Journal article
Post Hoc Analyses of a Randomized Controlled Trial for the Effect of Pharmacist Deprescribing Intervention on the Anticholinergic Burden in Frail Community-Dwelling Older Adults
Abstract
OBJECTIVES: Anticholinergic burden is detrimental to cognitive health. Multiple studies found that a high anticholinergic burden is associated with an increased risk for dementia, changes to the brain structure, function, and cognitive decline. We performed a post hoc analysis of a randomized controlled deprescribing trial. We compared the effect of the intervention on baseline anticholinergic burden across the treatment and control groups and …
Authors
Nishtala PS; Pickering JW; Bergler U; Mangin D; Hilmer SN; Jamieson H
Journal
Journal of the American Medical Directors Association, Vol. 24, No. 8, pp. 1253–1260
Publisher
Elsevier
Publication Date
August 2023
DOI
10.1016/j.jamda.2023.05.014
ISSN
1525-8610