selected scholarly activity
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chapters
- Venous Thromboembolic Disease. 1032-1049. 2009
- Venous Thromboembolism. 135-146. 2009
- Diagnosis of Deep Vein Thrombosis. 47-55. 2008
- Emerging oral antiplatelet receptor inhibitors. 119-126. 2008
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conferences
- Autoimmune HIT due to apheresis catheter heparin flushes for stem cell harvesting before autotransplantation for myeloma. Blood. 1679-1682. 2017
- Bleeding in Patients Receiving Low-Molecular-Weight Heparin for Cancer-Associated Thrombosis. Blood. 1120-1120. 2015
- Outcomes of Low-Molecular-Weight Heparintreatment for Venous Thromboembolism in Patients with Primary and Metastatic Brain Tumors. Blood. 428-428. 2015
- Rivaroxaban for Treatment of Suspected or Confirmed Heparin-Induced Thrombocytopenia Study. Blood. 3468-3468. 2015
- A Canadian consensus on venous thromboembolism (VTE) prophylaxis prevention in thoracic surgery, a national Delphi consensus survey. Journal of Thrombosis and Haemostasis. 486-487. 2015
- Combination Of 4T’s Score and Rapid Gel Centrifugation Assay Excludes HIT In a Prospective Cohort Study. Blood. 3535-3535. 2013
- Thrombotic events in metastatic colorectal cancer patients treated with FOLFIRI plus bevacizumab.. Journal of Clinical Oncology. 2013
- Thrombotic events in patients with metastatic colorectal cancer treated with FOLFIRI plus bevacizumab.. Journal of Clinical Oncology. 540-540. 2013
- Positive Predictive Value of Progressively Elevated D-Dimer Levels in Patients with a Suspected First Deep Vein Thrombosis.. Blood. 2258-2258. 2012
- Factor Xa or thrombin: Is thrombin a better target?. Journal of Thrombosis and Haemostasis. 65-67. 2007
- Role of Gender in the Clinical Presentation of a First Deep Venous Thrombosis (DVT) in Outpatients.. Blood. 1478-1478. 2006
- New anticoagulants. Journal of Thrombosis and Haemostasis. 1843-1853. 2005
- Case-fatality for major bleeding and intracranial hemorrhage in patients with venous thromboembolism on long-term oral anticoagulant therapy: A systematic review.. Blood. 705A-705A. 2002
- Interobserver agreement on ultrasound measurements of thrombus diameter and length: Derivation of criteria for the diagnosis of recurrent deep vein thrombosis.. Blood. 275A-275A. 2002
- Reduction of out-of-hospital symptomatic venous thromboembolism by extended thromboprophylaxis with low molecular weight heparin following elective hip arthroplasty. A systematic review.. Blood. 703A-703A. 2002
- Ultrasound measurement of thrombus cross-sectional area instead of thrombus diameter: A better way to diagnose recurrent deep vein thrombosis.. Blood. 275A-275A. 2002
- In vitro comparison of the effect of heparin, low-molecular-weight heparin and pentasaccharide on tests of coagulation.. Blood. 45A-45A. 2001
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journal articles
- Boosting efficiency in a clinical literature surveillance system with LightGBM.. PLOS Digital Health. 3:e0000299. 2024
- The McMaster Health Information Research Unit: Over a Quarter-Century of Health Informatics Supporting Evidence-Based Medicine. Journal of Medical Internet Research. 26:e58764-e58764. 2024
- Protocol for a living evidence synthesis on variants of concern and COVID-19 vaccine effectiveness. Vaccine. 41:6411-6418. 2023
- Deep learning to refine the identification of high-quality clinical research articles from the biomedical literature: Performance evaluation. Journal of Biomedical Informatics. 142:104384-104384. 2023
- Joint 2022 European Society of Thoracic Surgeons and The American Association for Thoracic Surgery guidelines for the prevention of cancer-associated venous thromboembolism in thoracic surgery. Journal of Thoracic and Cardiovascular Surgery. 165:794-824.e6. 2023
- Joint 2022 European Society of Thoracic Surgeons and The American Association for Thoracic Surgery guidelines for the prevention of cancer-associated venous thromboembolism in thoracic surgery. European Journal of Cardio-thoracic Surgery. 63:ezac488. 2022
