Benzo(a)pyrene Concept

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• In vitro exposure to cigarette smoke induces oxidative stress in follicular cells of F₁ hybrid mice  Journal Articles
• Aryl hydrocarbon receptor antagonists attenuate the deleterious effects of benzo[a]pyrene on isolated rat follicle development  Journal Articles
• Benzo-[a]-pyrene increases invasion in MDA-MB-231 breast cancer cells via increased COX-II expression and prostaglandin E2 (PGE2) output  Journal Articles
• Cigarette smoke causes follicle loss in mice ovaries at concentrations representative of human exposure  Journal Articles
• Effect of Environmental Contaminants on Beta Cell Function  Journal Articles
• Effect of in vitro exposure to benzo[a]pyrene, a component of cigarette smoke, on folliculogenesis, steroidogenesis and oocyte nuclear maturation  Journal Articles
• Enhanced proliferation of cells from human tissue explants following irradiation in the presence of environmental carcinogens  Journal Articles
• Follicle growth is inhibited by benzo-[a]-pyrene, at concentrations representative of human exposure, in an isolated rat follicle culture assay  Journal Articles
• Functional differences in the cytochrome P450 1 family enzymes from Zebrafish (Danio rerio) using heterologously expressed proteins  Journal Articles
• Induction and substrate specificity of the lanosterol 14 alpha-demethylase from Saccharomyces cerevisiae Y222  Journal Articles
• Microsatellite DNA Mutations in Double-Crested Cormorants (Phalacrocorax auritus) Associated with Exposure to PAH-Containing Industrial Air Pollution  Journal Articles
• Quantification of benzo[a]pyrene and other PAHs in the serum and follicular fluid of smokers versus non-smokers  Journal Articles
• Rainbow trout exposed to benzo[a]pyrene yields conserved microRNA binding sites in DNA methyltransferases across 500 million years of evolution  Journal Articles
• Resveratrol, a natural aryl hydrocarbon receptor antagonist, protects lung from DNA damage and apoptosis caused by benzo[a]pyrene  Journal Articles
• Resveratrol, a natural aryl hydrocarbon receptor antagonist, protects sperm from DNA damage and apoptosis caused by benzo(a)pyrene  Journal Articles
• Screening for DNA adducts in ovarian follicles exposed to benzo[a]pyrene and cigarette smoke condensate using liquid chromatography-tandem mass spectrometry  Journal Articles
• The cigarette smoke constituent benzo[a]pyrene disrupts metabolic enzyme, and apoptosis pathway member gene expression in ovarian follicles  Journal Articles
• The effects of copper and benzo[a]pyrene on retinoids and reproduction in zebrafish  Journal Articles
• Zebrafish CYP1A expression in transgenic Caenorhabditis elegans protects from exposures to benzo[a]pyrene and a complex polycyclic aromatic hydrocarbon mixture  Journal Articles