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Infliximab therapy in refractory sarcoidosis: a...
Journal article

Infliximab therapy in refractory sarcoidosis: a multicenter real-world analysis

Abstract

BackgroundInfliximab is a monoclonal antibody that binds and neutralizes circulating tumor necrosis factor-alpha, a key inflammatory cytokine in the pathophysiology of sarcoidosis. Despite the paucity of randomized clinical trials, infliximab is often considered a therapeutic option for refractory disease. Our study aimed to investigate the effectiveness of infliximab in patients with refractory sarcoidosis.MethodsSarcoidosis patients from …

Authors

Sakkat A; Cox G; Khalidi N; Larche M; Beattie K; Renzoni EA; Morar N; Kouranos V; Kolb M; Hambly N

Journal

Respiratory Research, Vol. 23, No. 1,

Publisher

Springer Nature

Publication Date

December 2022

DOI

10.1186/s12931-022-01971-5

ISSN

1465-9921