Genes, BRCA1 Concept

subject area of

• BRCA1 and BRCA2 Mutation Carriers, Oral Contraceptive Use, and Breast Cancer Before Age 50  Journal Articles
• A role for the TGFβ-Par6 polarity pathway in breast cancer progression  Journal Articles
• A significant response to neoadjuvant chemotherapy in BRCA1/2 related breast cancer  Journal Articles
• A unique BRCA1 mutation identified in Mongolia  Journal Articles
• Androgens and Estrogens in the Etiology and Prevention of Breast Cancer  Conferences
• Application of Breast Cancer Risk Prediction Models in Clinical Practice  Journal Articles
• Association of breast cancer risk in BRCA1 and BRCA2 mutation carriers with genetic variants showing differential allelic expression: identification of a modifier of breast cancer risk at locus 11q22.3  Journal Articles
• BRCA1, BRCA2 and breast cancer: a concise clinical review.  Journal Articles
• Breast and ovarian cancer risk perception after prophylactic salpingo‐oophorectomy due to an inherited mutation in the BRCA1 or BRCA2 gene  Journal Articles
• Breast cancer risk after age 60 among BRCA1 and BRCA2 mutation carriers  Journal Articles
• CK8/18 expression, the basal phenotype, and family history in identifying BRCA1‐associated breast cancer in the Ontario site of the Breast Cancer Family Registry  Journal Articles
• Clinical Management Recommendations for Surveillance and Risk-Reduction Strategies for Hereditary Breast and Ovarian Cancer Among Individuals Carrying a Deleterious BRCA1 or BRCA2 Mutation  Journal Articles
• Clinical Next-Generation Sequencing Pipeline Outperforms a Combined Approach Using Sanger Sequencing and Multiplex Ligation-Dependent Probe Amplification in Targeted Gene Panel Analysis  Journal Articles
• Contralateral Breast Cancer in BRCA1 and BRCA2 Mutation Carriers  Journal Articles
• Data sharing as a national quality improvement program: reporting on BRCA1 and BRCA2 variant-interpretation comparisons through the Canadian Open Genetics Repository (COGR)  Journal Articles
• Diabetes and breast cancer among women with BRCA1 and BRCA2 mutations  Journal Articles
• Does family history predict the age at onset of new breast cancers in BRCA1 and BRCA2 mutation‐positive families?  Journal Articles
• Double heterozygosity for germline mutations in BRCA1 and p53 in a woman with early onset breast cancer  Journal Articles
• Duration of tamoxifen use and the risk of contralateral breast cancer in BRCA1 and BRCA2 mutation carriers  Journal Articles
• Expression profiling of familial breast cancers demonstrates higher expression of FGFR2 in BRCA2-associated tumors  Journal Articles
• Familial ovarian cancer.  Journal Articles
• Family system characteristics and psychological adjustment to cancer susceptibility genetic testing: a prospective study  Journal Articles
• Gain of function mutant p53 proteins cooperate with E2F4 to transcriptionally downregulate RAD17 and BRCA1 gene expression  Journal Articles
• Germline BRCA1 Mutations and a Basal Epithelial Phenotype in Breast Cancer  Journal Articles
• Glomeruloid microvascular proliferation is associated with p53 expression, germline BRCA1 mutations and an adverse outcome following breast cancer  Journal Articles
• Hormone Therapy and the Risk of Breast Cancer in BRCA1 Mutation Carriers  Journal Articles
• Impact of germline BRCA1 mutations and overexpression of p53 on prognosis and response to treatment following breast carcinoma  Journal Articles
• Incidence of endometrial cancer in BRCA mutation carriers.  Journal Articles
• Infertility, treatment of infertility, and the risk of breast cancer among women with BRCA1 and BRCA2 mutations: a case–control study  Journal Articles
