Journal article
Expression of Ets-related Transcription Factors and Matrix Metalloproteinase Genes in Human Breast Cancer Cells
Abstract
The expression levels of ets and MMP genes was examined in two breast cancer cell lines of differing invasive potential. The more invasive MDA-MB-231 cell line had higher levels of Ets-1, Ets-2, PEA3, ERM, Tel, Net, MMP-13 and -14 mRNA than MCF-7 cells. MMP-1, -3 and -16 mRNAs were expressed equally. TPA stimulated MMP-1, -9 and TIMP-1 mRNA expression in both cell lines. MMP-2 and MMP-7 mRNAs were not detected in either cell line. The Ets-1 …
Authors
Barrett JM; Puglia MA; Singh G; Tozer RG
Journal
Breast Cancer Research and Treatment, Vol. 72, No. 3, pp. 227–232
Publisher
Springer Nature
Publication Date
April 2002
DOI
10.1023/a:1014993006190
ISSN
0167-6806