Intensive Care Medicine - McMaster Experts

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FACTORS ASSOCIATED WITH RESTRAINT USE IN THE SLEAP TRIAL: A MULTICENTER RANDOMIZED TRIAL COMPARING PROTOCOLIZED SEDATION WITH DAILY SEDATION INTERRUPTION VERSUS PROTOCOLIZED SEDATION ALONE IN MECHANICALLY VENTILATED ADULTS 2014
POST-INTUBATION HEMODYNAMIC INSTABILITY IN CRITICALLY ILL INTENSIVE CARE UNIT PATIENTS: A MULTICENTER STUDY 2014
VARIABILITY IN TIME TO LOCAL REGULATORY APPROVALS FOR MULTICENTER CLINICAL TRIALS - EXPERIENCES IN THE OSCILLATE TRIAL 2014
VARIATION IN NEUROMUSCULAR BLOCKER USE IN A RANDOMIZED CONTROLLED TRIAL OF HIGH-FREQUENCY OSCILLATION 2014
CASPASE-8 TYROSINE PHOSPHORYLATION IS A POTENTIAL MECHANISM OF INCREASED NEUTROPHIL SURVIVAL IN SEPTIC PATIENTS 2013
CRITICAL CARE IN SOUTHWEST UGANDA 2013
LONG-TERM PATIENT OUTCOMES AFTER PROLONGED MECHANICAL VENTILATION: THE TOWARDS RECOVER STUDY 2013
PRACTICE CHANGES IN ARDS OBSERVATIONS FROM THE OSCILLATE TRIAL 2013
RECALL OF ICU STAY IN MECHANICALLY VENTILATED PATIENTS MANAGED WITH A SEDATION PROTOCOL OR A SEDATION PROTOCOL WITH DAILY INTERRUPTION: RESULTS OF THE SLEAP MULTICENTER RANDOMIZED TRIAL 2013
ADJUNCTIVE CLONIDINE IN THE SEDATION OF MECHANICALLY VENTILATED CHILDREN: A PILOT RANDOMIZED TRIAL 2013
PILOT RANDOMIZED CONTROLLED TRIALS IN PEDIATRIC CRITICAL CARE: A SYSTEMATIC REVIEW 2013
VOLUNTARY TOXOPLASMOSIS SCREENING IN PREGNANCY UNDERESTIMATES ACTIVE INFECTION IN DEPENDENCY OF SOCIOECONOMIC FACTORS: POPULATION-BASED SURVEY OF NEONATES IN POMERANIA (SNIP) 2013
A SYSTEMATIC REVIEW OF PHARMACOTHERAPIES FOR ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) 2012
DELIRIUM SUB-SYNDROMAL DELIRIUM ANTIPSYCHOTIC USE, AND ASSOCIATED CLINICAL OUTCOMES IN CRITICALLY ILL MECHANICALLY VENTILATED PATIENTS ENROLLED IN THE SLEAP MULTICENTER RANDOMIZED TRIAL 2012
INFECTIONS IN MECHANICALLY VENTILATED PATIENTS IN CANADIAN INTENSIVE CARE UNITS 2012
PERIOPERATIVE COAGULATION PROFILE EVALUATED WITH TEG (R) PATIENTS UNDERGOING CRANIOTOMY FOR PRIMARY BRAIN TUMOR REMOVAL 2012
PHYSIOTHERAPY RESOURCE NEEDS OF SEVERE RESPIRATORY FAILURE PATIENTS 2012
RESPIRATORY PARAMETERS IMPROVES DURING DIAPHRAGMATIC PACING IN HIGH SPINAL CORD LESIONS PATIENTS 2012
A FUNCTIONAL GENOMICS APPROACH TO THE IDENTIFICATION OF BR :MARKERS OF SURVIVAL IN SEVERE SEPSIS DUE TO COMMUNITY ACQUIRED PNEUMONIA 2011
GLOBAL GENE EXPRESSION PROFILING REVEALS KEY PATHWAYS ASSOCIATED WITH THE HOST RESPONSE TO CARDIAC SURGERY AND CARDIOPULMONARY BYPASS 2011
NATIONAL SURVEY OF CRITICAL CARE NURSES' PAIN ASSESSMENT AND MANAGEMENT PRACTICES 2011
PROSPECTIVE COMPARISON OF BROAD-RANGE PCR ASSAY AND MICROBIOLOGICAL CULTURE TECHNIQUE FOR IDENTIFICATION OF PATHOGENS IN PATIENTS WITH SUSPECTED SEPSIS 2011
BLINDING ALBUMIN AND NORMAL SALINE FOR THE PRECISE PILOT MULTI-CENTRE FLUID RESUSCITATION TRIAL: A DESCRIPTION OF THE PROCEDURE 2010
AGREEMENT IN ECG INTERPRETATION IN PATIENTS WITH SEPTIC SHOCK 2009
COMPARISON OF VASOPRESSIN- VERSUS NOREPINEPHRINE-ASSOCIATED ISCHEMIC ECG CHANGES IN SEPTIC SHOCK 2009
IMPROVING QUALITY, SAFETY AND COSTS BY IMPLEMENTING A PERFORMANCE MEASUREMENT AND MANAGEMENT APPROACH FOR COMMON INVESTIGATIONS IN THE ICU 2009
SURVEY OF PAIN ASSESSMENT PRACTICES FOR CRITICALLY-ILL PATIENTS UNABLE TO SELF-REPORT PAIN 2009
Enteral sedation in the critical patient 2003
Intraoperative factors associated with ICU complications after intrarenal aortic reconstruction 2003
Non-invasive mask ventilation in the emergency treatment of acute cardiogenic pulmonary edema 2002
Correction: Conservative or liberal oxygen targets in patients on venoarterial extracorporeal membrane oxygenation.. 50:2241-2242. 2024
