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- A huntingtin-mediated fast stress response halting endosomal trafficking is defective in Huntington's disease Journal Articles
- A patient-derived cellular model for Huntington’s disease reveals phenotypes at clinically relevant CAG lengths Journal Articles
- A stress sensitive ER membrane-association domain in Huntingtin protein defines a potential role for Huntingtin in the regulation of autophagy Journal Articles
- Canadian Association of Neurosciences Review: Polyglutamine Expansion Neurodegenerative Diseases Journal Articles
- DNA Repair Signaling of Huntingtin: The Next Link Between Late-Onset Neurodegenerative Disease and Oxidative DNA Damage Journal Articles
- Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice Journal Articles
- High-mobility group box 1 links sensing of reactive oxygen species by huntingtin to its nuclear entry Journal Articles
- Huntingtin N17 domain is a reactive oxygen species sensor regulating huntingtin phosphorylation and localization Journal Articles
- Huntingtin contains a highly conserved nuclear export signal Journal Articles
- Huntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicity Journal Articles
- Huntingtin is a scaffolding protein in the ATM oxidative DNA damage response complex Journal Articles
- Huntingtin structure is orchestrated by HAP40 and shows a polyglutamine expansion-specific interaction with exon 1 Journal Articles
- Hypothesis: huntingtin may function in membrane association and vesicular traffickingThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB — Membrane Proteins in Health and Disease. Conferences
- Identification of a Karyopherin β1/β2 Proline-Tyrosine Nuclear Localization Signal in Huntingtin Protein Journal Articles
- Inhibition of Metabotropic Glutamate Receptor Signaling by the Huntingtin-binding Protein Optineurin Journal Articles
- Kinase inhibitors modulate huntingtin cell localization and toxicity Journal Articles
- Live cell imaging and biophotonic methods reveal two types of mutant huntingtin inclusions Journal Articles
- Mutant huntingtin causes defective actin remodeling during stress: defining a new role for transglutaminase 2 in neurodegenerative disease Journal Articles
- Nucleocytoplasmic trafficking and transcription effects of huntingtin in Huntington's disease Journal Articles
- PRMT5 promotes full-length HTT expression by repressing multiple proximal intronic polyadenylation sites. Journal Articles
- Poly ADP-ribose signaling is dysregulated in Huntington disease. Journal Articles
- Polyglutamine domain flexibility mediates the proximity between flanking sequences in huntingtin Journal Articles
- Recent Microscopy Advances and the Applications to Huntington’s Disease Research Journal Articles
- Revisiting huntingtin activity and localization signals in the context of protein structure. Journal Articles
- Shedding a new light on Huntington’s disease: how blood can both propagate and ameliorate disease pathology Journal Articles
- Targeting TEAD/YAP-transcription-dependent necrosis, TRIAD, ameliorates Huntington’s disease pathology Journal Articles
- The huntingtin N17 domain is a multifunctional CRM1 and Ran-dependent nuclear and cilial export signal Journal Articles