Journal article
Sepsis subtypes and differential treatment response to vitamin C: biological sub-study of the LOVIT trial
Abstract
PurposeWe hypothesised that the biological heterogeneity of sepsis may highlight sepsis subtypes with differences in response to intravenous vitamin C treatment in the Lessening Organ Dysfunction with VITamin C (LOVIT) trial. Our aims were to identify sepsis subtypes and to test whether sepsis subtypes have differences in treatment effect to vitamin C and describe putative biological effects of vitamin C treatment.MethodsWe measured biomarkers …
Authors
Rynne J; Mosavie M; Masse M-H; Ménard J; Battista M-C; Maslove DM; del Sorbo L; St-Arnaud C; DAragon F; Fox-Robichaud A
Journal
Intensive Care Medicine, Vol. 51, No. 1, pp. 82–93
Publisher
Springer Nature
Publication Date
1 2025
DOI
10.1007/s00134-024-07733-9
ISSN
0342-4642