Molecular Classification of Endometrial Cancers Using an Integrative DNA Sequencing Panel

BACKGROUND AND OBJECTIVES: Adoption of molecular classification in endometrial cancer (EC) into clinical practice remains challenging due to complexity in coordination of multiple assays. We aimed to develop a simple molecular technique to classify ECs into four subgroups using our custom-designed targeted sequencing panel. METHODS: Patients with newly diagnosed ECs were prospectively recruited from three cancer centres in Ontario, Canada. …