Jack Gauldie - McMaster Experts

Affiliations

Faculty of Health Sciences, McMaster University
Member, McMaster Immunology Research Centre (MIRC), Faculty of Health Sciences
Professor Emeritus, Pathology & Molecular Medicine, Faculty of Health Sciences

Scholarly Activity in McMaster Experts

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selected scholarly activity

chapters
- Growth Factors. 353-361. 2009
- Growth factors. 353-361. 2008
- Gene therapy for lung injury. 747-778. 2005
- Use of gene transfer to study lung: Cytokine biology. 171-191. 2002
conferences
- Mechanical stress-induced mast cell degranulation activates TGF-β1 signalling pathway in pulmonary fibrosis. Thorax. 455-465. 2019
- Loxl1 Null Mice Are Protected From Tgf-beta 1 Induced Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine. 2017
- Role Of Dendritic Cells In Pulmonary Fibrosis In Mice. American Journal of Respiratory and Critical Care Medicine. 2017
- Silica-Induced Pulmonary Fibrosis Occurs With The Activation Of Macrophage Polarization Through Marco And In A Tgf-beta 1-Independent Manner. American Journal of Respiratory and Critical Care Medicine. 2017
- The Fibrotic Extracellular Matrix (ecm) Induces Mast Cell Degranulation And Phenotypes Changing. American Journal of Respiratory and Critical Care Medicine. 2017
- Characterizing The Maturation Of Tgf-beta Induced Pulmonary Fibrotic Scar: Quantitation Of Extracellular Matrix Protein Synthesis, Remodeling And Crosslinking Rates. American Journal of Respiratory and Critical Care Medicine. 2016
- Macitentan Prevents Pulmonary Fibrosis Progression And Secondary Pulmonary Hypertension Induced By Tgf-beta 1 Overexpression In Rats. American Journal of Respiratory and Critical Care Medicine. 2016
- Fibroblast Growth Factor-1 Attenuates Tgf-beta 1-Induced Lung Fibrosis By Regulating Tgf-beta 1 Signaling. American Journal of Respiratory and Critical Care Medicine. 2015
- Mechanical Stress And Mast Cell Activation On Tgf-beta 1 Induced Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine. 2015
- Mmp19 Expression Induces Er Stress Independent Of Catalytic Domain Activity. American Journal of Respiratory and Critical Care Medicine. 2015
- Smad3 And Ttf-1 Complexes Regulate Surfactant Dysfunction During Overexpression Of Tgf-beta 1 And Contribute To Loss Of Epithelial Integrity In Vivo. American Journal of Respiratory and Critical Care Medicine. 2015
- Streptococcus Pneumoniae Triggers Progression Of Pulmonary Fibrosis Through Pneumolysin. American Journal of Respiratory and Critical Care Medicine. 2015
- Fibroblast Growth Factor-1 Attenuates Tgf beta 1-Induced Lung Fibrosis Through Inhibition Of Smad2 Phosphorylation. American Journal of Respiratory and Critical Care Medicine. 2014
- Identification Of A Novel Region Of The Itgb6 Promoter Responsible For Basal Repression Of Itgb6 Transcription And Therefore av beta 6 Expression. American Journal of Respiratory and Critical Care Medicine. 2014
- The Kinetics Of Crosslinking Enzymes And Ecm Components In Experimental Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine. 2014
- Transfer Of Active Tgf-beta 1 To The Mouse Lung: Early Effects On Lung Mechanics, Structure And Surfactant Function In Vivo. American Journal of Respiratory and Critical Care Medicine. 2014
- Interdependence of HIF1 alpha/TGF beta 1 activity in induction of pulmonary fibrosis. European Respiratory Journal. 2013
- Mechanisms regulating enhanced alpha v beta 6 expression in pulmonary fibrosis. European Respiratory Journal. 2013
- Mechanisms regulating enhanced alpha v beta 6 expression in pulmonary fibrosis. European Respiratory Journal. 2013
- Fibroblast Growth Factor-1 Ameliorates Tgf-beta 1-Induced Lung Dysfunction And Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine. 2013
- Modifying Fibrocyte Responses In Rat Bleomycin-Induced Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine. 2013
- Multiple Mechanisms Regulating Enhanced Expression Of alpha v beta 6 Integrins In Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine. 2013
- Overexpression Of Il-13ra2 In The Mouse Lung Inhibits Induction Of Fibrotic Markers In Bleomycin Induced Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine. 2013
- S69 Transcriptional Mechanisms Regulating Expression of the Avb6 Integrin in IPF. Thorax. A34.3-A35. 2012
- Overexpression of IL-13R alpha 2 Inhibits the Fibrotic Response. Irish Journal of Medical Science. S413-S413. 2012
- ETHANOL SENSITIZES PRIMARY MOUSE HEPATOCYTES FOR THE APOPTOTIC EFFECTS OF TRANSFORMING GROWTH FACTOR (TGF)-beta. Alcoholism: Clinical and Experimental Research. 36A-36A. 2012
- The fibrotic microenvironment: The permissive 'soil' switching disseminated dormant tumor cells to metastatic growth. International Journal of Molecular Medicine. S39-S39. 2012
- Experimental Lung Fibrosis and Pulmonary Hypertension Induces Cardiomyocyte Apoptosis and Right Ventricular Dysfunction. Circulation. 2011
- Adenoviral Gene Transfer Of Granulocyte/Macrophage Colony Stimulating Factor Enhances Pulmonary Host Defense And Survival From Pneumococcal Pneumonia In Mice. American Journal of Respiratory and Critical Care Medicine. 2011
