Journal article
Notch-Induced miR-708 Antagonizes Satellite Cell Migration and Maintains Quiescence
Abstract
Critical features of stem cells include anchoring within a niche and activation upon injury. Notch signaling maintains skeletal muscle satellite (stem) cell quiescence by inhibiting differentiation and inducing expression of extracellular components of the niche. However, the complete spectrum of how Notch safeguards quiescence is not well understood. Here, we perform Notch ChIP-sequencing and small RNA sequencing in satellite cells and …
Authors
Baghdadi MB; Firmino J; Soni K; Evano B; Di Girolamo D; Mourikis P; Castel D; Tajbakhsh S
Journal
Cell Stem Cell, Vol. 23, No. 6, pp. 859–868.e5
Publisher
Elsevier
Publication Date
December 2018
DOI
10.1016/j.stem.2018.09.017
ISSN
1934-5909