selected scholarly activity
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academic article
- Effects of Two Distinct Psychoactive Microbes, Lacticaseibacillus rhamnosus JB-1 and Limosilactobacillus reuteri 6475, on Circulating and Hippocampal mRNA in Male Mice. International Journal of Molecular Sciences. 23:9653-9653. 2022
- Regulatory T Cell Modulation by Lactobacillus rhamnosus Improves Feather Damage in Chickens. Frontiers in Veterinary Science. 9:855261. 2022
- Severe, but not moderate asthmatics share blood transcriptomic changes with post-traumatic stress disorder and depression. PLoS ONE. 17:e0275864-e0275864. 2022
- Differential effects of chronic immunosuppression on behavioral, epigenetic, and Alzheimer’s disease-associated markers in 3xTg-AD mice. Alzheimer's Research and Therapy. 13:30. 2021
- Identification of SSRI-evoked antidepressant sensory signals by decoding vagus nerve activity. Scientific Reports. 11:21130. 2021
- L. rhamnosus improves the immune response and tryptophan catabolism in laying hen pullets. Scientific Reports. 11:19538. 2021
- Limosilactobacillus reuteri DSM‐17938 for preventing cough in adults with mild allergic asthma: A double‐blind randomized placebo‐controlled cross‐over study. Clinical and Experimental Allergy. 51:1133-1143. 2021
- Loss of vagal integrity disrupts immune components of the microbiota-gut-brain axis and inhibits the effect of Lactobacillus rhamnosus on behavior and the corticosterone stress response. Neuropharmacology. 195:108682-108682. 2021
- Ingestion of Lactobacillus rhamnosus modulates chronic stress-induced feather pecking in chickens. Scientific Reports. 11:17119. 2021
- Vagotomy and insights into the microbiota-gut-brain axis. Neuroscience Research. 168:20-27. 2021
- A Budding Relationship: Bacterial Extracellular Vesicles in the Microbiota-Gut-Brain Axis. International Journal of Molecular Sciences. 21:8899-8899. 2020
- Publisher Correction: Increased persistence of avoidance behaviour and social deficits with L.rhamnosus JB-1 or selective serotonin reuptake inhibitor treatment following social defeat. Scientific Reports. 10:18501. 2020
- Publisher Correction: Sex dependent effects of post-natal penicillin on brain, behavior and immune regulation are prevented by concurrent probiotic treatment. Scientific Reports. 10:18355. 2020
- Increased persistence of avoidance behaviour and social deficits with L.rhamnosus JB-1 or selective serotonin reuptake inhibitor treatment following social defeat. Scientific Reports. 10:13485. 2020
- CD4+CD25+ T Cells are Essential for Behavioral Effects of Lactobacillus rhamnosus JB-1 in Male BALB/c mice. Brain, Behavior, and Immunity. 88:451-460. 2020
- Cecal motility and the impact of Lactobacillus in feather pecking laying hens. Scientific Reports. 10:12978. 2020
- Sex dependent effects of post-natal penicillin on brain, behavior and immune regulation are prevented by concurrent probiotic treatment. Scientific Reports. 10:10318. 2020
- The vagus nerve is necessary for the rapid and widespread neuronal activation in the brain following oral administration of psychoactive bacteria. Neuropharmacology. 170:108067-108067. 2020
- Oral selective serotonin reuptake inhibitors activate vagus nerve dependent gut-brain signalling. Scientific Reports. 9:14290. 2019
- Immune to fear: With a little help from old friends. Brain, Behavior, and Immunity. 79:8-9. 2019
- Antibiotics and the nervous system: More than just the microbes?. Brain, Behavior, and Immunity. 77:7-15. 2019
- Effects of Acute Tryptophan Depletion on Repetitive Behavior in Laying Hens. Frontiers in Veterinary Science. 6:230. 2019
- Mast Cells in Neuroimmune Interactions. Trends in Neurosciences. 42:43-55. 2019
- The Role of Tryptophan-Kynurenine in Feather Pecking in Domestic Chicken Lines. Frontiers in Veterinary Science. 6:209. 2019
