Communication between gastrointestinal bacteria and the nervous system Academic Article uri icon

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abstract

  • In the past few years, intestinal microbiota has emerged as a novel target for the treatment of gut-brain axis alterations. These include functional gastrointestinal disorders, such as irritable bowel syndrome (IBS), which can be comorbid with stress-related psychiatric conditions. Thus, modulation of the microbiota (e.g. with the use of probiotics) could be proposed as a novel strategy not only for the treatment of IBS but also as an adjuvant for psychiatric treatment of anxiety and depression.

authors

  • Bravo, Javier A
  • Julio-Pieper, Marcela
  • Forsythe, Paul
  • Kunze, Wolfgang
  • Dinan, Timothy G
  • Bienenstock, John
  • Cryan, John F

publication date

  • December 2012