- The effect of curcumin in transforming growth factor beta 1-induced rat lung fibrosis. The FASEB Journal. 2011
- Type I collagen enrichment at the metastatic site: The 'soil' triggering the transition from tumor dormancy to metastatic growth. Clinical and Experimental Metastasis. 174-174. 2011
- Latent TGF Activated By Mechanical Force Promotes Endogenous TGF Positive Feedback. American Journal of Respiratory and Critical Care Medicine. 2011
- Tissue Repair In Cystic Fibrosis Lung Disease. American Journal of Respiratory and Critical Care Medicine. 2011
- S125 Ly6Chi circulating monocytes direct alternatively activated, pro-fibrotic, lung macrophage regulation of pulmonary fibrosis. Thorax. A57-A57. 2010
- Transient Adenovirus-mediated Overexpression Of HIF-1± Induces Epithelial Injury In Rat Lungs. American Journal of Respiratory and Critical Care Medicine. 2010
- Gene Transfer Of Extracellular Superoxide Dismutase Ameliorates Pulmonary Fibrosis In Rats. American Journal of Respiratory and Critical Care Medicine. 2010
- Role Of MMP19 In Epithelial-Mesenchymal Transition And Fibrosis. American Journal of Respiratory and Critical Care Medicine. 2010
- VEGF receptor inhibition in experimental lung fibrosis results in severe angioproliferative pulmonary hypertension and increased fibrogenic activity. American Journal of Respiratory and Critical Care Medicine. 2010
- Effects of Bacterial Infection withPseudomonas aeruginosaon Experimental Pulmonary Fibrosis.. American Journal of Respiratory and Critical Care Medicine. 2009
- TGF-beta Antagonist Antibody 1D11 Blocks Experimental Progressive Pulmonary Fibrosis.. American Journal of Respiratory and Critical Care Medicine. 2009
- VEGF Overexpression during Fibrogenesis Reduces Endothelial Cell Apoptosis and Improves Pulmonary Hypertension.. American Journal of Respiratory and Critical Care Medicine. 2009
- BMP-Antagonist Gremlin Induces Fibroblastic Foci through EMT in the Rodent Lung. American Journal of Respiratory and Critical Care Medicine. 2009
- Mechanical Stimulation of Fibrotic Ex Vivo Lung Strips Activates Latent TGF beta. American Journal of Respiratory and Critical Care Medicine. 2009
- Pilot study assessing the utility of an adhesion array and high-sensitivity cytokine array as surrogate biomarkers in ovarian cancer. Clinical Biochemistry. 1271-1271. 2008
- Autologous dendritic cell vaccination of dogs with oral melanoma using human gp100 antigen. Journal of Veterinary Internal Medicine (JVIM). 772-772. 2008
- Inflammation and the Aging Process: Devil or Angel. Nutrition Reviews. 167-169. 2007
- TGF beta and Smad3 link matrix expression and progressive fibrosis. International Journal of Experimental Pathology. A81-A81. 2007
- Interferon-gamma induced chemokines synergize with pertussis toxin to promote T cell entry to the central nervous system. Scandinavian Journal of Immunology. 610-610. 2007
- Large-Scale Production of Autologous CD14+-Monocyte Derived Dendritic Cells Co-Electroporated with Amplified Total Tumour mRNA and Human CD40L mRNA in Patients with B-Cell Chronic Lymphocytic Leukemia.. Blood. 3720-3720. 2006
- Interferon-gamma induced chemokines and pertussis toxin synergize to promote T cell entry to the central nervous system. Journal of Neuroimmunology. 84-84. 2006
- 316. Production of Adenoviral Vectors in an Academic cGMP Facility. Molecular Therapy. S121-S121. 2006
- Inhibition of SMC proliferation and in-stent intimal hyperplasia by overexpression of p15, an INK4 cyclin-dependent kinase inhibitor. Circulation. U226-U226. 2005
- Intramural overexpression of monocyte chemoattractant protein-1 in mouse colon induces fibrosis via T-cell-depenclent mechanism. Gastroenterology. A213-A213. 2005
- Prophylactic and therapeutic application of an adenovirus vector expressing IL-12 against leishmaniasis in BALB/c mice. The FASEB Journal. A941-A941. 2005
- Gene transfer of bioactive IL-1b to the anterior chamber of the rodent eye induces a retinal phenotype similar to human proliferative vitreoretinopathy. Investigative Ophthalmology and Visual Science. 2005
- Gene transfer of bioactive TGF-b1 to the anterior chamber of the rodent eye induces anterior subcapsular cataracts and alterations to the trabecular meshwork. Investigative Ophthalmology and Visual Science. 2005
- Lens specific expression of TGF-b induces anterior subcapsular cataract formation in the absence of Smad3 signaling. Investigative Ophthalmology and Visual Science. 2005
- TGF-beta1 induces concomitant lung fibrosis, decreased GSH and ascorbate concentrations, and increased PAI-1 gene expression. Free Radical Biology and Medicine. S37-S37. 2005
- Selectins mediate TNF-alpha-dependent platelet adherence to the intact cerebral vasculature. Journal of Neuroimmunology. 67-67. 2004
- Induction of colonic fibrosis in mice by intramural gene transfer of monocyte chemoattractant protein-1. Gastroenterology. A419-A419. 2004
- Induction of specific immunity to B-CLL cells by in vitro stimulation using antigen pulsed autologous dendritic cells.. Blood. 439A-439A. 2003
