTS OF SOME NITROFURANS ON DNA SYNTHESIS AND PROPHAGE INDUCTION.. Biochemistry and Cell Biology. 42:1245-1247. 1964
- Effect of Actinomycin D on Euglena Chloroplast Formation. Nature. 201:504-505. 1964
- Accumulation of Extracellular Amino Acids by Euglena gracilis. Journal of Eukaryotic Microbiology. 10:491-495. 1963
- Chloroplasts of Euglena gracilis Affected by Furadantin. Science. 137:225-226. 1962
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theses
- Damage to mammalian cell DNA by nitrofurans.. Cancer Research. 1975