Journal article
Higher anti-depressant dose and major adverse outcomes in moderate chronic kidney disease: a retrospective population-based study
Abstract
BackgroundMany older patients have chronic kidney disease (CKD), and a lower dose of anti-depressants paroxetine, mirtazapine and venlafaxine is recommended in patients with CKD to prevent drug accumulation from reduced elimination. Using information available in large population-based healthcare administrative databases, we conducted this study to determine if ignoring the recommendation and prescribing a higher versus lower dose of …
Authors
Dev V; Dixon SN; Fleet JL; Gandhi S; Gomes T; Harel Z; Jain AK; Shariff SZ; Tawadrous D; Weir MA
Journal
BMC Nephrology, Vol. 15, No. 1,
Publisher
Springer Nature
Publication Date
12 2014
DOI
10.1186/1471-2369-15-79
ISSN
1471-2369