- Isolation and identification of mammaglobin gene upstream region (25.4 kb) using helper-dependent adenoviral vectors. Molecular Therapy. S433-S433. 2003
- Adenoviral-vector-induced mucosal immunity against genital or rectal viral infection is enhanced by immunization in the rectal mucosa: Implications for mucosal vaccine design. The FASEB Journal. C86-C86. 2003
- Interaction between CD40 and CD40 ligand is required in the development of intestinal muscle contractility and host immunity during nematode infection. Gastroenterology. A337-A337. 2003
- MCP-1 gene transfer enhances intestinal muscle contractility during nematode infection. Gastroenterology. A346-A346. 2003
- Adenovirus mediated gene transfer of transforming growth factor beta 3 to the rat peritoneum leads to transient ultrafiltration dysfunction.. Journal of the American Society of Nephrology. 40A-40A. 2002
- Adenoviral-based gene delivery in the lower GI tract induces antigen-specific immune responses in the colonic mucosa. Gastroenterology. A271-A272. 2002
- Vbeta 8.2 TCR-centered regulation of experimental autoimmune encephalomyelitis is disrupted by co-administration with adenovirus vectors expressing either interleukin-4 or 10.. The FASEB Journal. A1058-A1058. 2002
- Hepatic leukocyte-endothelial cell interactions in a model of chronic IL-1 expression. The FASEB Journal. A123-A123. 2002
- Bone marrow derived dendritic cell vaccination of spontaneous canine melanoma using human gp100 antigen. Clinical and immunological findings.. Blood. 698A-698A. 2001
- Severe colonic injury induced by local over-expression of the IL-12 gene in the mouse. Gastroenterology. A115-A115. 2000
- Temporal separation of the dual effects of TGFB1 on epithelium: Early disruption in ion transport is followed by delayed increase in barrier function. Gastroenterology. A807-A807. 2000
- Effects of anti-inflammatory gene transfer on the survival of axotomized retinal ganglion cells in vivo: Comparison of IL-10, IL-4 and TGF-beta.. Investigative Ophthalmology and Visual Science. S189-S189. 2000
- Protection of axotomized retinal ganglion cells by in vivo adenovirus-mediated gene transfer of ciliary neurotrophic factor.. Investigative Ophthalmology and Visual Science. S189-S189. 2000
- Cytokine gene transfer to the liver and regulation of the acute-phase response. CYTOKINES AND CELL HOMEOSTASIS IN THE GASTROINTESTINAL TRACT. 229-240. 2000
- A novel role for combined anti-angiogenesis therapy and immunotherapy: Treatment of a murine breast cancer model using adenoviral gene therapy vectors expressing angiostatin and interleukin-12.. Blood. 620A-620A. 1999
- Adenoviral-based gene transfer in a murine model of chronic lymphocytic leukemia.. Blood. 314A-314A. 1999
- A single administration of the IL-4 or IL-12 gene along with self-peptides has long-lasting but opposite effects on autoantibody production in lupus mice.. Arthritis and Rheumatism. S362-S362. 1999
- Adenoviral gene transfer of active TGF-beta to the colonic epithelium causes fibrosis and strictures. Gastroenterology. A685-A685. 1999
- DIFFERENTIAL EFFECTS OF DENDRITIC CELLS OVEREXPRESSING MAMMALIAN IL-10 ON ORGAN ALLOGRAFT AND ANTI-TUMOR IMMUNITY. Transplantation. S248-S248. 1999
- Adenovirus-mediated decorin gene transfer prevents TGF-beta-induced inhibition of lung morphogenesis. The FASEB Journal. A354-A354. 1999
- Adenovirus-mediated decorin gene transfer prevents TGF-beta-induced inhibition of embryonic lung branching morphogenesis.. American Journal of Respiratory and Critical Care Medicine. A239-A239. 1999
- IL-10 gene transfer downregulates allograft tracheal transplant induced IL-2 gene expression. American Journal of Respiratory and Critical Care Medicine. A275-A275. 1999
- Mast cell hyperplasia and heterogeneity in a TGF-beta 1-induced model of pulmonary fibrosis.. American Journal of Respiratory and Critical Care Medicine. A402-A402. 1999
- Transforming Growth Factor-β Gene Transfer to the Lung Induces Myofibroblast Presence and Pulmonary Fibrosis. Current topics in pathology. 35-45. 1999
- Loss of CD34(+)/CD38(-) cells during ex vivo expansion of purified CD34(+) stem cells using adenoviral-based gene transfer of stem cell factor to bone marrow stromal cells.. Blood. 151A-151A. 1998
- Epithelium-specific adenoviral transfer of a dominant-negative mutant TGF-beta type II receptor stimulates embryonic lung branching morphogenesis in culture and potentiates EGF and PDGF-AA.. Developmental Biology. 205-205. 1998
- The facilitative role of epithelial barrier disruption in successful gene transfer to the colon. Gastroenterology. A1104-A1104. 1998
- Adenoviruses expressing cytokines can alter T cell differentiation and affect recovery against murine cutaneous leishmaniasis. The FASEB Journal. A572-A572. 1998
- Gene transfer using recombinant adenovirus vectors in murine lupus: Intrinsic immunogenicity and anti-self responses.. Journal of Investigative Medicine. 216A-216A. 1998
