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Journal article

Communication between gastrointestinal bacteria and the nervous system

Abstract

In the past few years, intestinal microbiota has emerged as a novel target for the treatment of gut-brain axis alterations. These include functional gastrointestinal disorders, such as irritable bowel syndrome (IBS), which can be comorbid with stress-related psychiatric conditions. Thus, modulation of the microbiota (e.g. with the use of probiotics) could be proposed as a novel strategy not only for the treatment of IBS but also as an adjuvant for psychiatric treatment of anxiety and depression.

Authors

Bravo JA; Julio-Pieper M; Forsythe P; Kunze W; Dinan TG; Bienenstock J; Cryan JF

Journal

Current Opinion in Pharmacology, Vol. 12, No. 6, pp. 667–672

Publisher

Elsevier

Publication Date

January 1, 2012

DOI

10.1016/j.coph.2012.09.010

ISSN

1471-4892

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