Journal article
D-dimer testing to select patients with a first unprovoked venous thromboembolism who can stop anticoagulant therapy: a cohort study.
Abstract
BACKGROUND: Normal D-dimer levels after withdrawal of anticoagulant therapy are associated with a reduced risk for recurrence in patients with unprovoked venous thromboembolism (VTE) and may justify stopping treatment.
OBJECTIVE: To determine whether patients with a first unprovoked VTE and negative D-dimer test result who stop anticoagulant therapy have a low risk for recurrence.
Authors
Kearon C; Spencer FA; O'Keeffe D; Parpia S; Schulman S; Baglin T; Stevens SM; Kaatz S; Bauer KA; Douketis JD
Journal
Annals of Internal Medicine, Vol. 162, No. 1, pp. 27–34
Publisher
American College of Physicians
Publication Date
January 6, 2015
DOI
10.7326/m14-1275
ISSN
1056-8751
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AdultAnticoagulantsCause of DeathFemaleFibrin Fibrinogen Degradation ProductsHemorrhageHumansHydroxymethylglutaryl-CoA Reductase InhibitorsMaleMiddle AgedNeoplasmsPlatelet Aggregation InhibitorsProspective StudiesPulmonary EmbolismRecurrenceRisk FactorsSex FactorsStockings, CompressionVenous ThromboembolismWithholding Treatment