selected scholarly activity
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books
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chapters
- Cannabidiolic acid (CBDA), features and profiles: Anti-hyperalgesic effects. 283-296. 2023
- Chapter 23 Cannabidiolic acid (CBDA), features and profiles: Anti-hyperalgesic effects. 283-296. 2023
- Cancer and Angiogenesis. 39-54. 2016
- Cancer-Induced Edema/Lymphedema. 85-103. 2016
- Cancer-Induced Fatigue and Cachexia. 147-174. 2016
- Cancer-Induced Inflammation. 73-84. 2016
- Cancer-Induced Neurogenesis. 55-71. 2016
- Cancer-Induced Pain. 129-145. 2016
- Conclusion. 211-212. 2016
- Oncodynamic Changes in Skeleton. 175-209. 2016
- Oncodynamic Effect of Cancer on Depression. 105-127. 2016
- The Disrupted Steady-State: Tipping the Balance in Favour of Cancer. 1-37. 2016
- Bone Metastasis and Pathological Fractures. Cancer Drug Discovery and Development. 229-241. 2005
- Cell Adhesion Molecules in Tumor Metastasis. Cancer Drug Discovery and Development. 133-146. 2005
- Overview. Cancer Drug Discovery and Development. 3-12. 2005
- Role of TGF-β and IGF in Tumor Progression and Bone Metastases. Cancer Drug Discovery and Development. 59-74. 2005
- Roles of Immune-Cell-Derived Matrix Metalloproteinases in Tumor Growth and Metastasis. Cancer Drug Discovery and Development. 87-106. 2005
- Use of Tetracyclines for Bone Metastases. Cancer Drug Discovery and Development. 293-303. 2005
- Comparative Morphometric Study on Bone Remodeling in Human Specimens and in Experimental Models of Metastatic Bone Disease. Cancer Metastasis - Biology and Treatment. 31-48. 2004
- Potential Therapeutic Targets for Bone Metastasis. Cancer Metastasis - Biology and Treatment. 187-210. 2004
- Role of Matrix Metalloproteinases in Bone Metastasis from Human Breast and Prostate Cancer. Cancer Metastasis - Biology and Treatment. 241-276. 2004
- Viral Infection and Xenobiotic Metabolism. 97-102. 1984
- Oxidative Stress and Glutamate Release in Glioma
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conferences
- Hyperelastic Bone Composite: A Novel 3D-printed Biomaterial Ink used for Spinal Fusion.. Journal of Bone and Mineral Research. S223-S224. 2017
- Abstract P3-03-13: Chronic inhibition of signal transducer and activator of transcription 3/5 in treatment-resistant human breast cancer cell subtypes: Convergence on the reactive oxyten species/SUMOylation pathway and its effects on xCT expression and system xc- activity. Cancer Research. 2017
- A Novel Pre-clinical Model of Cancer-Induced Depression. Biological Psychiatry. 54S-54S. 2015
- Abstract P5-07-05: Regulation of system Xc- by signal transducer and activator of transcription 3 and 5 in human breast cancer cells. Cancer Research. 2015
- Abstract 3233: Targeting system xc- in breast cancer cells: Development of novel therapeutics. Cancer Research. 3233-3233. 2014
- Abstract 3687: Analgesic effects of capsazepine on a mouse model of bone cancer pain. Cancer Research. 3687-3687. 2014
- Abstract 506: H2O2 upregulates xCT in human breast cancer cells via NRF-2. Cancer Research. 506-506. 2014
- Abstract 5392: High-throughput screening of compounds for targeting system Xc(-) in human breast cancer cells. Cancer Research. 5392-5392. 2014
- Abstract 5157: Prolactin plays a role in regulating fatty acid synthesis and metabolism in the prostate cancer cell line PC-3. Cancer Research. 5157-5157. 2012
- THE ANTI-DIABETIC DRUG METFORMIN SENSITIZES HUMAN NON-SMALL CELL LUNG CANCER (NSCLC) XENOGRAFTS TO IONIZING RADIATION.. Journal of Thoracic Oncology. S571-S572. 2011
- Abstract 2491: Metformin sensitizes human lung cancer xenografts to ionizing radiation: Response of the AMPK pathway. Cancer Research. 2491-2491. 2011
- Abstract 4071: Sestrins modulate the expression of the metabolic stress sensor AMPK in breast cancer cells. Cancer Research. 4071-4071. 2011
- Examination of the mechanism(s) of cancer-induced bone pain in animal models. Bone. S39-S39. 2011
- Glutamate release in bone metastasis. Bone. S32-S32. 2011
