Journal article
Enhanced transepithelial antigen transport in intestine of allergic mice is mediated by IgE/CD23 and regulated by interleukin-4
Abstract
BACKGROUND & AIMS: We previously described a system for enhanced transepithelial transport of antigen in which both the amount of specific antigen and its rate of transport were dramatically increased in intestine of sensitized rats compared with controls. This study investigated the essential components mediating antigen uptake in mice genetically deficient for interleukin (IL)-4 or CD23.
METHODS: Mice were actively or passively sensitized to …
Authors
Yu LCH; Yang P-C; Berin MC; Di Leo V; Conrad DH; Mckay DM; Satoskar AR; Perdue MH
Journal
Gastroenterology, Vol. 121, No. 2, pp. 370–381
Publisher
Elsevier
Publication Date
8 2001
DOI
10.1053/gast.2001.26470
ISSN
0016-5085