Preventing stress ulcer bleeding.. 50:2162-2165. 2024
The choice of resuscitation fluids-Ionic composition matters. Author's reply.. 50:2194. 2024
Critical illness and the gut microbiome. 50:1692-1694. 2024
Conservative or liberal oxygen targets in patients on venoarterial extracorporeal membrane oxygenation.. 50:1470-1483. 2024
Comparison of venovenous extracorporeal membrane oxygenation, prone position and supine mechanical ventilation for severely hypoxemic acute respiratory distress syndrome: a network meta-analysis. 50:1021-1034. 2024
Frailty is crucial in FORECASTing outcomes in critical care. 50:1119-1122. 2024
Frailty, Outcomes, Recovery and Care Steps of Critically Ill Patients (FORECAST): a prospective, multi-centre, cohort study. 50:1064-1074. 2024
European Society of Intensive Care Medicine clinical practice guideline on fluid therapy in adult critically ill patients. Part 1: the choice of resuscitation fluids. 50:813-831. 2024
Mind the gap: understanding the discordance between the ATS and ESICM ARDS guidelines—the ATS perspective. 50:937-940. 2024
Mechanical circulatory support for cardiogenic shock: a network meta-analysis of randomized controlled trials and propensity score-matched studies. 50:209-221. 2024
Initiation of continuous renal replacement therapy versus intermittent hemodialysis in critically ill patients with severe acute kidney injury: a secondary analysis of STARRT-AKI trial. 49:1305-1316. 2023
The impact of religion on changes in end-of-life practices in European intensive care units: a comparative analysis over 16 years. 49:1339-1348. 2023
Differences in directives to limit treatment and discontinue mechanical ventilation between elderly and very elderly patients: a substudy of a multinational observational study. 49:1181-1190. 2023
To mobilise or not to mobilise: is that the right question?. 49:1000-1004. 2023
Physical rehabilitation in the intensive care unit: past, present, and future. 49:864-867. 2023
Correction: Impact of renal-replacement therapy strategies on outcomes for patients with chronic kidney disease: a secondary analysis of the STARRT-AKI trial. 49:381-383. 2023
Association between acute disease severity and one-year quality of life among post-hospitalisation COVID-19 patients: Coalition VII prospective cohort study. 49:166-177. 2023
Clustering analysis of geriatric and acute characteristics in a cohort of very old patients on admission to ICU. 48:1726-1735. 2022
Delivering optimal renal replacement therapy to critically ill patients with acute kidney injury. 48:1368-1381. 2022
Corticosteroids for severe community-acquired pneumonia: a story without an ending. 48:1053-1055. 2022
Dexmedetomidine vs other sedatives in critically ill mechanically ventilated adults: a systematic review and meta-analysis of randomized trials. 48:811-840. 2022
Use of dexmedetomidine for sedation in mechanically ventilated adult ICU patients: a rapid practice guideline. 48:801-810. 2022
Characterizing systematic challenges in sample size determination for sepsis trials. 48:750-752. 2022
Correction to: Increased 30-day mortality in very old ICU patients with COVID-19 compared to patients with respiratory failure without COVID-19. 48:797-799. 2022
Diarrhea during critical illness: a multicenter cohort study. 48:570-579. 2022
Increased 30-day mortality in very old ICU patients with COVID-19 compared to patients with respiratory failure without COVID-19. 48:435-447. 2022
Noninvasive respiratory support following extubation in critically ill adults: a systematic review and network meta-analysis. 48:137-147. 2022