- The role of parathyroid hormone-related protein in giant cell tumour of bone. Bone. S48-S48. 2011
- Abstract P4-03-02: Establishing a Relationship between Breast Cancer, Prolactin and Altered Fat Metabolism. Cancer Research. 2010
- Combinations of Epigenetic Modifying Agents Accentuate Retinoid-Mediated Gene Expression Over Single Agent Therapies In Acute Myelogenous Leukemia Cells.. Blood. 1035-1035. 2010
- Abstract 3694: The mitochondrial FAD-linked glycerol-3-phosphate dehydrogenase as an inhibitory target for cancer therapeutics. Cancer Research. 3694-3694. 2010
- Molecular mechanisms associated with ALA-PDT of brain tumor cells. Proceedings of SPIE - The International Society for Optical Engineering. 2009
- A targeted, high-throughput screening approach for inhibitors of reactive oxygen species in prostate cancer cells.. Cancer Research. 2009
- Characterization of glutamate transporters in cancer cells: Implications on normal bone formation.. Cancer Research. 2009
- Effect of Prostate-Specific Antigen on mouse bone metastasis from prostate cancer. Cancer Research. 2009
- Metastatic cancer cells release glutamate to disrupt bone turnover.. Cancer Research. 2009
- Metronomic ALA-PDT induces apoptosis through the inhibition of LT/#946;R. Cancer Research. 2009
- Metronomic ALA-PDT induces apoptosis through the inhibition of LT\#946;R. Cancer Research. 2009
- Prostate cancer induced bone metastasis and related nociceptive alterations in an animal model. Cancer Research. 2009
- Synthesis and in vitro screening of uPAR-targeting peptides for SPECT imaging of aggressive tumors. Journal of Nuclear Medicine. 2009
- The pathophysiology of stromal cell-derived PTHrP in giant cell tumor of bone. Cancer Research. 2009
- Construction of tissue micro array from prostate needle biopsies using vertical clustering re-arrangement technique. Histopathology. 274-275. 2008
- INVESTIGATING RESVERATROL IN COMBINATION WITH RADIATION IN PROSTATE CANCER. Radiotherapy and Oncology. S37-S37. 2008
- LOVASTATIN SENSITIZES NON-SMALL CELL LUNG CANCER (NSCLC) CELLS TO RADIATION; POSSIBLE INVOLVEMENT OF THE AKT SIGNALING PATHWAY. Radiotherapy and Oncology. S2-S2. 2008
- Construction of tissue micro array from prostate needle biopsies using vertical clustering re-arrangement technique. Journal of Clinical Oncology. 22205-22205. 2008
- Lower plasma adiponectin levels are associated with larger tumor size and metastasis in clear cell carcinoma of the kidney. Journal of Clinical Oncology. 22225-22225. 2008
- INTER-RELATED EFFECTS OF ANDROGENS, FATTY ACIDS AND OXIDATIVE STRESS IN PROSTATE CANCER - A MECHANISTIC SUPPORT FOR PREVENTION STRATEGIES. Investigative Urology. 42-42. 2008
- Exploration of the mechanisms of bone metastasis (BM) growth and resistance to bisphosphonate (BP) therapy in patients with metastatic breast cancer (MBC). Clinical and Experimental Metastasis. 51-52. 2008
- Immunohistochemistry for phosphorylated EGF receptor predicts survival and phosphorylated ERK predicts tumor response to chemo-radiotherapy in unresectable, locally advanced non-small cell lung cancer patients. Laboratory Investigation. 339A-339A. 2008
- Immunohistochemistry for phosphorylated EGF receptor predicts survival and phosphorylated ERK predicts tumor response to chemoradiotherapy in unresectable, locally advanced non-small cell lung cancer patients. Modern Pathology. 339A-339A. 2008
- Plasma membrane and cytoplasmic activated EGF receptor predicts survival and cytoplasmic activated Erk predicts tumour response in locally advanced NSCLC patients treated with chemo-radiotherapy. Radiotherapy and Oncology. S57-S57. 2007
- Mechanisms of bone metastasis (BM) growth in patients with metastatic breast cancer (MBC): An exploratory study. Journal of Clinical Oncology. 2007
- In vitro analysis of human femoral cancellous bone as a viable source of osteoprogenitor cells and the effects of bone morphogenetic protein 2 and doxycycline on their differentiation into bone forming colonies. Bone. S167-S167. 2007