- Extended reporting guidance for vaccine effectiveness studies for variants of concern for COVID-19. Vaccine. 40:2986-2987. 2022
- Evaluating compliance of extended venous thromboembolism prophylaxis following abdominopelvic surgery for cancer: A multidisciplinary quality improvement project. Journal of Surgical Oncology. 125:437-447. 2022
- A Deep Learning Approach to Refine the Identification of High-Quality Clinical Research Articles From the Biomedical Literature: Protocol for Algorithm Development and Validation. JMIR Research Protocols. 10:e29398-e29398. 2021
- Posthospital discharge venous thromboembolism prophylaxis among colorectal and hepatobiliary surgeons: A practice survey. Surgery. 170:173-179. 2021
- Challenging anticoagulation cases: A case of acute pulmonary embolism in a patient with chronic thrombocytopenia. Thrombosis Research. 198:83-85. 2021
- Double Blind Pilot Randomized Trial Comparing Extended Anticoagulation to Placebo Following Major Lung Resection for Cancer. Seminars in Thoracic and Cardiovascular Surgery. 33:1123-1134. 2021
- Management of heparin-induced thrombocytopenia: systematic reviews and meta-analyses. Blood Advances. 4:5184-5193. 2020
- Adverse outcomes associated with managing suspected heparin induced thrombocytopenia in the critically ill. Thrombosis Research. 193:218-220. 2020
- Maximum 24‐hour platelet count fall: Metric for improving the diagnosis of heparin‐induced thrombocytopenia among patients with intermediate probability 4Ts scores. Journal of Thrombosis and Haemostasis. 18:2018-2024. 2020
- International Delphi survey of the ESTS/AATS/ISTH task force on venous thromboembolism prophylaxis in thoracic surgery: the role of extended post-discharge prophylaxis. European Journal of Cardio-thoracic Surgery. 57:854-859. 2020
- Venous thromboembolism prophylaxis in thoracic surgery patients: an international survey. European Journal of Cardio-thoracic Surgery. 57:331-337. 2020
- Shelly, MAiD and the purple parade. CANADIAN MEDICAL ASSOCIATION JOURNAL. 191:E668-E669. 2019
- Edoxaban is non-inferior to low-molecular-weight heparin for treating cancer-associated venous thromboembolism. BMJ Evidence-Based Medicine. 23:230-230. 2018
- American Society of Hematology 2018 guidelines for management of venous thromboembolism: heparin-induced thrombocytopenia. Blood Advances. 2:3360-3392. 2018
- Systematic review of fondaparinux for heparin‐induced thrombocytopenia: When there are no randomized controlled trials. Research and Practice in Thrombosis and Haemostasis. 2:678-683. 2018
- Venous Thromboembolic Events Following Major Pelvic and Abdominal Surgeries for Cancer: A Prospective Cohort Study. Annals of Surgical Oncology. 25:3214-3221. 2018
- High sensitivity and specificity of an automated IgG-specific chemiluminescence immunoassay for diagnosis of HIT. Blood. 132:1345-1349. 2018
- Rivaroxaban for Thromboprophylaxis after Hospitalization for Medical Illness. New England Journal of Medicine. 379:1118-1127. 2018
- Questioning the use of an age‐adjusted D‐dimer threshold to exclude venous thromboembolism: reply. Journal of Thrombosis and Haemostasis. 16:1448-1450. 2018
- Management of cancer-associated upper extremity deep vein thrombosis with and without venous catheters at a tertiary care center. Thrombosis Research. 166:92-95. 2018
- Direct oral anticoagulants for treatment of HIT: update of Hamilton experience and literature review. Blood. 130:1104-1113. 2017
- Performance characteristics of an automated latex immunoturbidimetric assay [HemosIL ® HIT-Ab (PF4-H) ] for the diagnosis of immune heparin-induced thrombocytopenia. Thrombosis Research. 153:108-117. 2017
- Review of D‐dimer testing: Good, Bad, and Ugly. International Journal of Laboratory Hematology. 39:98-103. 2017
- Comparison of clinical probability-adjusted D-dimer and age-adjusted D-dimer interpretation to exclude venous thromboembolism. Thrombosis and Haemostasis. 117:1937-1943. 2017
- Outcomes of low-molecular-weight heparin treatment for venous thromboembolism in patients with primary and metastatic brain tumours. Thrombosis and Haemostasis. 117:589-594. 2017