Transfusion strategies in bleeding critically ill adults: a clinical practice guideline from the European Society of Intensive Care Medicine. 47:1368-1392. 2021
Targeted temperature management following out-of-hospital cardiac arrest: a systematic review and network meta-analysis of temperature targets. 47:1078-1088. 2021
Corticosteroids in COVID-19 and non-COVID-19 ARDS: a systematic review and meta-analysis. 47:521-537. 2021
Twenty articles that critical care clinicians should read about COVID-19. 47:337-341. 2021
Treating critically ill anemic patients with erythropoietin: less is more. 47:256-257. 2021
Efficacy and safety of tranexamic acid in acute traumatic brain injury: a systematic review and meta-analysis of randomized-controlled trials. 47:14-27. 2021
Analgesia and sedation in patients with ARDS. 46:2342-2356. 2020
Pharmacological principles guiding prolonged glucocorticoid treatment in ARDS. 46:2284-2296. 2020
The role for high flow nasal cannula as a respiratory support strategy in adults: a clinical practice guideline. 46:2226-2237. 2020
Efficacy and safety of gastrointestinal bleeding prophylaxis in critically ill patients: an updated systematic review and network meta-analysis of randomized trials. 46:1987-2000. 2020
Neuromuscular blockade in patients with ARDS: a rapid practice guideline. 46:1977-1986. 2020
A way toward ventilator-associated lower respiratory tract infection research: reply. 46:1506-1507. 2020
Managing ICU surge during the COVID-19 crisis: rapid guidelines. 46:1303-1325. 2020
Diagnosis of ventilator-associated pneumonia in critically ill adult patients—a systematic review and meta-analysis. 46:1170-1179. 2020
Guidelines seek unbiased recommendations. 46:1065-1069. 2020
Transfusion strategies in non-bleeding critically ill adults: a clinical practice guideline from the European Society of Intensive Care Medicine. 46:673-696. 2020
Executive summary: surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children. 46:1-9. 2020
Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children. 21:e52-e106. 2020
Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children. 46:10-67. 2020
Extracorporeal liver support in patients with liver failure: a systematic review and meta-analysis of randomized trials. 46:1-16. 2020
The contribution of frailty, cognition, activity of daily life and comorbidities on outcome in acutely admitted patients over 80 years in European ICUs: the VIP2 study. 46:57-69. 2020
Frailty and invasive mechanical ventilation: association with outcomes, extubation failure, and tracheostomy. 45:1742-1752. 2019
Intensive care medicine rapid practice guidelines (ICM-RPG): paving the road of the future. 45:1639-1641. 2019
Mortality and costs following extracorporeal membrane oxygenation in critically ill adults: a population-based cohort study. 45:1580-1589. 2019
Predictors of gastrointestinal bleeding in adult ICU patients: a systematic review and meta-analysis. 45:1347-1359. 2019
High-flow nasal cannula compared with conventional oxygen therapy for acute hypoxemic respiratory failure: author's reply. 45:1171-1171. 2019
New-onset atrial fibrillation in adult critically ill patients: a scoping review. 45:928-938. 2019
High flow nasal cannula compared with conventional oxygen therapy for acute hypoxemic respiratory failure: a systematic review and meta-analysis. 45:563-572. 2019
A multicentre controlled pre–post trial of an implementation science intervention to improve venous thromboembolism prophylaxis in critically ill patients. 45:211-222. 2019
Conflicts of interest disclosure forms and management in critical care clinical practice guidelines. 44:1691-1698. 2018