- Properties of the Stromal Cell in Giant Cell Tumor of Bone. Clinical Orthopaedics and Related Research. 8-13. 2007
- 1289: Lower Plasma Adiponectin Levels as a Potential Biomarker for Renal Cell Carcinoma. Investigative Urology. 424-425. 2007
- Ontario tumour bank initiative at Hamilton Health Sciences and the Juravinski Cancer Centre. Modern Pathology. 52-52. 2006
- Downregulation of galectin-1 in androgen-independent prostate cancer cells leads to impairment of survival and reduction in invasive capacity. Cancer Research. 2006
- Role of IGFBP-3 in the proliferation of MDA-MB-231 breast carcinoma cells in bone metastasis. Cancer Research. 2006
- Spinal astrogliosis in an animal model of cancer-induced bone pain. Cancer Research. 2006
- Treatment of breast cancer cells with combination therapy.. Cancer Research. 2006
- Why do patients with metastatic breast cancer (MBC) continue to have bone destruction despite bisphosphonate (BP) use? A pathologic review. Bone. 81-81. 2006
- P-126 Activation of tyrosine kinase receptors and intracellular signal mediators in NSCLC tumors. Lung Cancer. S148-S148. 2005
- The effect of doxycycline on bone turnover and tumor markers in breast cancer (BC) patients with skeletal metastases. Journal of Clinical Oncology. 3198-3198. 2005
- The effect of doxycycline on bone turnover and tumor markers in breast cancer (BC) patients with skeletal metastases.. Journal of Clinical Oncology. 240S-240S. 2005
- A study examining epidermal growth factor receptor, p53, and Bcl-2 expression in patients with locally advanced squamous cell carcinoma of the head and neck treated with concomitant chemoradiotherapy. Lung Cancer. S82-S83. 2004
- A study examining epidermal growth factor receptor, p53, and Bcl-2 expression in patients with stage III and IV squamous cell carcinoma of the head and neck treated with concomitant chemo-radiotherapy.. Radiotherapy and Oncology. S40-S40. 2004
- Mitogen-activated protein kinase (MAPK) expression and activation in non-small cell lung cancer (NSCLC): Investigating their prognostic significance and role in radiation responses.. Radiotherapy and Oncology. S40-S41. 2004
- Treatment of bone metastasis with a combination of doxycycline and zoledronate. Journal of Bone and Mineral Research. 1596-1597. 2004
- Fibrinolytic profile and fibrin(ogen) degradation products (FDPs) in human ovarian cancer ascites fluid. The FASEB Journal. A196-A196. 2004
- Are mediated regulation of the transcription factor ETS-1. Free Radical Biology and Medicine. S74-S74. 2004
- Ets-1: A target of mitochondrial signaling via reactive oxygen species. Free Radical Biology and Medicine. S76-S76. 2003
- Histomorphometric analysis of bone remodelling in patients with metastatic breast carcinoma. Bone. S135-S135. 2001
- Upregulation of heat shock protein 27 plays a critical role in the resistance of HT29 cells to singlet oxygen-mediated photooxidation. Free Radical Biology and Medicine. S142-S142. 2001
- Pathophysiologic interactions in skeletal metastasis. Cancer. 2912-2918. 2000
- Mitochondria as a critical target for toxicity. In Vitro and Molecular Toxicology: Journal of Basic and Applied Research. 73-81. 1998
- Homocysteine alters mitochondrial gene expression, function and structure.. Blood. 1358-1358. 1997
- N-acetyl-L-cysteine (NAC) alters cell cycle progression in ovarian cancer cells of epithelial origin.. The FASEB Journal. 1665-1665. 1996
- The role of Bcl-2 expression in mediating cisplatinum resistance.. Blood. 3113-3113. 1995
- Studies of the significance of functional and structural changes in mitochondria in PhotofrinTM-photodynamic-therapy-resistant cells. Proceedings of SPIE - The International Society for Optical Engineering. 200-207. 1994
- TUMOUR MITOCHONDRIA AS A TARGET FOR CANCER CHEMOTHERAPY. PROCEEDINGS OF THE XVI INTERNATIONAL CANCER CONGRESS - FREE PAPERS AND POSTERS, TOMES 1-4. 2859-2863. 1994
- RELATIONSHIP BETWEEN MITOCHONDRIAL-DNA AND ALZHEIMERS-DISEASE. The FASEB Journal. A627-A627. 1993
