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Direct Thrombin Inhibitors
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Direct Thrombin Inhibitors

Abstract

Direct thrombin inhibitors may offer advantages over indirect thrombin inhibitors in the management of patients with acute coronary syndromes (ACS). Two direct thrombin inhibitors, hirudin and bivalirudin, have been investigated in Phase II and Phase III clinical trials. Based on the results of a meta-analysis of study data from 25,000 patients, hirudin appears to be more effective than unfractionated heparin (UFH) in the treatment of patients …

Authors

Anand S

Volume

29

Pagination

pp. 76-78

Publisher

Karger Publishers

Publication Date

1999

DOI

10.1159/000054117

Conference proceedings

Pathophysiology of Haemostasis and Thrombosis

Issue

Suppl 1

ISSN

1424-8832