Journal article
Remission of Type 2 Diabetes Following a Short-term Intervention With Insulin Glargine, Metformin, and Dapagliflozin
Abstract
OBJECTIVE: To examine diabetes remission following a short-term intensive metabolic intervention combining lifestyle and glucose-lowering approaches.
METHODS: We conducted an open-label, randomized controlled trial in 154 patients with type 2 diabetes up to 8 years in duration on 0 to 2 glucose-lowering medications. Participants were randomized to (a) a 12-week intensive intervention comprising lifestyle approaches and treatment with insulin …
Authors
McInnes N; Hall S; Sultan F; Aronson R; Hramiak I; Harris S; Sigal RJ; Woo V; Liu YY; Gerstein HC
Journal
The Journal of Clinical Endocrinology & Metabolism, Vol. 105, No. 8,
Publisher
The Endocrine Society
Publication Date
August 1, 2020
DOI
10.1210/clinem/dgaa248
ISSN
0021-972X
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AdultAgedAged, 80 and overBenzhydryl CompoundsBlood GlucoseDiabetes Mellitus, Type 2Drug Therapy, CombinationExerciseFemaleGlucosidesGlycated HemoglobinHealthy LifestyleHumansHypoglycemic AgentsInsulin GlargineMaleMetforminMiddle AgedRecurrenceRemission InductionSecondary PreventionTime FactorsTreatment Outcome