Understanding conflicts of interest. 44:1738-1740. 2018
Correction to: Withholding or withdrawing of life-sustaining therapy in older adults (≥ 80 years) admitted to the intensive care unit. 44:1598-1601. 2018
More than the tip of the iceberg: association between disabilities and inability to attend a clinic-based post-ICU follow-up and how it may impact on health inequalities. 44:1352-1354. 2018
Withholding or withdrawing of life-sustaining therapy in older adults (≥ 80 years) admitted to the intensive care unit. 44:1027-1038. 2018
Are systematic reviews and meta-analyses still useful research? Yes. 44:512-514. 2018
Guidelines for the diagnosis and management of critical illness-related corticosteroid insufficiency (CIRCI) in critically ill patients (Part II): Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM) 2017. 44:474-477. 2018
Prevalence and predictors of severe grief reactions and desire for support following a death in the intensive care unit: a multicentre observational study. 44:521-522. 2018
Target blood pressure for septic and vasodilatory shock: what is optimal?. 44:548-549. 2018
Correction to: Guidelines for the diagnosis and management of critical illness-related corticosteroid insufficiency (CIRCI) in critically ill patients (Part I): Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM) 2017. 44:401-402. 2018
Correction to: Efficacy and safety of stress ulcer prophylaxis in critically ill patients: a network meta-analysis of randomized trials. 44:277-278. 2018
Conflicts of interest disclosure forms and management in critical care clinical practice guidelines. 1-8. 2018
Efficacy and safety of stress ulcer prophylaxis in critically ill patients: a network meta-analysis of randomized trials. 44:1-11. 2018
Financial conflicts of interest in clinical research. 44. 2018
Pooled analysis of higher versus lower blood pressure targets for vasopressor therapy septic and vasodilatory shock. 44:12-21. 2018
Critical illness-related corticosteroid insufficiency (CIRCI): a narrative review from a Multispecialty Task Force of the Society of Critical Care Medicine (SCCM) and the European Society of Intensive Care Medicine (ESICM). 43:1781-1792. 2017
Guidelines for the diagnosis and management of critical illness-related corticosteroid insufficiency (CIRCI) in critically ill patients (Part I): Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM) 2017. 43:1751-1763. 2017
The impact of frailty on ICU and 30-day mortality and the level of care in very elderly patients (≥ 80 years). 43:1820-1828. 2017
The ICM research agenda on intensive care unit-acquired weakness. 43:1270-1281. 2017
The intensive care delirium research agenda: a multinational, interprofessional perspective. 43:1329-1339. 2017
CCCS-SSAI WikiRecs clinical practice guideline: vasopressor blood pressure targets in critically ill adults with hypotension and vasopressor use in early traumatic shock. 43:1062-1064. 2017
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016. 43:304-377. 2017
Prolonged glucocorticoid treatment is associated with improved ARDS outcomes: analysis of individual patients’ data from four randomized trials and trial-level meta-analysis of the updated literature. 42:829-840. 2016
Higher versus lower blood pressure targets for vasopressor therapy in shock: a multicentre pilot randomized controlled trial. 42:542-550. 2016
Recovery after critical illness in patients aged 80 years or older: a multi-center prospective observational cohort study. 41:1911-1920. 2015
Fluid type and the use of renal replacement therapy in sepsis: a systematic review and network meta-analysis. 41:1561-1571. 2015
