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Combination Antithrombotic Therapy for Reduction...
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Combination Antithrombotic Therapy for Reduction of Recurrent Ischemic Stroke in Intracranial Atherosclerotic Disease

Abstract

BACKGROUND: Stroke secondary to intracranial atherosclerotic disease (ICAD) is associated with high recurrence risk despite currently available secondary prevention strategies. In patients with systemic atherosclerosis, a significant reduction of stroke risk with no increase in intracranial or fatal hemorrhage was seen when rivaroxaban 2.5 mg twice daily was added to aspirin. However, there are no trials in ICAD using this combination. To …

Authors

Perera KS; Sharma MA; Eikelboom JW; Ng KKH; Field TS; Buck BH; Hill MD; Stotts G; Casaubon LK; Mandzia J

Volume

56

Pagination

pp. 380-389

Publisher

Wolters Kluwer

Publication Date

February 2025

DOI

10.1161/strokeaha.124.047715

Conference proceedings

Stroke

Issue

2

ISSN

0039-2499