- Adenovirus-transduced dendritic cells prime both CD8 class I and CD4 class II-restricted CTL via CD4-dependent mechanism.. Journal of Leukocyte Biology. 99-99. 1998
- Modulation of dendritic cell function and effects on allograft survival by TGF beta or IL-10 gene transduction. Journal of Leukocyte Biology. 40-40. 1998
- Adenoviral-based gene transfer of two forms of stem cell factor to human bone marrow stromal cells.. Blood. 4609-4609. 1997
- Intramarrow administration of an adenoviral vector expressing canine GM-CSF to alleviate neutropenia in dogs treated with chemotherapy.. Blood. 1062-1062. 1997
- Isolation and characterization of cultured human dendritic cells: A potential target for adenoviral-based gene transfer of tumour peptides.. Blood. 4636-4636. 1997
- Amelioration of experimental colitis by interleukin-10 gene transfer. Gut. A69-A69. 1997
- Cytokine gene transfer modifies inflammation and regulates cytokine and chemokine production in murine arthritis.. Arthritis and Rheumatism. 1137-1137. 1997
- Interleukin-12 and B7-1 costimulatory molecule expressed by an adenovirus vector act synergistically to facilitate tumor regression. Cancer Gene Therapy. 317-318. 1997
- Renal effects of intramuscular TGF-beta 1 adenovirus gene therapy in tolerant rats.. Journal of the American Society of Nephrology. A2387-A2387. 1997
- Tumour immunotherapy using an adenoviral vector expressing a membrane bound mutant of murine TNF. Cancer Gene Therapy. 300-301. 1997
- Adenovirus-Mediated Gene Transfer of the Proteoglycan Biglycan Induces Fibroblastic Responses in the Lung. Chest. 137S-137S. 1997
- In Vivo Adenovirus-Mediated Expression of Human Pre-Elafin, a Potent Neutrophil Elastase Inhibitor. Chest. 128S-129S. 1997
- Amelioration of experimental colitis by IL-4 gene transfer.. Gastroenterology. A997-A997. 1997
- Gene transfer to monocytes & macrophages: Potential target for gene therapy of intestinal inflammation.. Gastroenterology. A927-A927. 1997
- Interleukin-10 gene therapy prevents the occurrence but doesn't reverse experimental colitis.. Gastroenterology. A927-A927. 1997
- Transgene-induced production of IL-4 alters the development and collagen expression of Th1 type pulmonary granulomas.. The FASEB Journal. 1328-1328. 1997
- Intradermal GM-CSF gene transfer in rat induces skin pathologies similar to chronic atopic dermatitis.. Journal of Allergy and Clinical Immunology. 1078-1078. 1997
- Adenovirus‐Vector‐Mediated Cytokine Gene Transfer to Lung Tissue^a. Annals of the New York Academy of Sciences. 235-244. 1996
- Transient IL-10 and IL-12 overexpression modifies disease in murine collagen induced arthritis.. Arthritis and Rheumatism. 307-307. 1996
- A novel component of the neuro-immune axis in the gut: Neural modulation of cytokine production by intestinal smooth muscle.. Gastroenterology. A1128-A1128. 1996
- Interleukin-4 gene transfer to the intestine causes inflammation and muscle dysfunction in the mouse. Gastroenterology. A1034-A1034. 1996
- Intra-marrow administration of adenoviral vectors for localized cytokine delivery.. Blood. 1636-1636. 1995
- Adenovirus Vectors for Cytokine Gene Expression. Annals of the New York Academy of Sciences. 282-293. 1995
- ADENOVIRUS VECTOR CYTOKINE GENE-TRANSFER TO LUNG-TISSUE. Journal of Cellular Biochemistry. 377-377. 1995
- EFFECTIVE CYTOKINE GENE-TRANSFER TO BONE-MARROW STROMAL CELLS USING ADENOVIRAL VECTORS. Journal of Cellular Biochemistry. 406-406. 1995
- GENE-THERAPY OF CANCER USING RECOMBINANT ADENOVIRUS VECTORS EXPRESSING CYTOKINES. Journal of Cellular Biochemistry. 417-417. 1995
- INTRATUMOR INJECTION OF A REC-ADENOVIRUS EXPRESSING MURINE IL-6 ATTENUATES TUMOR-GROWTH IN A TRANSGENIC BREAST-CARCINOMA MODEL. Journal of Cellular Biochemistry. 418-418. 1995
- ONCOSTATIN-M INHIBITS NEUTROPHIL INFLUX IN LPS-INDUCED ACUTE LUNG INFLAMMATION IN SPRAGUE-DAWLEY RATS. The FASEB Journal. A492-A492. 1995
- Cytokine regulation of hepatic acute phase protein expression. CYTOKINES AND THE LIVER. 164-171. 1995
- EFFECTIVE CYTOKINE GENE-TRANSFER IN HUMAN LONG-TERM BONE-MARROW CULTURED-CELLS USING ADENOVIRAL VECTORS. Blood. A740-A740. 1994
- STEROID INHIBITION OF CYTOKINE-MEDIATED VASODILATION AFTER WARM HEART-SURGERY. Circulation. 202-202. 1994
- EXPRESSION AND PURIFICATION OF THE SOLUBLE FORM OF THE INTERLEUKIN-6 RECEPTOR USING 2 DIFFERENT EXPRESSION SYSTEMS - ESCHERICHIA-COLI AND BACULOVIRUS. The FASEB Journal. A139-A139. 1994
- RECOMBINANT ADENOVIRUS-MESSENGER RANTES GENE-TRANSFER INTO B16 MOUSE MELANOMA-CELLS REDUCES TUMORIGENICITY IN-VIVO. The FASEB Journal. A201-A201. 1994
- GENE-THERAPY OF CANCER USING CYTOKINE EXPRESSING RECOMBINANT ADENOVIRUS VECTORS. Journal of Cellular Biochemistry. 113-113. 1994
- An overview of the cellular changes in pulmonary hypertension. European Respiratory Review. 564-568. 1993
- Attenuation of pulmonary vascular remodelling by natriuretic peptides. European Respiratory Review. 576-580. 1993
- Cyclic mechanical load and growth factors stimulate endothelial and smooth muscle cell DNA synthesis. European Respiratory Review. 618-622. 1993
- Elastase activity and the pathophysiology of pulmonary hypertension. European Respiratory Review. 591-597. 1993
