Journal article
Extracellular matrix regulates human airway smooth muscle cell migration
Abstract
Extracellular matrix proteins regulate the survival and proliferation of smooth muscle cells. Their effect on airway smooth muscle cell migration is not known. Their role in leukotriene-primed (0.1 microM leukotriene E4) chemotaxis of cultured human airway smooth muscle cells towards platelet-derived growth factor BB (1 ng.mL(-1)) was investigated. Migration of cells was greater on membranes coated with collagens III and V and fibronectin …
Authors
Parameswaran K; Radford K; Zuo J; Janssen LJ; O'Byrne PM; Cox PG
Journal
European Respiratory Journal, Vol. 24, No. 4, pp. 545–551
Publisher
European Respiratory Society (ERS)
Publication Date
October 2004
DOI
10.1183/09031936.04.00113103
ISSN
0903-1936