- Mechanisms involved in the metastasis of cancer to bone. Breast Cancer Research and Treatment. 151-163. 1993
- BONE REMODELING RATE CORRELATES WITH BONE METASTASIS AND TUMOR-CELL GROWTH-INVIVO. The FASEB Journal. A1948-A1948. 1992
- RELATIONSHIP BETWEEN MTDNA AND MITOCHONDRIAL-FUNCTION. RECENT ADVANCES IN CELLULAR AND MOLECULAR BIOLOGY, VOL 2. 117-122. 1992
- Relationship between drug induced organ specific toxicity and mitochondrial genomic regulation and content. European Journal of Pharmacology. 1105-1106. 1990
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journal articles
- Computational modeling to study the impact of changes in Nav1.8 sodium channel on neuropathic pain. Frontiers in Computational Neuroscience. 18:1327986. 2024
- Doxycycline-Induced Changes in Circulating MMP or TIMP2 Levels Are Not Associated with Skeletal-Related Event-Free or Overall Survival in Patients with Bone Metastases from Breast Cancer. Cancers. 15:571-571. 2023
- Is chronic pain as an autoimmune disease?. Canadian Journal of Pain. 6. 2022
- Differences and Similarities in Spontaneous Activity Between Animal Models of Cancer-Induced Pain and Neuropathic Pain. Journal of Pain Research. Volume 15:3179-3187. 2022
- Effect of Early Treatment With Hydroxychloroquine or Lopinavir and Ritonavir on Risk of Hospitalization Among Patients With COVID-19. JAMA network open. 4:e216468-e216468. 2021
- A systematic review of the literature on the relationship between ACE2 and SARS-CoV infection in animal models. University of Toronto Medical Journal. 98:63-68. 2021
- Electrochemical sensing: A prognostic tool in the fight against COVID-19. TrAC. Trends in analytical chemistry. 136:116198-116198. 2021
- Sex differences in neuro(auto)immunity and chronic sciatic nerve pain. Biology of Sex Differences. 11:62. 2020
- Correction: Glutamate sensing in biofluids: recent advances and research challenges of electrochemical sensors. The Analyst. 145:4369-4371. 2020
- An evaluation of the anti‐hyperalgesic effects of cannabidiolic acid‐methyl ester in a preclinical model of peripheral neuropathic pain. British Journal of Pharmacology. 177:2712-2725. 2020
- Electrochemical Sensing of Cannabinoids in Biofluids: A Noninvasive Tool for Drug Detection. ACS Sensors. 5:620-636. 2020
- Glutamate sensing in biofluids: recent advances and research challenges of electrochemical sensors. The Analyst. 145:321-347. 2020
- <p>Applying Serum Cytokine Levels to Predict Pain Severity in Cancer Patients</p>. Journal of Pain Research. Volume 13:313-321. 2020
- Bone cancer-induced pain is associated with glutamate signalling in peripheral sensory neurons. Molecular Pain. 16:174480692091153-174480692091153. 2020
- Evaluation of the preclinical analgesic efficacy of naturally derived, orally administered oil forms of Δ9-tetrahydrocannabinol (THC), cannabidiol (CBD), and their 1:1 combination. PLoS ONE. 15:e0234176-e0234176. 2020
- Response to pregabalin and progesterone differs in male and female rat models of neuropathic and cancer pain. Canadian Journal of Pain. 4:39-58. 2020
- Evaluating the efficacy of cannabidiol to manage surgically induced neuropathic pain in a preclinical rat model: Are T cells a sexually dimorphic target?. Canadian Journal of Pain. 3:44-48. 2019
- STAT3 Inhibition in a Murine Model of Human Breast Cancer-Induced Bone Pain Delays Onset of Nociception. Canadian Journal of Pain. 3:69-69. 2019
- Spinal microglia contribute to cancer-induced pain through system xC −-mediated glutamate release. Pain Reports. 4:e738-e738. 2019
- <p>Activation of hippocampal microglia in a murine model of cancer-induced pain</p>. Journal of Pain Research. Volume 12:1003-1016. 2019
- <p>Effect of glutaminase inhibition on cancer-induced bone pain</p>. Breast Cancer: Targets and Therapy. Volume 11:273-282. 2019
- Inhibiting STAT3 in a murine model of human breast cancer-induced bone pain delays the onset of nociception. Molecular Pain. 15:174480691882347-174480691882347. 2019