- Elastin metabolism in the vessel wall during pulmonary hypertension. European Respiratory Review. 581-590. 1993
- Endothelial cell derived growth factors in pulmonary vascular hypertension. European Respiratory Review. 638-643. 1993
- Role of interstitial fibroblasts and intermediate cells in microvascular wall remodelling in pulmonary hypertension. European Respiratory Review. 569-575. 1993
- The role of mechanical force in the regulation of fibroblast function: Implications for enhanced collagen deposition during pulmonary vascular remodelling. European Respiratory Review. 613-617. 1993
- INTERLEUKIN-6 INDUCES HEPATIC VITRONECTIN RNA EXPRESSION IN RATS - A POTENTIAL MECHANISM FOR POSTOPERATIVE ELEVATION OF PLASMA VITRONECTIN IN HUMANS. Thrombosis and Haemostasis. 1026-1026. 1993
- ANCHORAGE-INDEPENDENT GROWTH OF FIBROBLAST COLONIES FROM LINES ESTABLISHED FROM HUMAN IDIOPATHIC PULMONARY FIBROTIC TISSUE. American Review of Respiratory Disease. A158-A158. 1993
- CYTOKINE DETECTION IN THE SPUTUM OF SMOKERS WITH MINIMAL AIR-FLOW LIMITATION [CAL]. American Review of Respiratory Disease. A865-A865. 1993
- DETECTION OF TUMOR-NECROSIS-FACTOR-ALPHA (TNF-ALPHA) AND MACROPHAGE INFLAMMATORY PEPTIDE-2 (MIP-2) IN THE LUNG OF RATS EXPOSED TO A SINGLE INTRATRACHEAL INSTILLATION OF LIPOPOLYSACCHARIDE (LPS). American Review of Respiratory Disease. A730-A730. 1993
- PLATELET-DERIVED GROWTH FACTOR-B (PDGF-B) GENE-EXPRESSION BY EOSINOPHILS IN CHRONICALLY INFLAMED UPPER AIRWAY TISSUES. American Review of Respiratory Disease. A822-A822. 1993
- SEQUENTIAL EXPRESSION OF CYTOKINES IN LUNG TISSUES FROM RATS EXPOSED TO CADMIUM CHLORIDE (CDCL2). American Review of Respiratory Disease. A734-A734. 1993
- THE PRECURSOR OF ELAFIN (PRE-ELAFIN) - GENE STRUCTURE AND REGULATION. American Review of Respiratory Disease. A678-A678. 1993
- EFFECTOR FUNCTION OF TISSUE STRUCTURAL CELLS IN INFLAMMATION. ASTHMA. 211-225. 1993
- SERUM INTERLEUKIN-6 LEVELS IN CYSTIC-FIBROSIS PATIENTS AND HEALTHY CONTROLS AT REST AND AFTER HIGH-INTENSITY EXERCISE. Journal of Allergy and Clinical Immunology. 209-209. 1993
- THE PATHOLOGY OF PULMONARY-HYPERTENSION. European Respiratory Review. 555-558. 1993
- CONSTRUCTION AND INVIVO EFFECTS OF A RECOMBINANT HUMAN ADENOVIRUS TYPE-5 EXPRESSING THE MURINE INTERLEUKIN-6 CDNA ON REPLICATION. The FASEB Journal. A1781-A1781. 1992
- IL-6 AND IL-6 RECEPTOR (IL-6R) EXPRESSION AND MODULATION DURING ACUTE-INFLAMMATION IN THE RAT. The FASEB Journal. A1896-A1896. 1992
- REGULATION OF TIMP EXPRESSION IN SYNOVIAL FIBROBLASTS BY PGE2 AND CYTOKINES. The FASEB Journal. A941-A941. 1992
- ACUTE-PHASE RESPONSES - GENERAL DISCUSSION. POLYFUNCTIONAL CYTOKINES : IL-6 AND LIF. 156-159. 1992
- CYTOKINES AND BINDING-PROTEINS IN THE CIRCULATION - GENERAL DISCUSSION. POLYFUNCTIONAL CYTOKINES : IL-6 AND LIF. 260-264. 1992
- HEMATOPOIETIC GROWTH-FACTOR NETWORKING IN THE CYCLIC HEMATOPOIETIC DOG. Experimental Hematology. 117-117. 1992
- INTERLEUKIN-6, LEUKEMIA INHIBITORY FACTOR AND GRANULOCYTE COLONY-STIMULATING FACTOR - GENERAL DISCUSSION. POLYFUNCTIONAL CYTOKINES : IL-6 AND LIF. 201-203. 1992
- Molecular biology and immunology of interleukin-6: Discussion. Research in Immunology. 779-783. 1992
- THE EFFECTS OF LEUKEMIA INHIBITORY FACTOR AND INTERLEUKIN-6 ON VASCULAR FUNCTION. POLYFUNCTIONAL CYTOKINES : IL-6 AND LIF. 203-204. 1992
- LIF PRODUCTION BY RAT MAST-CELL LINES. The FASEB Journal. A1084-A1084. 1991
- CYTOKINE CONTROL OF ACUTE PHASE PROTEIN EXPRESSION. CYTOKINES AND INFLAMMATION. 29-50. 1991
- THE LATE ASTHMATIC RESPONSE (LAR) AND THE TISSUE DRIVEN RESPONSE (TDR). ADVANCES IN ASTHMOLOGY 1990. 247-250. 1991
- IL-6 PRODUCTION BY RAT MAST-CELL LINES. ADVANCES IN MUCOSAL IMMUNOLOGY. 148-149. 1990
- MODULATION OF UPPER AIRWAY INFLAMMATION BY FIBROBLAST AND EPITHELIAL-CELL DERIVED CYTOKINES. Clinical Research. A239-A239. 1989
- PDGF EXPRESSION IN HUMAN NEONATAL PULMONARY FIBROBLASTS FOLLOWING HYPEROXIA. Pediatric Research. A317-A317. 1989
- EPITHELIAL-CELLS DERIVED FROM NASAL POLYPS AND INFERIOR TURBINATE TISSUES PRODUCE NEUTROPHILIC AND MONOCYTIC DIFFERENTIATING ACTIVITY. Journal of Allergy and Clinical Immunology. 299-299. 1989
- FIBROBLASTS DERIVED FROM HUMAN NASAL TISSUES PRODUCE NEUTROPHILIC AND BASOPHILIC DIFFERENTIATING FACTORS INCLUDING GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR (GM-CSF). Journal of Allergy and Clinical Immunology. 300-300. 1989
- INTERLEUKIN 6 IN THE INFLAMMATORY RESPONSE. THERAPEUTIC APPROACHES TO INFLAMMATORY DISEASES. 38-46. 1989
- MODULATION OF PGE2 RELEASE AND PROCOLLAGEN MESSENGER-RNA EXPRESSION IN HUMAN-LUNG FIBROBLASTS BY PERIPHERAL-BLOOD MONOCYTE SUPERNATANTS. Australian and New Zealand Journal of Medicine. 527-527. 1988
- EFFECTS OF DEXAMETHASONE ON INHIBITORY EFFECTS OF TRANSFORMING GROWTH FACTOR-BETA-1 AND FACTOR-BETA-2 IN NORMAL AND NEOPLASTIC RAT HEPATOCYTES. Proceedings / Annual Meeting of the American Association for Cancer Research [and] Annual Meeting of the American Society of Clinical Oncology. American Association for Cancer Research. Meeting. 57-57. 1988