Ten things you should consider before you believe a clinical practice guideline. 41:1340-1342. 2015
Trials on stress ulcer prophylaxis: finding the balance between benefit and harm. Response to Krag et al.. 41:1369-1369. 2015
Intensive versus conventional glucose control in critically ill patients with traumatic brain injury: long-term follow-up of a subgroup of patients from the NICE-SUGAR study. 41:1037-1047. 2015
Prevalence and outcome of gastrointestinal bleeding and use of acid suppressants in acutely ill adult intensive care patients. 41:833-845. 2015
Primum non nocere and challenging conventional treatment. 41:933-935. 2015
Is there a role for physician involvement in introducing research to surrogate decision makers in the intensive care unit? (The Approach trial: a pilot mixed methods study). 41:58-67. 2015
Consensus on circulatory shock and hemodynamic monitoring. Task force of the European Society of Intensive Care Medicine. 40:1795-1815. 2014
Clinical meaning of the GRADE rules. 40:877-879. 2014
Sepsis and the innate-like response. 40:249-251. 2014
Physicians declining patient enrollment in a critical care trial: a case study in thromboprophylaxis. 39:2115-2125. 2013
Risk factors and impact of major bleeding in critically ill patients receiving heparin thromboprophylaxis. 39:2135-2143. 2013
Intra-abdominal hypertension and the abdominal compartment syndrome: updated consensus definitions and clinical practice guidelines from the World Society of the Abdominal Compartment Syndrome. 39:1190-1206. 2013
Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock, 2012. 39:165-228. 2013
Surrogate decision makers’ attitudes towards research decision making for critically ill patients. 38:1616-1623. 2012
Consensus statement of the ESICM task force on colloid volume therapy in critically ill patients: authors’ reply to comments by Zacharowski et al.. 38:1558-1559. 2012
Unless high-quality clinical data show they are safe, synthetic colloids should not be used in patients with head injury. 38:1563-1564. 2012
Safety of gelatin for volume resuscitation—a systematic review and meta-analysis. 38:1134-1142. 2012
Consensus statement of the ESICM task force on colloid volume therapy in critically ill patients. 38:368-383. 2012
Factors affecting consent in pediatric critical care research. 38:153-159. 2012
Impaired microvascular perfusion in sepsis requires activated coagulation and P-selectin-mediated platelet adhesion in capillaries. 36:1928-1934. 2010
The effects of vasopressin on acute kidney injury in septic shock. 36:83-91. 2010
Patients’ preferences for enrolment into critical-care trials. 35:1703-1712. 2009
The ‘Consent to Research’ paradigm in critical care: challenges and potential solutions. 35:1655-1658. 2009
Construction of the Sophia Observation withdrawal Symptoms-scale (SOS) for critically ill children. 35:1075-1081. 2009
Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008. 34:1163-1164. 2008
Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008. 34:783-785. 2008
Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008. 34:17-60. 2008
Antibiotic management of suspected nosocomial ICU-acquired infection: Does prolonged empiric therapy improve outcome?. 33:1369-1378. 2007
Novel indications for the Boussignac CPAP valve. 33:374-375. 2007
William John Sibbald: in memoriam. 32:1945-1946. 2006
Levosimendan in septic cardiac failure. 31:164-165. 2005
Neither baseline tests of molecular hypercoagulability nor D-dimer levels predict deep venous thrombosis in critically ill medical-surgical patients. 31:48-55. 2005
Clinician discomfort with life support plans for mechanically ventilated patients. 30:1783-1790. 2004
