Journal article
The Fallopian Tube as the Origin of High Grade Serous Ovarian Cancer: Review of a Paradigm Shift
Abstract
Research published over the past 10 years has suggested that most "ovarian cancer," and specifically the high-grade serous carcinoma (HGSC) subtype of ovarian cancer, actually originates in the fallopian tube. In this review, we examine the evidence supporting the tubal origin hypothesis for HGSC, and discuss the clinical implications of our improved understanding of the pathogenesis of ovarian cancer. We searched Medline R and Medline …
Authors
Reade CJ; McVey RM; Tone AA; Finlayson SJ; McAlpine JN; Fung-Kee-Fung M; Ferguson SE
Journal
Journal of Obstetrics and Gynaecology Canada, Vol. 36, No. 2, pp. 133–140
Publisher
Elsevier
Publication Date
February 2014
DOI
10.1016/s1701-2163(15)30659-9
ISSN
1701-2163