- INTERFERON-BETA-2 IS IDENTICAL TO HSF AND REGULATES THE FULL ACUTE PHASE PROTEIN RESPONSE IN LIVER-CELLS. Journal of Leukocyte Biology. 554-554. 1987
- COMPARISON OF INTERLEUKIN-1 AND TUMOR-NECROSIS-FACTOR AS INDUCERS OF THE ACUTE PHASE RESPONSE OF CULTURED-HEPATOCYTES AND HEPATOMA-CELLS. Immunobiology. 65-66. 1987
- MACROPHAGE DERIVED IL-1 AND HEPATOCYTE STIMULATING FACTOR (HSF) ARE DISTINCT ENTITIES THAT INDUCE ACUTE PHASE PROTEIN-SYNTHESIS. Journal of Leukocyte Biology. 274-274. 1986
- ALVEOLAR MACROPHAGE ACTIVATION IN BRONCHOPULMONARY DYSPLASIA. American Review of Respiratory Disease. A207-A207. 1986
- CHARACTERISTICS OF HUMAN ADULT LUNG FIBROBLAST STRAINS AND CLONALLY-DERIVED LINES FROM NORMAL AND FIBROTIC TISSUE. American Review of Respiratory Disease. A36-A36. 1986
- HUMAN-LUNG FIBROBLASTS EXPRESS AN H2 HISTAMINE-RECEPTOR WHICH CAN MODULATE INVITRO PROLIFERATION. American Review of Respiratory Disease. A35-A35. 1986
- PURIFICATION OF HEPATOCYTE STIMULATING FACTOR FROM RAT ALVEOLAR MACROPHAGES. The FASEB Journal. 1187-1187. 1985
- PURIFIED HUMAN MONOCYTE IL-1 STIMULATES HEPATOCYTE SECRETION OF MULTIPLE ACUTE PHASE PROTEINS INVITRO. Journal of Leukocyte Biology. 706-706. 1985
- THE ACUTE PHASE RESPONSE ASSOCIATED WITH GI INFLAMMATION DUE TO ENTERIC PARASITES. The FASEB Journal. 1707-1707. 1985
- ALVEOLAR MACROPHAGE FACTORS MODULATE THE INVITRO RESPONSE OF LYMPHOCYTES, FIBROBLASTS AND HEPATOCYTES. Journal of Leukocyte Biology. 411-411. 1984
- IMMUNOREGULATION BY DIOXIN AND RELATED HALOAROMATIC HYDROCARBONS. Journal of Leukocyte Biology. 392-392. 1984
- SERUM IGG IS THE MAJOR INVIVO DETERMINANT OF CLEARANCE OF IGG-SENSITIZED ERYTHROCYTES. Clinical Research. A350-A350. 1984
- ALTERATIONS IN NUMBERS AND HELMINTHOTOXICITY OF RAT BRONCHO-ALVEOLAR LEUKOCYTES DURING NIPPOSTRONGYLUS-BRASILIENSIS INFECTION. The FASEB Journal. 1247-1247. 1983
- ALVEOLAR MACROPHAGE RELEASES IL1 AFTER ACTIVATION INVIVO BY INFECTION. The FASEB Journal. 1025-1025. 1983
- IMMUNOGLOBULIN AND COMPLEMENT RECEPTORS ON NORMAL AND ACTIVATED ALVEOLAR MACROPHAGE. The FASEB Journal. 955-955. 1983
- ANTI-HB PORTLAND ANTIBODIES - A SENSITIVE PROBE FOR HUMAN-EMBRYONIC HEMOGLOBIN. Clinical Research. A313-A313. 1982
- MONOCLONAL-ANTIBODIES TO HUMAN FERRITIN WITH DIRECT PRECIPITATING ACTIVITY. The FASEB Journal. 598-598. 1982
- PULMONARY-FUNCTION ABNORMALITIES IN PATIENTS WITH INFLAMMATORY BOWEL-DISEASE. Gut. A448-A449. 1982
- SYNTHESIS OF ALPHA-1 PROTEASE INHIBITOR BY NORMAL AND ACTIVATED MURINE ALVEOLAR MACROPHAGES. The FASEB Journal. 688-688. 1982
- THE MECHANISM OF MALARIA-INDUCED THROMBOCYTOPENIA. Clinical Research. A320-A320. 1982
- THE PRETREATMENT IDENTIFICATION OF THOSE PATIENTS WITH IDIOPATHIC THROMBOCYTOPENIC PURPURA WHO RESPOND TO PLASMAPHERESIS. Clinical Research. A320-A320. 1982
- 786 IMMUNO-IDENTIFICATION OF HUMAN FETAL FIBRINOGEN. Pediatric Research. 573-573. 1981
- SELECTIVE SUPPRESSION OF CYTO-TOXIC T-CELL (CTL) GENERATION BY HALOGENATED AROMATIC-HYDROCARBONS. The FASEB Journal. 1096-1096. 1981
- THE ACUTE PHASE RESPONSE IN THE EARLY STAGE OF PARASITE INFECTION. The FASEB Journal. 1072-1072. 1981
- ALTERED DISTRIBUTION OF ALPHA-1-ANTITRYPSIN CONTAINING CELLS IN MOUSE-LIVER AND PANCREAS DURING ACUTE INFLAMMATORY RESPONSE. The FASEB Journal. 645-645. 1980
- PLASMAPHERESIS IS EFFECTIVE IN THROMBOTIC THROMBOCYTOPENIA PURPURA (TTP) BY ALTERING THE BINDING CHARACTERISTICS OF IMMUNE-COMPLEXES. Circulation. 105-105. 1980
- THE MAJORITY OF PLATELET ASSOCIATED IGG (PAIGG) IS IN THE INTERIOR OF PLATELETS AND NOT MEASURABLE USING STANDARD ASSAYS. Transfusion. 625-626. 1980
- BASOPHIL STIMULATING FACTOR FROM GUINEA-PIG SPLENIC LYMPHOCYTES-T. Clinical Research. A470-A470. 1979
- ANTIBODY INDUCED ALPHA-1 ANTI-TRYPSIN DEFICIENCY IN MOUSE. The FASEB Journal. 1487-1487. 1978
- COMPARISON OF METHODS FOR MEASURING IMMUNOGLOBULINS AND C-3. Clinical Biochemistry. P8-P8. 1978
- HUMAN PANCREATIC POLYPEPTIDE (HPP) PLASMA CONCENTRATIONS IN FASTING HUMAN INFANTS AND ADULTS. Diabetologia. 276-277. 1978
- IMMUNOCYTOCHEMICAL IDENTIFICATION OF ADULT AND EMBRYONIC HEMOGLOBINS IN YOLK-SAC DERIVED ERYTHROCYTES DURING NORMAL MOUSE FETAL DEVELOPMENT. Clinical Research. A342-A342. 1978
- MOTILIN AND HUMAN PANCREATIC POLYPEPTIDE (HPP) PLASMA CONCENTRATIONS IN 196 FASTING SUBJECTS. Scandinavian Journal of Gastroenterology. 187-187. 1978
- THROMBOCYTOPENIA INDUCED BY BUSULFAN AND ANTIPLATELET SERUM INHIBITS AORTIC LESIONS CAUSED BY INJURY. Circulation. 121-121. 1977
- EFFECT OF THROMBOCYTOPENIA ON ARTERIOSCLEROTIC PLAQUE-FORMATION. The FASEB Journal. 207-207. 1976
journal articles
- Role of matrix metalloprotease-2 and MMP-9 in experimental lung fibrosis in mice. Respiratory Research. 23:180. 2022
- B Cells Are Not Involved in the Regulation of Adenoviral TGF-β1– or Bleomycin-Induced Lung Fibrosis in Mice. Journal of Immunology. 208:1259-1271. 2022
- Role of the COX2-PGE₂ axis in S. pneumoniae-induced exacerbation of experimental fibrosis. American Journal of Physiology - Lung Cellular and Molecular Physiology. 320:L377-L392. 2021
