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Mesoscale characterization of osseointegration...
Journal article

Mesoscale characterization of osseointegration around an additively manufactured genistein-coated implant

Abstract

Given the hierarchical nature of bone and bone interfaces, osseointegration, namely the formation of a direct bone-implant contact, is best evaluated using a multiscale approach. However, a trade-off exists between field of view and spatial resolution, making it challenging to image large volumes with high resolution. In this study, we combine established electron microscopy techniques to probe bone-implant interfaces at the microscale and …

Authors

Micheletti C; DiCecco L-A; Deering J; Chen W; Ervolino da Silva AC; Shah FA; Palmquist A; Okamoto R; Grandfield K

Journal

Scientific Reports, Vol. 14, No. 1,

Publisher

Springer Nature

DOI

10.1038/s41598-024-66058-1

ISSN

2045-2322