- Differences in cecal microbiome of selected high and low feather-pecking laying hens. Poultry Science. 97:3009-3014. 2018
- Antibiotics in early life: dysbiosis and the damage done. FEMS Microbiology Reviews. 42:489-499. 2018
- Sex-Dependent Differences in Spontaneous Autoimmunity in Adult 3xTg-AD Mice. Journal of Alzheimer's Disease. 63:1191-1205. 2018
- Human Milk Oligosaccharides Attenuate Antigen-Antibody Complex Induced Chemokine Release from Human Intestinal Epithelial Cell Lines. Journal of Food Science. 83:499-508. 2018
- The vagus nerve modulates BDNF expression and neurogenesis in the hippocampus. European Neuropsychopharmacology. 28:307-316. 2018
- Oral treatment with Lactobacillus rhamnosus attenuates behavioural deficits and immune changes in chronic social stress. BMC Medicine. 15:7. 2017
- The bacterial quorum-sensing molecule, N-3-oxo-dodecanoyl-l-homoserine lactone, inhibits mediator release and chemotaxis of murine mast cells. Inflammation Research. 66:259-268. 2017
- Antibiotic Driven Changes in Gut Motility Suggest Direct Modulation of Enteric Nervous System. Frontiers in Neuroscience. 11:588. 2017
- Moody microbes or fecal phrenology: what do we know about the microbiota-gut-brain axis?. BMC Medicine. 14:58. 2016
- Microbes taming mast cells: Implications for allergic inflammation and beyond. Behavioural Processes European Journal of Pharmacology European Journal of Pharmacology - Molecular Pharmacology Section. 778:169-175. 2016
- Posttraumatic Stress Disorder: Does the Gut Microbiome Hold the Key?. Canadian Journal of Psychiatry. 61:204-213. 2016
- Structural & functional consequences of chronic psychosocial stress on the microbiome & host. Psychoneuroendocrinology. 63:217-227. 2016
- The Parasympathetic Nervous System as a Regulator of Mast Cell Function. Methods in Molecular Biology. 1220:141-154. 2015
- Nutraceutical Regulation of the Neuroimmunoendocrine Super-system. AAPS Advances in the Pharmaceutical Sciences Series. 12:415-437. 2014
- Probiotics and Lung Immune Responses. Proceedings of the American Thoracic Society. 11:S33-S37. 2014
- Six tips for a successful dermatology visit. In Practice. 35:7-11. 2013
- Gut microbes as modulators of the neuro-immuno-endocrine system. PharmaNutrition. 1:115-122. 2013
- Lactobacillus rhamnosus Ingestion Promotes Innate Host Defense in an Enteric Parasitic Infection. Clinical and Diagnostic Laboratory Immunology Clinical and Vaccine Immunology. 20:818-826. 2013
- Fucosylated but Not Sialylated Milk Oligosaccharides Diminish Colon Motor Contractions. PLoS ONE. 8:e76236-e76236. 2013
- Natural Killer Cells in Asthma. Frontiers in Immunology. 4:159. 2013
- Voices from within: gut microbes and the CNS. Cellular and Molecular Life Sciences. 70:55-69. 2013
- Communication between gastrointestinal bacteria and the nervous system. Current Opinion in Pharmacology. 12:667-672. 2012
- On communication between gut microbes and the brain. Current Opinion in Gastroenterology. 28:557-562. 2012
- The Nervous System as a Critical Regulator of Immune Responses Underlying Allergy. Current Pharmaceutical Design. 18:2290-2304. 2012
- Reply to McLean et al. and Burnet: The microbiome–gut–brain axis as a pathway toward next generation psychotropics. Proceedings of the National Academy of Sciences of the United States of America. 109:E176-E176. 2012
- A Lactobacillus rhamnosus Strain Induces a Heme Oxygenase Dependent Increase in Foxp3+ Regulatory T Cells. PLoS ONE. 7:e47556-e47556. 2012
- Systemic Effects of Ingested Lactobacillus Rhamnosus: Inhibition of Mast Cell Membrane Potassium (IKCa) Current and Degranulation. PLoS ONE. 7:e41234-e41234. 2012
- The Mast Cell-Nerve Functional Unit: A Key Component of Physiologic and Pathophysiologic Responses. Progress in Allergy Chemical Immunology Chemical Immunology and Allergy. 98:196-221. 2012