Screening of ARDS patients using standardized ventilator settings: influence on enrollment in a clinical trial. 30:1111-1116. 2004
Glycemic control in the ICU: a multicenter survey. 30:798-803. 2004
Outcome of older patients receiving mechanical ventilation. 30:639-646. 2004
Effects of C1 esterase inhibitor administration on intestinal functional capillary density, leukocyte adherence and mesenteric plasma extravasation during experimental endotoxemia. 30:309-314. 2004
A readers' guide to the interpretation of diagnostic test properties: clinical example of sepsis. 29:1043-1051. 2003
2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. 29:530-538. 2003
Response to Bendjelid, "Impact of pulmonary artery occlusion pressure value on the definition of acute respiratory distress syndrome". 29:500-500. 2003
Decision-making in the ICU: perspectives of the substitute decision-maker. 29:75-82. 2003
High values of the pulmonary artery wedge pressure in patients with acute lung injury and acute respiratory distress syndrome. 28:1073-1077. 2002
Influences on physicians' choices of intravenous colloids. 28:917-924. 2002
Physicians' attitude to use heat and moisture exchangers or heated humidifiers: a Franco-Canadian survey. 28:719-725. 2002
Clinical estimation of trunk position among mechanically ventilated patients. 28:304-309. 2002
Withdrawing and withholding life support in the intensive care unit: a Spanish prospective multi-centre observational study. 27:1744-1749. 2001
Pulmonary oxygen consumption: a hypothesis to explain the increase in oxygen consumption of low birth weight infants with lung disease. 27:1636-1642. 2001
A multicenter, open-label, prospective, randomized, dose-ranging pharmacokinetic study of the anti-TNF-α antibody afelimomab in patients with sepsis syndrome. 27:1169-1178. 2001
Doctors' perceptions of the effects of interventions tested in prospective, randomised, controlled, clinical trials: results of a survey of ICU physicians. 27:548-554. 2001
Recent evidence for intravenous fluid choice in patients with severe infection. 27:609-612. 2001
On the need for observational studies to design and interpret randomized trials in ICU patients: a case study in stress ulcer prophylaxis. 27:347-354. 2001
Lung-protective mechanical ventilation strategies in ARDS. 26:1151-1155. 2000
Anti-microbial or antiseptic impregnated central venous catheters: update on a "central" debate. 26:246-249. 2000
Using and understanding sedation scoring systems: a systematic review. 26:275-285. 2000
Ventilator associated pneumonia: perspectives on the burden of illness. 26:S031-S037. 2000
ARDS in patients with thermal injury. 25:1231-1236. 1999
Concerning “Human albumin administration in critically ill patients”. 25:1033-1033. 1999
Reply. 25:1033-1033. 1999
Neuromuscular disorders acquired in the ICU. 25:641-641. 1999
Reply. 25:642-642. 1999
Human albumin administration in critically ill patients. 25:323-325. 1999
Acquired neuromuscular disorders in critically ill patients: a systematic review. 24:1242-1250. 1998
Impaired gastric emptying in mechanically ventilated, critically ill patients. 22:1339-1344. 1996
Poster Discussions. 22:S306-S306. 1996
Practice guidelines — an emerging synthetic science. 20:540-541. 1994
Inhaled nitric oxide in acute respiratory failure: Dose-response curves. 20:319-327. 1994
Predicting outcome in ICU patients. 20:390-397. 1994
Enteral nutrition in the critically ill patient: A critical review of the evidence. 19:435-442. 1993
Organization and management I. 18:S70-S71. 1992

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