Journal article
Epigenetic Regulation of SOX9 by the NF‐κB Signaling Pathway in Pancreatic Cancer Stem Cells
Abstract
Pancreatic cancer is the fourth leading cause of cancer-related mortality in the world. Pancreatic cancer can be localized, locally advanced, or metastatic. The median 1- and 5-year survival rates are 25% and 6%, respectively. Epigenetic modifications such as DNA methylation play a significant role during both normal human development and cancer progression. To investigate epigenetic regulation of genes in the tumor-initiating population of …
Authors
Sun L; Mathews LA; Cabarcas SM; Zhang X; Yang A; Zhang Y; Young MR; Klarmann KD; Keller JR; Farrar WL
Journal
Stem Cells, Vol. 31, No. 8, pp. 1454–1466
Publisher
Oxford University Press (OUP)
Publication Date
August 1, 2013
DOI
10.1002/stem.1394
ISSN
1066-5099