- Mucosal exposure to cockroach extract induces allergic sensitization and allergic airway inflammation. Canadian Journal of Allergy and Clinical Immunology Allergy, Asthma and Clinical Immunology. 7:22. 2011
- Probiotics in United Airways Disease: Response. Chest. 140:1100-1101. 2011
- Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve. Proceedings of the National Academy of Sciences of the United States of America. 108:16050-16055. 2011
- Live Lactobacillus rhamnosus Is Essential for the Inhibitory Effect on Tumor Necrosis Factor Alpha-Induced Interleukin-8 Expression. Infection and Immunity. 79:2961-2961. 2011
- Probiotics and Lung Diseases. Chest. 139:901-908. 2011
- The vagus nerve modulates CD4+ T cell activity. Brain, Behavior, and Immunity. 24:316-323. 2010
- Bacterial strain-specific induction of Foxp3+T regulatory cells is protective in murine allergy models. Clinical and Experimental Allergy. 40:811-819. 2010
- Immunomodulation by Commensal and Probiotic Bacteria. Immunological Investigations Immunological Communications. 39:429-448. 2010
- Mood and gut feelings. Brain, Behavior, and Immunity. 24:9-16. 2010
- Lactobacillus reuteri enhances excitability of colonic AH neurons by inhibiting calcium‐dependent potassium channel opening. Journal of Cellular and Molecular Medicine. 13:2261-2270. 2009
- Lactobacillus reuteri–induced Regulatory T cells Protect against an Allergic Airway Response in Mice. American Journal of Respiratory and Critical Care Medicine. 179:186-193. 2009
- Should we Target Allergen Protease Activity to Decrease the Burden of Allergic Airway Inflammation?. Current Drug Targets: Inflammation and Allergy Inflammation and Allergy - Drug Targets. 7:288-295. 2008
- Oral Treatment with Live Lactobacillus reuteri Inhibits the Allergic Airway Response in Mice. American Journal of Respiratory and Critical Care Medicine. 175:561-569. 2007
- Inhibitory effects of Lactobacillus reuteri on visceral pain induced by colorectal distension in Sprague-Dawley rats. Gut. 55:191-196. 2006
- Proteinase-activated receptor 2 activation in the airways enhances antigen-mediated airway inflammation and airway hyperresponsiveness through different pathways. Journal of Allergy and Clinical Immunology. 115:623-630. 2005
- Live Lactobacillus reuteri Is Essential for the Inhibitory Effect on Tumor Necrosis Factor Alpha-Induced Interleukin-8 Expression. Infection and Immunity. 72:5308-5314. 2004
- Opposing Effects of Short- and Long-term Stress on Airway Inflammation. American Journal of Respiratory and Critical Care Medicine. 169:220-226. 2004
- Commentary 10. Experimental Dermatology. 12:906-907. 2003
- What is the physiological function of mast cells?. Experimental Dermatology. 12:886-886. 2003
- CCR3. American Journal of Respiratory Cell and Molecular Biology. 28:405-409. 2003
- Inhibition of Calpain Is a Component of Nitric Oxide-Induced Down-Regulation of Human Mast Cell Adhesion. Journal of Immunology. 170:287-293. 2003
- Mast cells and nitric oxide: control of production, mechanisms of response. International Immunopharmacology. 1:1525-1541. 2001
- Immunomodulation by the submandibular gland. NeuroImmune Biology. 1:203-224. 2001
- Opinion and Reality: Bridging the Gap. Canadian Journal of Psychiatry. 45:885-889. 2000
- Clinical consequences of mast cell heterogeneity. Inflammation Research. 49:147-154. 2000
- Sensory neuropeptides induce histamine release from bronchoalveolar lavage cells in both nonasthmatic coughers and cough variant asthmatics. Clinical and Experimental Allergy. 30:225-232. 2000
- Nasal provocation with AMP. Thorax. 54:1050-1050. 1999
- Adenosine, mast cells and asthma. Inflammation Research. 48:301-307. 1999
- Adenosine induces histamine release from human bronchoalveolar lavage mast cells. Clinical Science. 96:349-349. 1999
