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Cerebral microbleeds and asundexian in...
Journal article

Cerebral microbleeds and asundexian in non-cardioembolic ischemic stroke: Secondary analyses of the PACIFIC-STROKE randomized trial

Abstract

BACKGROUND AND AIMS: Cerebral microbleeds are magnetic imaging resonance (MRI) markers of hemorrhage-prone cerebral small vessel disease that predict future risk of ischemic stroke and intracranial hemorrhage (ICrH). There exist concerns about the net benefit of antithrombotic therapy in patients with microbleeds. We aimed to investigate the effects of an oral factor-XIa inhibitor (asundexian), that is hypothesized to inhibit thrombosis without …

Authors

Balali P; Hart RG; Smith EE; Saad F; Colorado P; Lemmens R; De Marchis GM; Caso V; Xu L; Heenan L

Journal

International Journal of Stroke, Vol. 19, No. 5, pp. 526–535

Publisher

SAGE Publications

Publication Date

June 2024

DOI

10.1177/17474930231216339

ISSN

1747-4930