- xCT knockdown in human breast cancer cells delays onset of cancer-induced bone pain. Molecular Pain. 15:174480691882218-174480691882218. 2019
- Biological Mechanisms of Cancer-Induced Depression. Frontiers in Psychiatry. 9:299. 2018
- Cancer pain and neuropathic pain are associated with Aβ sensory neuronal plasticity in dorsal root ganglia and abnormal sprouting in lumbar spinal cord. Molecular Pain. 14:174480691881009-174480691881009. 2018
- Functional effects of TrkA inhibition on system xC−-mediated glutamate release and cancer-induced bone pain. Molecular Pain. 14:174480691877646-174480691877646. 2018
- Preparation of tetrazine-containing [2 + 1] complexes of 99mTc and in vivo targeting using bioorthogonal inverse electron demand Diels–Alder chemistry. Dalton Transactions. 46:14691-14699. 2017
- Can killers be saviors?. Lupus. 26:903-908. 2017
- The complex roles of STAT3 and STAT5 in maintaining redox balance: Lessons from STAT-mediated xCT expression in cancer cells. Molecular and Cellular Endocrinology. 451:40-52. 2017
- Rat model of cancer-induced bone pain: changes in nonnociceptive sensory neurons in vivo. Pain Reports. 2:e603-e603. 2017
- Tumour-Derived Glutamate: Linking Aberrant Cancer Cell Metabolism to Peripheral Sensory Pain Pathways. Current Neuropharmacology. 15:620-636. 2017
- Behavioural Effects of Using Sulfasalazine to Inhibit Glutamate Released by Cancer Cells: A Novel target for Cancer-Induced Depression. Scientific Reports. 7:41382. 2017
- Identification of capsazepine as a novel inhibitor of system x<sub>c</sub><sup>−</sup> and cancer-induced bone pain. Journal of Pain Research. Volume 10:915-925. 2017
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RNA ‐sequencing profiles hippocampal gene expression in a validated model of cancer‐induced depression. Genes, Brain and Behavior. 15:711-721. 2016 - A phase 2 trial exploring the clinical and correlative effects of combining doxycycline with bone-targeted therapy in patients with metastatic breast cancer. Journal of Bone Oncology. 5:173-179. 2016
- Future directions for bone metastasis research – highlights from the 2015 bone and the Oncologist new updates conference (BONUS). Journal of Bone Oncology. 5:57-62. 2016
- Chronic Inhibition of STAT3/STAT5 in Treatment-Resistant Human Breast Cancer Cell Subtypes: Convergence on the ROS/SUMO Pathway and Its Effects on xCT Expression and System xc- Activity. PLoS ONE. 11:e0161202-e0161202. 2016
- Differences in electrophysiological properties of functionally identified nociceptive sensory neurons in an animal model of cancer-induced bone pain. Molecular Pain. 12:174480691662877-174480691662877. 2016
- Overview of Glutamatergic Dysregulation in Central Pathologies. Biomolecules. 5:3112-3141. 2015
- Depressive-like behaviours and decreased dendritic branching in the medial prefrontal cortex of mice with tumors: A novel validated model of cancer-induced depression. Behavioural Brain Research. 294:25-35. 2015
- Expression of xCT and activity of system xc− are regulated by NRF2 in human breast cancer cells in response to oxidative stress. Redox Biology. 5:33-42. 2015
- Signal transducer and activator of transcription 3 and 5 regulate system Xc- and redox balance in human breast cancer cells. Molecular and Cellular Biochemistry. 405:205-221. 2015
- Inhibitors of glutamate release from breast cancer cells; new targets for cancer-induced bone-pain. Scientific Reports. 5:8380. 2015
- The transcriptional responsiveness of LKB1 to STAT-mediated signaling is differentially modulated by prolactin in human breast cancer cells. BMC Cancer. 14:415. 2014
- Bone-targeted therapy for metastatic breast cancer-Where do we go from here? A commentary from the BONUS 8 meeting. Journal of Bone Oncology. 3:1-4. 2014
- Bone-targeted therapy for metastatic breast cancer—Where do we go from here? A commentary from the BONUS 8 meeting. Journal of Bone Oncology. 3:1-4. 2014
- Mitochondrial FAD-linked Glycerol-3-phosphate Dehydrogenase: A Target for Cancer Therapeutics. Pharmaceuticals. 7:192-206. 2014