- Bronchoalveolar lavage findings in patients with chronic nonproductive cough. European Respiratory Journal European Respiratory Journal, Supplement. 13:66-70. 1999
- Pharmacological regulation of mediator release from human mast cells. Clinical and Experimental Allergy. 28:1171-1173. 1998
- The modulatory effects of WE-14 on histamine release from rat peritoneal mast cells.. Inflammation Research. 46 Suppl 1:S13-S14. 1997
- Airways inflammation in chronic non-productive cough. Thorax. 51. 1996
- Increased MCP-1, RANTES, and MIP-1 alpha in bronchoalveolar lavage fluid of allergic asthmatic patients. American Journal of Respiratory and Critical Care Medicine. 153:1398-1404. 1996
- Increased MCP-1, RANTES, and MIP-1alpha in bronchoalveolar lavage fluid of allergic asthmatic patients.. American Journal of Respiratory and Critical Care Medicine. 153:1398-1404. 1996
- Monocyte chemotactic protein-2, monocyte chemotactic protein-3, and fibroblast-induced cytokine. Three new chemokines induce chemotaxis and activation of basophils.. Journal of Immunology. 153:3155-3159. 1994
- RANTES is a chemotactic and activating factor for human eosinophils.. Journal of Immunology. 150:3442-3448. 1993
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chapter
- The gut microbiota and the CNS. 409-430. 2016
- Vagal Pathways for Microbiome-Brain-Gut Axis Communication. Advances in Experimental Medicine and Biology. 115-133. 2014
- Submandibular gland factors and neuroendocrine regulation of inflammation and immunity. 169-195. 2013
- Autonomic Neuroimmunology. 1003-1008. 2009
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conference paper
- Early pathologies in the 3XTG-ad mouse model of Alzheimer's disease. Journal of Neurochemistry. 180-180. 2019
- Mechanical stress-induced mast cell degranulation activates TGF-β1 signalling pathway in pulmonary fibrosis. Thorax. 455-465. 2019
- S20. Depletion of CD4+CD25+ Regulatory T Cells Inhibits the Anxiolytic Effects of Lactobacillus Rhamnosus (JB-1). Biological Psychiatry. S304-S304. 2019
- Sex-dependent effects of postnatal exposure to low dose penicillin on the microbiota-gut-brain axis. Neurogastroenterology and Motility. 2018
- The Fibrotic Extracellular Matrix (ecm) Induces Mast Cell Degranulation And Phenotypes Changing. American Journal of Respiratory and Critical Care Medicine. 2017
- Neuroimmune aspects of food intake. International Dairy Journal. 253-258. 2010
- The sympathetic nervous system regulates the release of anti-inflammatory peptides from salivary glands. Journal of Immunology. 2009
- Foxp3+CD4+ Regulatory T cells Induced by Oral Treatment with Lactobacillus reuteri Protect Against Experimentally Induced Asthma in Mice. Journal of Allergy and Clinical Immunology. S266-S266. 2008
- Effect of lactobacillus SP (Lb) probiotic ingestion on membrane properties of intrinsic sensory neurons in rat colon. Gastroenterology. A401-A401. 2007
- The vagus nerve is involved in constitutive downregulation of acute and chronic intestinal inflammation through the alpha7 nicotinic receptor pathway. Gastroenterology. A50-A50. 2007
- Oral Treatment with Live Lactobacillus Reuteri Attenuates the Allergic Airway Response in Mice. Journal of Allergy and Clinical Immunology. S315-S315. 2006
- Production of nitric oxide by mast cells and effects on their activity. ALLERGY FRONTIERS AND FUTURES. 142-144. 2003
- Nitric oxide down-regulates human mast cell adhesion to extracellular matrix proteins. Journal of Allergy and Clinical Immunology. S273-S273. 2002
- Inhibition of human mast cell adhesion by nitric oxide. FASEB Journal. A1040-A1040. 2001
- Nitric oxide induced down-regulation of human mast cell adhesion. Journal of Allergy and Clinical Immunology. S286-S286. 2001
