Journal article
Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma
Abstract
BACKGROUND: Papillary renal-cell carcinoma, which accounts for 15 to 20% of renal-cell carcinomas, is a heterogeneous disease that consists of various types of renal cancer, including tumors with indolent, multifocal presentation and solitary tumors with an aggressive, highly lethal phenotype. Little is known about the genetic basis of sporadic papillary renal-cell carcinoma, and no effective forms of therapy for advanced disease exist.
Authors
Linehan WM; Spellman PT; Ricketts CJ; Creighton CJ; Fei SS; Davis C; Wheeler DA; Murray BA; Schmidt L; Vocke CD
Journal
New England Journal of Medicine, Vol. 374, No. 2, pp. 135–145
Publisher
Massachusetts Medical Society
Publication Date
January 14, 2016
DOI
10.1056/nejmoa1505917
ISSN
0028-4793