- AMP-activated protein kinase (AMPK) beyond metabolism. Cancer Biology and Therapy. 15:156-169. 2014
- Cancer-Induced Oxidative Stress and Pain. Current Pain and Headache Reports. 18:384. 2014
- Inhibition of breast cancer-cell glutamate release with sulfasalazine limits cancer-induced bone pain. Pain. 155:28-36. 2014
- Ets-1 global gene expression profile reveals associations with metabolism and oxidative stress in ovarian and breast cancers. Cancer & Metabolism. 1:17. 2013
- Metformin inhibits growth and enhances radiation response of non-small cell lung cancer (NSCLC) through ATM and AMPK. British Journal of Cancer. 108:2021-2032. 2013
- Ets-1 regulates intracellular glutathione levels: key target for resistant ovarian cancer. Molecular Cancer. 12:138-138. 2013
- Giant cell tumor of bone: A basic science perspective. Bone. 52:238-246. 2013
- Mitochondria and Cancer. BioMed Research International. 2013:1-2. 2013
- Mitochondria and Cancer: Past, Present, and Future. BioMed Research International. 2013:1-10. 2013
- Oxidative stress and cancer pain. Canadian Journal of Physiology and Pharmacology. 91:31-37. 2013
- Chronic modulation of AMP-Kinase, Akt and mTOR pathways by ionizing radiation in human lung cancer xenografts. Radiation Oncology. 7:71. 2012
- PTHrP increases RANKL expression by stromal cells from giant cell tumor of bone. Journal of Orthopaedic Research. 30:877-884. 2012
- Ionizing radiation regulates the expression of AMP-activated protein kinase (AMPK) in epithelial cancer cells. Radiotherapy and Oncology. 102:459-465. 2012
- N-demethylation of cyamemazine via non-classical Polonovski reaction and its conjugation to bovine serum albumin. Bioorganic and Medicinal Chemistry Letters. 22:2160-2162. 2012
- T cells stimulate catabolic gene expression by the stromal cells from giant cell tumor of bone. Biochemical and Biophysical Research Communications. 419:719-723. 2012
- Glutamate Signaling in Healthy and Diseased Bone. Frontiers in Endocrinology. 3:89. 2012
- Liver kinase B1 expression (LKB1) is repressed by estrogen receptor alpha (ERα) in MCF-7 human breast cancer cells. Biochemical and Biophysical Research Communications. 417:1063-1068. 2012
- Sestrin2 Modulates AMPK Subunit Expression and Its Response to Ionizing Radiation in Breast Cancer Cells. PLoS ONE. 7:e32035-e32035. 2012
- Establishing a relationship between prolactin and altered fatty acid β-Oxidation via carnitine palmitoyl transferase 1 in breast cancer cells. BMC Cancer. 11:56. 2011
- Resveratrol enhances prostate cancer cell response to ionizing radiation. Modulation of the AMPK, Akt and mTOR pathways. Radiation Oncology. 6:144. 2011
- The role of TWIST as a regulator in giant cell tumor of bone. Journal of Cellular Biochemistry. 112:2287-2295. 2011
- Lovastatin Sensitizes Lung Cancer Cells to Ionizing Radiation: Modulation of Molecular Pathways of Radioresistance and Tumor Suppression. Journal of Thoracic Oncology. 6:439-450. 2011
- AP-1 as a Regulator of MMP-13 in the Stromal Cell of Giant Cell Tumor of Bone. Biochemistry Research International. 2011:1-7. 2011
- PTHrP Induces Autocrine/Paracrine Proliferation of Bone Tumor Cells through Inhibition of Apoptosis. PLoS ONE. 6:e19975-e19975. 2011
- Combinations of Epigenetic Modifying Agents Accentuate Retinoid-Mediated Gene Expression Over Single Agent Therapies In Acute Myelogenous Leukemia Cells. Blood. 116:2497-2497. 2010
- Characterization of a rat model of metastatic prostate cancer bone pain. Journal of Pain Research. 3:213-213. 2010
- Ets-1 Regulates Energy Metabolism in Cancer Cells. PLoS ONE. 5:e13565-e13565. 2010
- Evidence for the role of matrix metalloproteinase-13 in bone resorption by giant cell tumor of bone. Human Pathology. 41:1320-1329. 2010
- Extracellular glutamate alters mature osteoclast and osteoblast functions. Canadian Journal of Physiology and Pharmacology. 88:929-936. 2010
