Journal article
Lithium and hydrocortisone interactions on cell growth and gene expression in human promyelocytic leukemia (HL60)
Abstract
Lithium (Li) and hydrocortisone (HC) modify gene expression as well as stimulate human hematopoiesis in vivo and in vitro. The responses of blood-forming tissues, to these natural substances individually, are closely similar. However, clonogenic co-culture experiments, using normal human bone marrow cells, have revealed that the effects of Li and HC are not additive but rather mutually inhibitory. Studies of HL-60 cells in suspension indicate …
Authors
Knight SC; Harnish D; Scheid E; Koekebakker M; Barr RD
Journal
Leukemia Research, Vol. 13, No. 4, pp. 289–296
Publisher
Elsevier
Publication Date
January 1989
DOI
10.1016/0145-2126(89)90065-9
ISSN
0145-2126