Journal article
Perturbations to Homeostasis in Experimental Models Revealed Innate Pathways Driving Food Allergy
Abstract
While type 2 immunity has been conventionally viewed as beneficial against helminths, venoms, and poisons, and harmful in allergy, contemporary research has uncovered its critical role in the maintenance of homeostasis. The initiation of a type 2 immune response involves an intricate crosstalk between structural and immune cells. Structural cells react to physical and chemical tissue perturbations by secreting alarmins, which signal the innate …
Authors
Bruton K; Koenig JFE; Phelps A; Jordana M
Journal
Frontiers in Immunology, Vol. 11, ,
Publisher
Frontiers
DOI
10.3389/fimmu.2020.603272
ISSN
1664-3224