- Inter-related in vitro effects of androgens, fatty acids and oxidative stress in prostate cancer: A mechanistic model supporting prevention strategies. International Journal of Oncology. 37:761-766. 2010
- Ionizing Radiation Activates AMP-Activated Kinase (AMPK): A Target for Radiosensitization of Human Cancer Cells. International Journal of Radiation Oncology Biology Physics. 78:221-229. 2010
- Abstract 43: Role of Ets-1 in the regulation of energy metabolism in cancer cells. Cancer Research. 70:43-43. 2010
- A by-product of glutathione production in cancer cells may cause disruption in bone metabolic processesThis review is one of a selection of papers published in a Special Issue on Oxidative Stress in Health and Disease.. Canadian Journal of Physiology and Pharmacology. 88:197-203. 2010
- Mechanisms associated with mitochondrial-generated reactive oxygen species in cancerThis article is one of a selection of papers published in a Special Issue on Oxidative Stress in Health and Disease.. Canadian Journal of Physiology and Pharmacology. 88:204-219. 2010
- Cancer cells release glutamate via the cystine/glutamate antiporter. Biochemical and Biophysical Research Communications. 391:91-95. 2010
- Metronomic PDT and Cell Death Pathways. Methods in molecular biology (Clifton, N.J.). 635:65-78. 2010
- Matrix Metalloproteinase Activity in the Stromal Cell of Giant Cell Tumor of Bone. Open Bone Journal. 1:46-52. 2009
- Evaluation of single amino acid chelate derivatives and regioselective radiolabelling of a cyclic peptide for the urokinase plasminogen activator receptor. Nuclear Medicine and Biology. 36:907-917. 2009
- Cancer cell lines release glutamate into the extracellular environment. Clinical and Experimental Metastasis. 26:781-787. 2009
- Upregulation of MMP-13 via Runx2 in the stromal cell of Giant Cell Tumor of Bone. Bone. 45:377-386. 2009
- Collagenase expression and activity in the stromal cells from giant cell tumour of bone. Bone. 44:865-871. 2009
- Examination of the mechanisms of osteolysis in patients with metastatic breast cancer. Oncology Reports. 21:1153-1159. 2009
- Effect of Bone Morphogenetic Protein-2 and Doxycycline on the Differentiation of Osteoprogenitors from Human Femoral Bone. Open Bone Journal. 1:1-7. 2009
- Interactions of doxycycline with chemotherapeutic agents in human breast adenocarcinoma MDA-MB-231 cells. Anti-Cancer Drugs. 20:115-122. 2009
- In Vitro Survival of Nonsmall Cell Lung Cancer Cells Following Combined Treatment with Ionizing Radiation and Photofrin‐mediated Photodynamic Therapy. Photochemistry and Photobiology. 85:99-106. 2009
- Luciferase Therapeutic Microcapsules for Gene Therapy. Artificial Cells, Nanomedicine and Biotechnology. 37:235-244. 2009
- Discordance between Receptor Status in Primary and Metastatic Breast Cancer: an Exploratory Study of Bone and Bone Marrow Biopsies. Clinical Oncology. 20:763-768. 2008
- Role of IGF-1/IGF-1R in regulation of invasion in DU145 prostate cancer cells. Cancer Cell International. 8:10. 2008
- Lower Plasma Adiponectin Levels Are Associated with Larger Tumor Size and Metastasis in Clear-Cell Carcinoma of the Kidney. European Urology. 54:866-874. 2008
- Association of Phosphorylated Epidermal Growth Factor Receptor with Survival in Patients with Locally Advanced Non-small Cell Lung Cancer Treated with Radiotherapy. Journal of Thoracic Oncology. 3:716-722. 2008
- A robust strategy for the preparation of libraries of metallopeptides. A new paradigm for the discovery of targeted molecular imaging and therapy agents. Chemical Communications. 0:5532-5532. 2008
- Androgen‐dependent regulation of medium and long chain fatty acids uptake in prostate cancer. Prostate. 67:1330-1338. 2007
- Viral serpin, Serp-1, inhibits endogenous angiogenesis in the chicken chorioallantoic membrane model. Cardiovascular Pathology. 16:191-202. 2007
- Mechanisms of bone metastasis (BM) growth in patients with metastatic breast cancer (MBC): An exploratory study. Journal of Clinical Oncology. 25:1102-1102. 2007