- The importance of interventional timing in the bleomycin model of pulmonary fibrosis. European Respiratory Journal. 55:1901105-1901105. 2020
- Regulatory T Cells Limit Pneumococcus-Induced Exacerbation of Lung Fibrosis in Mice. Journal of Immunology. 204:2429-2438. 2020
- FPR-1 is an important regulator of neutrophil recruitment and a tissue-specific driver of pulmonary fibrosis. JCI insight. 5:125937. 2020
- Fibrocytes and fibroblasts—Where are we now. International Journal of Biochemistry and Cell Biology. 116:105595-105595. 2019
- The FMS-like tyrosine kinase-3 ligand/lung dendritic cell axis contributes to regulation of pulmonary fibrosis. Thorax. 74:947-957. 2019
- Surfactant dysfunction and alveolar collapse are linked with fibrotic septal wall remodeling in the TGF-β1-induced mouse model of pulmonary fibrosis. Laboratory Investigation. 99:830-852. 2019
- Macitentan reduces progression of TGF-β1-induced pulmonary fibrosis and pulmonary hypertension. European Respiratory Journal. 52:1701857-1701857. 2018
- Nanoscale dysregulation of collagen structure-function disrupts mechano-homeostasis and mediates pulmonary fibrosis. eLife. 7:e36354. 2018
- Lysyl Oxidase–Like 1 Protein Deficiency Protects Mice from Adenoviral Transforming Growth Factor-β1–induced Pulmonary Fibrosis. American Journal of Respiratory Cell and Molecular Biology. 58:461-470. 2018
- Adenoviral vector-mediated GM-CSF gene transfer improves anti-mycobacterial immunity in mice – role of regulatory T cells. Immunobiology. 223:331-341. 2018
- Antacid therapy in idiopathic pulmonary fibrosis: more questions than answers?. The Lancet Respiratory Medicine. 5:591-598. 2017
- Fibroblast growth factor-1 attenuates TGF-β1-induced lung fibrosis. Journal of Pathology. 240:197-210. 2016
- Stretch-induced Activation of Transforming Growth Factor-β₁ in Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine. 194:84-96. 2016
- Surfactant dysfunction during overexpression of TGF-β1 precedes profibrotic lung remodeling in vivo. American Journal of Physiology - Lung Cellular and Molecular Physiology. 310:L1260-L1271. 2016
- Editorial: Extracellular Matrix: The Common Thread of Disease Progression in Fibrosis?. Arthritis & Rheumatology. 68:1053-1056. 2016
- Mucking around in the Genome: MUC5B in Idiopathic Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine. 193:355-357. 2016
- Amplification of TGFβ Induced ITGB6 Gene Transcription May Promote Pulmonary Fibrosis. PLoS ONE. 11:e0158047-e0158047. 2016
- Novel chimpanzee adenovirus-vectored respiratory mucosal tuberculosis vaccine: overcoming local anti-human adenovirus immunity for potent TB protection. Mucosal Immunology. 8:1373-1387. 2015
- Dissecting fibrosis: therapeutic insights from the small-molecule toolbox. Nature Reviews Drug Discovery. 14:693-720. 2015
- A novel profibrotic mechanism mediated by TGFβ‐stimulated collagen prolyl hydroxylase expression in fibrotic lung mesenchymal cells. Journal of Pathology. 236:384-394. 2015
- Streptococcus pneumoniae triggers progression of pulmonary fibrosis through pneumolysin. Thorax. 70:636-646. 2015
- Modulation of pulmonary fibrosis by IL-13Rα2. American Journal of Physiology - Lung Cellular and Molecular Physiology. 308:L710-L718. 2015
- Matrix Metalloproteinase-19 Promotes Metastatic BehaviorIn Vitroand Is Associated with Increased Mortality in Non–Small Cell Lung Cancer. American Journal of Respiratory and Critical Care Medicine. 190:780-790. 2014
- The small heat‐shock protein αB‐crystallin is essential for the nuclear localization of Smad4: impact on pulmonary fibrosis. Journal of Pathology. 232:458-472. 2014
- Type 1 interferon gene transfer enhances host defense against pulmonary Streptococcus pneumoniae infection via activating innate leukocytes. Molecular Therapy - Methods and Clinical Development. 1:5-5. 2014
- A Human Type 5 Adenovirus–Based Tuberculosis Vaccine Induces Robust T Cell Responses in Humans Despite Preexisting Anti-Adenovirus Immunity. Science Translational Medicine. 5:205ra134. 2013
- New treatment and markers of prognosis for idiopathic pulmonary fibrosis: lessons learned from translational research. Expert Review of Respiratory Medicine. 7:465-478. 2013
- Extracellular matrix microenvironment contributes actively to pulmonary fibrosis. Current Opinion in Pulmonary Medicine. 19:446-452. 2013
- Inflammation Induced by MMP-9 Enhances Tumor Regression of Experimental Breast Cancer. Journal of Immunology. 190:4420-4430. 2013
- Inhibition of HSP27 blocks fibrosis development and EMT features by promoting Snail degradation. The FASEB Journal. 27:1549-1560. 2013
- Adenoviral-Mediated Gene Transfer into Bone Marrow: An Effective Surgical Technique in Rat. European Surgical Research. 50:282-291. 2013
- Fibrocytes in chronic lung disease – Facts and controversies. Pulmonary Pharmacology and Therapeutics. 25:263-267. 2012
- Molecular mechanisms of MMP9 overexpression and its role in emphysema pathogenesis of Smad3-deficient mice. American Journal of Physiology - Lung Cellular and Molecular Physiology. 303:L89-L96. 2012