- Practice patterns in venous thromboembolism (VTE) prophylaxis in thoracic surgery: a comprehensive Canadian Delphi survey. Journal of Thoracic Disease. 9:80-87. 2017
- Questioning the use of an age‐adjusted D‐dimer threshold to exclude venous thromboembolism: analysis of individual patient data from two diagnostic studies: reply. Journal of Thrombosis and Haemostasis. 14:2555-2556. 2016
- Questioning the use of an age‐adjusted D‐dimer threshold to exclude venous thromboembolism: analysis of individual patient data from two diagnostic studies. Journal of Thrombosis and Haemostasis. 14:1953-1959. 2016
- Rivaroxaban for treatment of suspected or confirmed heparin‐induced thrombocytopenia study. Journal of Thrombosis and Haemostasis. 14:1206-1210. 2016
- End of the road for heparin thromboprophylaxis. Blood. 127:1945-1946. 2016
- Postdischarge venous thromboembolic complications following pulmonary oncologic resection: An underdetected problem. Journal of Thoracic and Cardiovascular Surgery. 151:992-999. 2016
- Rapid quantitative D‐dimer to exclude pulmonary embolism: a prospective cohort management study. Journal of Thrombosis and Haemostasis. 14:504-509. 2016
- Reproducibility of Pretest Assessment in Suspected Pulmonary Embolism. Laboratory Medicine. 39:361-364. 2015
- Combination of 4Ts score and PF4/H-PaGIA for diagnosis and management of heparin-induced thrombocytopenia: prospective cohort study. Blood. 126:597-603. 2015
- Recurrent venous thromboembolism in anticoagulated patients with cancer: management and short-term prognosis. Journal of Thrombosis and Haemostasis. 13:1010-1018. 2015
- Thrombotic events in metastatic colorectal cancer patients treated with leucovorin, fluorouracil and irinotican (FOLFIRI) plus bevacizumab.. Journal of Gastrointestinal Oncology. 6:274-279. 2015
- Case-fatality of recurrent venous thromboembolism and major bleeding associated with aspirin, warfarin, and direct oral anticoagulants for secondary prevention. Thrombosis Research. 135:243-248. 2015
- Heparin-Induced Thrombocytopenia Presenting as Bilateral Adrenal Hemorrhages. New England Journal of Medicine. 372:492-494. 2015
- Heparin induced thrombocytopenia. The BMJ. 350:g7566-g7566. 2015
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d -Dimer Testing to Select Patients With a First Unprovoked Venous Thromboembolism Who Can Stop Anticoagulant Therapy. ACP journal club. 162:27-34. 2015 - Rivaroxaban for treatment of HIT: A riveting first experience. Thrombosis Research. 135:1-2. 2015
- Design of the rivaroxaban for heparin-induced thrombocytopenia study. Journal of Thrombosis and Thrombolysis. 38:485-492. 2014
- Monitoring the anticoagulant effect after a massive rivaroxaban overdose. Journal of Thrombosis and Haemostasis. 12:1570-1571. 2014
- Venous Thromboembolism in Older Adults: A Community-based Study. American Journal of Medicine. 127:530-537.e3. 2014
- Bleeding risks associated with vitamin K antagonists. Blood Reviews. 27:111-118. 2013
- American College of Chest Physicians Guidelines for Heparin-Induced Thrombocytopenia: Response. Chest. 143:1191-1191. 2013
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Selective
d -Dimer Testing for Diagnosis of a First Suspected Episode of Deep Venous Thrombosis. ACP journal club. 158:93-93. 2013 - Treatment and Prevention of Heparin-Induced Thrombocytopenia. Chest. 141:e495S-e530S. 2012
- Heparin-Induced Thrombocytopenia: Real-World Issues. Seminars in Vascular Medicine. 37:653-663. 2011
- Intracranial and fatal bleeding according to indication for long‐term oral anticoagulant therapy. Journal of Thrombosis and Haemostasis. 8:2201-2207. 2010
- Non‐necrotizing heparin‐induced skin lesions and the 4T’s score. Journal of Thrombosis and Haemostasis. 8:1483-1485. 2010
- New and Emerging Anticoagulant Therapies for Venous Thromboembolism. Current Treatment Options in Cardiovascular Medicine. 12:142-155. 2010
- High incidence of in-hospital pulmonary embolism following joint arthroplasty with dalteparin prophylaxis. Thrombosis and Haemostasis. 103:123-128. 2010
- New oral anticoagulants in development. Thrombosis and Haemostasis. 103:62-70. 2010
- Immunoassays are not created equal. Journal of Thrombosis and Haemostasis. 7:1256-1259. 2009
