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Intensified antiplatelet therapy in patients after...
Journal article

Intensified antiplatelet therapy in patients after percutaneous coronary intervention with high on‐treatment platelet reactivity: the OPTImal Management of Antithrombotic Agents (OPTIMA)‐2 Trial

Abstract

High on-treatment platelet reactivity (HOPR) is associated with increased risk of cardiovascular events in patients undergoing percutaneous coronary intervention (PCI). We randomised post-PCI patients with HOPR after 5 days of standard dual antiplatelet therapy (DAPT) to intensified therapy with aspirin 100 mg once daily in combination with either clopidogrel 150 mg once daily, clopidogrel 75 mg once daily plus cilostazol 100 mg twice daily, …

Authors

Ying L; Wang J; Li J; Teng J; Zhang X; Ullah I; Samee A; Xu K; Chen J; Xu L

Journal

British Journal of Haematology, Vol. 196, No. 2, pp. 424–432

Publisher

Wiley

Publication Date

January 2022

DOI

10.1111/bjh.17847

ISSN

0007-1048