- Histamine release from basophils and bronchoalveolar lavage (BAL) cells induced by radiographic contrast media (RCM). American Journal of Respiratory and Critical Care Medicine. A656-A656. 1999
- Prostaglandin E-2 and F-2 alpha concentrations in bronchoalveolar lavage fluid from non-asthmatic coughers, cough variant asthmatics and healthy subjects. American Journal of Respiratory and Critical Care Medicine. A97-A97. 1999
- The modulatory effects of WE-14 on histamine release from rat peritoneal mast cells. Inflammation Research. 13-14. 1997
- The effect of adenosine on histamine release from rat peritoneal mast cells induced by the calcium ionophore in buffers containing different calcium concentrations. Inflammation Research. S19-S20. 1996
- The lung inflammatory responses to CC chemokines - MCP-1, MCP-3, MIP-1 alpha and RANTES in mice challenged in vivo.. Journal of Allergy and Clinical Immunology. 404-404. 1996
- IL-5 ACTIVATES LYN KINASE, AND PROPAGATES SIGNALS TO THE NUCLEUS VIA THE RAS-RAF-1-MEK-MAP KINASE PATHWAY IN EOSINOPHILS. Journal of Allergy and Clinical Immunology. 344-344. 1995
- THE EFFECT OF IMMUNOTHERAPY (IT) ON MONONUCLEAR CELL (MNC) CYTOKINE PRODUCTION - HEIGHTENED SYNTHESIS OF IL-8 BUT NO CHANGE IN MCP-1, MIP-1-ALPHA OR TGF-BETA PRODUCTION. Journal of Allergy and Clinical Immunology. 316-316. 1995
- The lnterleukin-5/Receptor Interaction Activates Lyn and Jak2 Tyrosine Kinases and Propagates Signals via the Ras-Raf-1-MAP Kinase and the Jak-STAT Pathways in Eosinophils. International Archives of Allergy and Immunology. 226-227. 1995
- Partial characterisation of potentially-novel peptides from the mammalian pancreas and adrenal medulla. Regulatory Peptides. 283-283. 1994
- MONOCYTE CHEMOTACTIC PEPTIDE-3 (MCP-3), A NEW C-C CHEMOKINE, IS THE 2ND MOST POTENT HISTAMINE-RELEASING FACTOR FOR BASOPHILS. FASEB Journal. A480-A480. 1994
- ACTIVATION OF EOSINOPHILS AND PARTIALLY DIFFERENTIATED HL-60 CELLS BY IL-5 UTILIZES MAP KINASE AS AN INTERMEDIATE STEP IN SIGNAL-TRANSDUCTION. Journal of Allergy and Clinical Immunology. 267-267. 1994
- DETECTION AND QUANTITATION OF RANTES AND MIP-1 ALPHA IN BRONCHOALVEOLAR LAVAGE (BAL) FLUID AND THEIR MESSENGER-RNA IN LAVAGE CELLS. Journal of Allergy and Clinical Immunology. 183-183. 1994
- FIBROBLAST-INDUCED CYTOKINE (FIC) AND MONOCYTE CHEMOATTRACTANT PEPTIDE-2 (MCP-2), 2 NEW BETA-CHEMOKINES, CAUSE BASOPHIL HISTAMINE-RELEASE. Journal of Allergy and Clinical Immunology. 215-215. 1994
- INVOLVEMENT OF RAF-1 KINASE IN INTRACELLULAR SIGNALING OF INTERLEUKIN-5 IN EOSINOPHILS AND PARTIALLY DIFFERENTIATED HL-60 CELLS. Journal of Allergy and Clinical Immunology. 267-267. 1994
- MECHANISM OF ANTIALLERGIC ACTIVITY OF MISOPROSTOL - EFFECTS ON EOSINOPHILS AND MONONUCLEAR-CELLS INVIVO AND INVITRO. American Review of Respiratory Disease. A823-A823. 1993
- RANTES IS A CHEMOTACTIC AND ACTIVATING FACTOR FOR EOSINOPHILS. Journal of Allergy and Clinical Immunology. 314-314. 1993
- TRANSFORMING GROWTH-FACTOR-BETA (TGF-BETA) ABROGATES THE SURVIVAL PROLONGING EFFECT OF IL-3, IL-5 AND GM-CSF ON EOSINOPHILS. Journal of Allergy and Clinical Immunology. 175-175. 1993
- EFFECT OF 8 KD FAMILY OF CYTOKINES ON BASOPHIL MAST-CELL HISTAMINE-RELEASE - MACROPHAGE INFLAMMATORY PROTEIN-1 (MIP-1) HAS HISTAMINE RELEASING ACTIVITY. Clinical Research. A229-A229. 1992
- IL-8 AND RANTES INHIBIT MONOCYTE CHEMOTACTIC AND ACTIVATING FACTOR (MCAF)-INDUCED HISTAMINE-RELEASE FROM PURIFIED BASOPHILS. FASEB Journal. A2005-A2005. 1992
- MONOCYTE CHEMOTACTIC AND ACTIVATING FACTOR (MCAF) MONOCYTE CHEMOATTRACTANT PROTEIN-1 (MCP-1) IS A POTENT SECRETAGOGUE FOR BASOPHILS. Journal of Allergy and Clinical Immunology. 307-307. 1992
- HISTAMINE-RELEASE INHIBITORY FACTORS (HRIF) AND HISTAMINE RELEASING FACTORS (HRF) IN BRONCHOALVEOLAR LAVAGE (BAL) FLUIDS. Journal of Allergy and Clinical Immunology. 236-236. 1989