- Effect of zoledronic acid on the doxycycline-induced decrease in tumour burden in a bone metastasis model of human breast cancer. British Journal of Cancer. 96:1526-1531. 2007
- Androgen Induces Adaptation to Oxidative Stress in Prostate Cancer: Implications for Treatment with Radiation Therapy. Neoplasia. 9:68-80. 2007
- Chronic hypoxia promotes an aggressive phenotype in rat prostate cancer cells. Free Radical Research. 41:788-797. 2007
- Increased expression of mitochondrial glycerophosphate dehydrogenase and antioxidant enzymes in prostate cancer cell lines/cancer. Free Radical Research. 41:1116-1124. 2007
- Human ovarian cancer ascites fluid contains a mixture of incompletely degraded soluble products of fibrin that collectively possess an antiangiogenic property. International Journal of Gynecological Cancer. 16:1536-1544. 2006
- Human ovarian cancer ascites fluid contains a mixture of incompletely degraded soluble products of fibrin that collectively possess an antiangiogenic property. International Journal of Gynecological Cancer. 16:1536-1544. 2006
- Effects of geldanamycin on HIF-1α mediated angiogenesis and invasion in prostate cancer cells. Prostate Cancer and Prostatic Diseases. 9:126-135. 2006
- Erratum: Effect of Herceptin on the development and progression of skeletal metastases in a xenograft model of human breast cancer. Oncogene. 25:492-492. 2006
- Relationships among tumor burden, tumor size, and the changing concentrations of fibrin degradation products and fibrinolytic factors in the pleural effusions of rabbits with VX2 lung tumors. Translational Research. 147:27-35. 2006
- ets‐1is transcriptionally up‐regulated by H2O2via an antioxidant response element. The FASEB Journal. 19:2085-2087. 2005
- Effect of Herceptin on the development and progression of skeletal metastases in a xenograft model of human breast cancer. Oncogene. 24:6657-6666. 2005
- Modulation of monocyte matrix metalloproteinase-2 by breast adenocarcinoma cells. Breast Cancer Research. 7:R661-R668. 2005
- High activity of mitochondrial glycerophosphate dehydrogenase and glycerophosphate-dependent ROS production in prostate cancer cell lines. Biochemical and Biophysical Research Communications. 333:1139-1145. 2005
- Inhibition by doxycycline of angiogenesis in the chicken chorioallantoic membrane (CAM). Cancer Chemotherapy and Pharmacology. 56:1-9. 2005
- P-125 p-38 MAPK, Erk and Akt expression and activation in NSCLCtumors; Subcellular distribution and radiographic response to radiotherapy. Lung Cancer. 49:S147-S148. 2005
- Regulation of the cell cycle in response to inhibition of mitochondrial generated energy. Biochemical and Biophysical Research Communications. 332:1122-1132. 2005
- Sci‐YIS Fri ‐ 03: Calculation of singlet oxygen dose from photosensitizer photobleaching during mTHPC or Photofrin photodynamic therapy in vitro. Medical Physics. 32:2419-2419. 2005
- Increased BNip3 and decreased mutant p53 in cisplatin-sensitive PDT-resistant HT29 cells. Biochemical and Biophysical Research Communications. 331:648-657. 2005
- Alterations in Mitochondrial and Apoptosis‐regulating Gene Expression in Photodynamic Therapy‐resistant Variants of HT29 Colon Carcinoma Cells¶. Photochemistry and Photobiology. 81:306-313. 2005
- Alterations in Mitochondrial and Apoptosis-regulating Gene Expression in Photodynamic Therapy-resistant Variants of HT29 Colon Carcinoma Cells¶. Photochemistry and Photobiology. 81:306-306. 2005
- Calculation of Singlet Oxygen Dose from Photosensitizer Fluorescence and Photobleaching During mTHPC Photodynamic Therapy of MLL Cells¶. Photochemistry and Photobiology. 81:196-205. 2005
- Re-expression of TSLC1 in a non-small-cell lung cancer cell line induces apoptosis and inhibits tumor growth. Oncogene. 23:5632-5642. 2004
- Matrix metalloproteinases and the immune response. Clinical and Applied Immunology Reviews. 4:295-319. 2004
- Role of the transcription factor Ets-1 in cisplatin resistance. Molecular Cancer Therapeutics. 3:823-832. 2004
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