• Influence of Tertiary paleoenvironmental changes on the diversification of South American mammals: a relaxed molecular clock study within xenarthrans.  Journal Articles
• International trends in the uptake of cancer risk reduction strategies in women with a BRCA1 or BRCA2 mutation  Journal Articles
• International variation in rates of uptake of preventive options in BRCA1 and BRCA2 mutation carriers  Journal Articles
• Is Uterine Papillary Serous Adenocarcinoma a Manifestation of the Hereditary Breast–Ovarian Cancer Syndrome?  Journal Articles
• MRI Surveillance and Breast Cancer Mortality in Women With BRCA1 and BRCA2 Sequence Variations  Journal Articles
• Management of the BRCA Mutation Carrier or High-Risk Patient  Journal Articles
• Molecular Phylogeny of Living Xenarthrans and the Impact of Character and Taxon Sampling on the Placental Tree Rooting  Journal Articles
• Molecular phylogenetics unveils the ancient evolutionary origins of the enigmatic fairy armadillos  Journal Articles
• Olaparib tablets as maintenance therapy in patients with platinum-sensitive relapsed ovarian cancer and a BRCA1/2 mutation (SOLO2/ENGOT-Ov21): a final analysis of a double-blind, randomised, placebo-controlled, phase 3 trial  Journal Articles
• Olaparib tablets as maintenance therapy in patients with platinum-sensitive, relapsed ovarian cancer and a BRCA1/2 mutation (SOLO2/ENGOT-Ov21): a double-blind, randomised, placebo-controlled, phase 3 trial  Journal Articles
• Predictors of mammographic density among women with a strong family history of breast cancer  Journal Articles
• Prognosis of BRCA-associated breast cancer: a summary of evidence  Journal Articles
• Prophylactic Mastectomy for Women withBRCA1andBRCA2Mutations — Facts and Controversy  Journal Articles
• Radiotherapy for Breast Cancer  Journal Articles
• Rapid progression of prostate cancer in men with a BRCA2 mutation  Journal Articles
• Re: Magnetic Resonance Imaging and Mammography in Women With a Hereditary Risk of Breast Cancer  Journal Articles
• Refined histopathological predictors of BRCA1 and BRCA2mutation status: a large-scale analysis of breast cancer characteristics from the BCAC, CIMBA, and ENIGMA consortia  Journal Articles
• Risk factors for ovarian cancer and early-onset breast cancer in Mongolia.  Journal Articles
• Risk-reducing mastectomy and breast cancer mortality in women with a BRCA1 or BRCA2 pathogenic variant: an international analysis  Journal Articles
• Selecting a BRCA risk assessment model for use in a familial cancer clinic  Journal Articles
• Should platinum-based chemotherapy be preferred for germline BReast CAncer genes (BRCA) 1 and 2-mutated pancreatic ductal adenocarcinoma (PDAC) patients? A systematic review and meta-analysis  Journal Articles
• Tamoxifen and contralateral breast cancer in BRCA1 and BRCA2 carriers: An update  Journal Articles
• Tamoxifen and the risk of breast cancer in women with a BRCA1 or BRCA2 mutation  Journal Articles
• Ten-Year Multi-Institutional Results of Breast-Conserving Surgery and Radiotherapy in BRCA1/2-Associated Stage I/II Breast Cancer  Journal Articles
• The Fallopian Tube as the Origin of High Grade Serous Ovarian Cancer: Review of a Paradigm Shift  Journal Articles
• The Prognostic Implication of the Basal-Like (Cyclin Ehigh/p27low/p53+/Glomeruloid-Microvascular-Proliferation+) Phenotype of BRCA1 -Related Breast Cancer  Journal Articles
• The association between smoking and cancer incidence in BRCA1 and BRCA2 mutation carriers  Journal Articles
• The impact of prophylactic salpingo-oophorectomy on menopausal symptoms and sexual function in women who carry a BRCA mutation  Journal Articles
• The impact of prophylactic salpingo‐oophorectomy on quality of life and psychological distress in women with a BRCA mutation  Journal Articles