Journal article
Cost-effective recruitment methods for a large randomised trial in people with diabetes: A Study of Cardiovascular Events iN Diabetes (ASCEND)
Abstract
BackgroundClinical trials require cost-effective methods for identifying, randomising, and following large numbers of people in order to generate reliable evidence. ASCEND (A Study of Cardiovascular Events iN Diabetes) is a randomised ‘2 × 2 factorial design’ study of aspirin and omega-3 fatty acid supplements for the primary prevention of cardiovascular events in people with diabetes; this study used central disease registers and a mail-based …
Authors
Aung T; Haynes R; Barton J; Cox J; Murawska A; Murphy K; Lay M; Armitage J; Bowman L; ASCEND Study Collaborative Group
Journal
Trials, Vol. 17, No. 1,
Publisher
Springer Nature
Publication Date
December 2016
DOI
10.1186/s13063-016-1354-9
ISSN
1468-6708
Associated Experts
Fields of Research (FoR)
Sustainable Development Goals (SDG)
Medical Subject Headings (MeSH)
AspirinCardiovascular DiseasesConsent FormsCost-Benefit AnalysisDiabetes MellitusDietary SupplementsFatty Acids, Omega-3HumansPatient SelectionPlatelet Aggregation InhibitorsPostal ServicePrimary PreventionRegistriesResearch Support as TopicSample SizeSurveys and QuestionnairesTime FactorsTreatment OutcomeUnited Kingdom