- Prevention and treatment of venous thromboembolism during pregnancy. Catheterization and Cardiovascular Interventions. 74:S22-S26. 2009
- Event adjudication and data monitoring in an intensive care unit observational study of thromboprophylaxis. Journal of Critical Care. 24:168-175. 2009
- Unanswered questions in venous thromboembolism. Thrombosis Research. 123:S2-S10. 2009
- Differences in clinical presentation of deep vein thrombosis in men and women. Journal of Thrombosis and Haemostasis. 6:1713-1719. 2008
- New Antithrombotic Drugs. Chest. 133:234S-256S. 2008
- The Approach to Heparin-Induced Thrombocytopenia. Seminars in Respiratory and Critical Care Medicine. 29:066-074. 2008
- Management of venous thromboembolism in patients with cancer: role of dalteparin. Vascular Health and Risk Management. Volume 4:279-287. 2008
- Beyond heparin and warfarin: the new generation of anticoagulants. Expert Opinion on Investigational Drugs. 16:271-282. 2007
- OASIS-6: should patients with acute ST-segment elevation myocardial infarction be treated with fondaparinux?. Nature Reviews Cardiology. 3:478-479. 2006
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An Evaluation of
d -Dimer in the Diagnosis of Pulmonary Embolism. ACP journal club. 144:812-812. 2006 - Changing Paradigms in the Management of Venous Thromboembolism. The American heart hospital journal. 4:135-141. 2006
- Emerging anticoagulants for the treatment of venous thromboembolism. Thrombosis and Haemostasis. 96:274-284. 2006
- Interobserver agreement on ultrasound measurements of residual vein diameter, thrombus echogenicity and Doppler venous flow in patients with previous venous thrombosis. Thrombosis Research. 117:241-247. 2006
- Pharmacology and Clinical Potential of Direct Thrombin Inhibitors. Current Pharmaceutical Design. 11:3877-3884. 2005
- New Anticoagulant Therapy. Annual Review of Medicine. 56:63-77. 2005
- Change in Thrombus Length on Venous Ultrasound and Recurrent Deep Vein Thrombosis. JAMA Internal Medicine. 164:1793-1793. 2004
- New Anticoagulant Drugs. Chest. 126:265S-286S. 2004
- New Anticoagulants for Treatment of Venous Thromboembolism. Circulation. 110:I19-I26. 2004
- Use of different d‐dimer levels to exclude venous thromboembolism depending on clinical pretest probability. Journal of Thrombosis and Haemostasis. 2:1256-1260. 2004
- Major bleeding risk with warfarin for deep vein thrombosis.. Cleveland Clinic Journal of Medicine. 71:282-282. 2004
- Clinical Impact of Bleeding in Patients Taking Oral Anticoagulant Therapy for Venous Thromboembolism. ACP journal club. 139:893-893. 2003
- An Update on New Anticoagulants. Cardiovascular and Hematological Disorders - Drug Targets. 3:287-300. 2003
- Reduction of Out-of-Hospital Symptomatic Venous Thromboembolism by Extended Thromboprophylaxis With Low-Molecular-Weight Heparin Following Elective Hip Arthroplasty. JAMA Internal Medicine. 163:1362-1362. 2003
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A Diagnostic Strategy Involving a Quantitative Latex
d -Dimer Assay Reliably Excludes Deep Venous Thrombosis. ACP journal club. 138:787-787. 2003 - Fetal-Maternal Hemorrhage Detection in Ontario. American Journal of Clinical Pathology. 119:72-77. 2003
- Fetal-maternal hemorrhage detection in Ontario. American Journal of Clinical Pathology. 119:72-77. 2003
- New Anticoagulants. Seminars in Vascular Medicine. 29:619-632. 2003
- In vitro comparison of the effect of heparin, enoxaparin and fondaparinux on tests of coagulation. Thrombosis Research. 107:241-244. 2002
- Direct thrombin inhibitors. Thrombosis Research. 106:V275-V284. 2002
- Direct Thrombin Inhibitors in Acute Coronary Syndromes. Circulation. 105:1004-1011. 2002
- New Anticoagulant Drugs. Chest. 119:95S-107S. 2001
- New anticoagulant drugs.. Journal of Thrombosis and Thrombolysis. 12:7-17. 2001
- Beyond Heparin and Aspirin. JAMA Internal Medicine. 160:749-749. 2000
- Vasoflux, a New Anticoagulant With a Novel Mechanism of Action. Circulation. 99:682-689. 1999
- Mechanism of Action of Plasminogen Activators. Thrombosis and Haemostasis. 82:974-982. 1999