Journal article
Omega‐3 supplementation alters mitochondrial membrane composition and respiration kinetics in human skeletal muscle
Abstract
Studies have shown increased incorporation of omega-3 fatty acids into whole skeletal muscle following supplementation, although little has been done to investigate the potential impact on the fatty acid composition of mitochondrial membranes and the functional consequences on mitochondrial bioenergetics. Therefore, we supplemented young healthy male subjects (n = 18) with fish oils [2 g eicosapentaenoic acid (EPA) and 1 g docosahexanoic acid …
Authors
Herbst EAF; Paglialunga S; Gerling C; Whitfield J; Mukai K; Chabowski A; Heigenhauser GJF; Spriet LL; Holloway GP
Journal
The Journal of Physiology, Vol. 592, No. 6, pp. 1341–1352
Publisher
Wiley
Publication Date
March 15, 2014
DOI
10.1113/jphysiol.2013.267336
ISSN
0022-3751
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
Adenine Nucleotide Translocator 1Adenine Nucleotide Translocator 2Adenosine DiphosphateCell RespirationDietary SupplementsDocosahexaenoic AcidsEicosapentaenoic AcidEnergy MetabolismFatty Acids, Omega-3HumansHydrogen PeroxideKineticsMaleMitochondria, MuscleMitochondrial MembranesOxidative StressPhospholipidsQuadriceps MuscleReactive Oxygen SpeciesYoung Adult