Journal article
The relation between DNA methylation patterns and serum cytokine levels in community-dwelling adults: a preliminary study
Abstract
BackgroundThe levels of circulating cytokines fluctuate with age, acute illness, and chronic disease, and are predictive of mortality; this is also true for patterns of DNA (CpG) methylation. Given that immune cells are particularly sensitive to changes in the concentration of cytokines in their microenvironment, we hypothesized that serum levels of TNF, IL-6, IL-8 and IL-10 would correlate with genome-wide alterations in the DNA methylation …
Authors
Verschoor CP; McEwen LM; Kohli V; Wolfson C; Bowdish DM; Raina P; Kobor MS; Balion C
Journal
BMC Genomic Data, Vol. 18, No. 1,
Publisher
Springer Nature
Publication Date
December 2017
DOI
10.1186/s12863-017-0525-3
ISSN
1471-2156