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DNA methylation changes in cord blood and the...
Journal article

DNA methylation changes in cord blood and the developmental origins of health and disease – a systematic review and replication study

Abstract

BackgroundEnvironmental exposures in utero which modify DNA methylation may have a long-lasting impact on health and disease in offspring. We aimed to identify and replicate previously published genomic loci where DNA methylation changes are attributable to in utero exposures in the NutriGen birth cohort studies Alliance.MethodsWe reviewed the literature to identify differentially methylated sites of newborn DNA which are associated with the …

Authors

Akhabir L; Stringer R; Desai D; Mandhane PJ; Azad MB; Moraes TJ; Subbarao P; Turvey SE; Paré G; Anand SS

Journal

BMC Genomics, Vol. 23, No. 1,

Publisher

Springer Nature

Publication Date

December 2022

DOI

10.1186/s12864-022-08451-6

ISSN

1471-2164