- Regulation of Transforming Growth Factor-β1–driven Lung Fibrosis by Galectin-3. American Journal of Respiratory and Critical Care Medicine. 185:537-546. 2012
- Negative Regulation of Lung Inflammation and Immunopathology by TNF-α during Acute Influenza Infection. American Journal of Pathology. 179:2963-2976. 2011
- Local Delivery of GM-CSF Protects Mice from Lethal Pneumococcal Pneumonia. Journal of Immunology. 187:5346-5356. 2011
- Cigarette smoke exposure aggravates air space enlargement and alveolar cell apoptosis inSmad3knockout mice. American Journal of Physiology - Lung Cellular and Molecular Physiology. 301:L391-L401. 2011
- Induction of specific human cytotoxic T cells using dendritic cells transduced with an adenovector encoding rat epidermal growth factor receptor 2. International Journal of Oncology. 39:907-913. 2011
- Matrix Metalloproteinase 3 Is a Mediator of Pulmonary Fibrosis. American Journal of Pathology. 179:1733-1745. 2011
- Idiopathic Pulmonary Fibrosis: The Matrix Is the Message. American Journal of Respiratory and Critical Care Medicine. 184:627-629. 2011
- Ly6C^hiMonocytes Direct Alternatively Activated Profibrotic Macrophage Regulation of Lung Fibrosis. American Journal of Respiratory and Critical Care Medicine. 184:569-581. 2011
- Oxidative stress contributes to the induction and persistence of TGF-β1 induced pulmonary fibrosis. International Journal of Biochemistry and Cell Biology. 43:1122-1133. 2011
- Mouse and human lung fibroblasts regulate dendritic cell trafficking, airway inflammation, and fibrosis through integrin αvβ8–mediated activation of TGF-β. Journal of Clinical Investigation. 121:2863-2875. 2011
- Pulmonary Hypertension and Idiopathic Pulmonary Fibrosis. American Journal of Respiratory Cell and Molecular Biology. 45:1-15. 2011
- Transient Overexpression of Gremlin Results in Epithelial Activation and Reversible Fibrosis in Rat Lungs. American Journal of Respiratory Cell and Molecular Biology. 44:870-878. 2011
- Inhibition of intimal hyperplasia after stenting by over-expression of p15: A member of the INK4 family of cyclin-dependent kinase inhibitors. Journal of Molecular and Cellular Cardiology. 50:417-425. 2011
- Let It Be. American Journal of Respiratory and Critical Care Medicine. 183:1-2. 2011
- Micro-computed tomography of pulmonary fibrosis in mice induced by adenoviral gene transfer of biologically active transforming growth factor-β1. Respiratory Research. 11:181. 2010
- Treatment combining RU486 and Ad5IL-12 vector attenuates the growth of experimentally formed prostate tumors and induces changes in the sentinel lymph nodes of mice. Journal of Translational Medicine. 8:98. 2010
- Transforming Growth Factor-β: Activation by Neuraminidase and Role in Highly Pathogenic H5N1 Influenza Pathogenesis. PLoS Pathogens. 6:e1001136-e1001136. 2010
- Overexpression of transforming growth factor- 1 in fetal monkey lung results in prenatal pulmonary fibrosis. European Respiratory Journal. 36:907-914. 2010
- Have advanced research technologies made real impact on respiratory medicine?. Respirology. 15:876-880. 2010
- Metastatic Growth from Dormant Cells Induced by a Col-I–Enriched Fibrotic Environment. Cancer Research. 70:5706-5716. 2010
- Effects of budesonide and formoterol on allergen-induced airway responses, inflammation, and airway remodeling in asthma. Journal of Allergy and Clinical Immunology. 125:349-356.e13. 2010
- Ocular Gene Transfer of Active TGF-β Induces Changes in Anterior Segment Morphology and Elevated IOP in Rats. Investigative Ophthalmology and Visual Science. 51:308-308. 2010
- Identification of Fibrocytes in Peripheral Blood. American Journal of Respiratory and Critical Care Medicine. 180:1279-1280. 2009
- Influence of the Tissue Microenvironment on Toll-Like Receptor Expression by CD11c⁺Antigen-Presenting Cells Isolated from Mucosal Tissues. Clinical and Vaccine Immunology. 16:1615-1623. 2009
- Immunization With a Bivalent Adenovirus-vectored Tuberculosis Vaccine Provides Markedly Improved Protection Over Its Monovalent Counterpart Against Pulmonary Tuberculosis. Molecular Therapy. 17:1093-1100. 2009
- VEGF ameliorates pulmonary hypertension through inhibition of endothelial apoptosis in experimental lung fibrosis in rats. Journal of Clinical Investigation. 119:1298-1311. 2009
- Circulating Fibrocytes Are an Indicator of Poor Prognosis in Idiopathic Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine. 179:588-594. 2009
- Comparison between conventional and "clinical" assessment of experimental lung fibrosis. Journal of Translational Medicine. 6:16. 2008
- Severe acute respiratory syndrome vaccine efficacy in ferrets: whole killed virus and adenovirus-vectored vaccines. Journal of General Virology. 89:2136-2146. 2008
- Mucosally Delivered Dendritic Cells Activate T Cells Independently of IL-12 and Endogenous APCs. Journal of Immunology. 181:2356-2367. 2008
- TGF- receptor II in epithelia versus mesenchyme plays distinct roles in the developing lung. European Respiratory Journal. 32:285-295. 2008
- Targeting fibrosis in respiratory lung disease. Drug Discovery Today: Therapeutic Strategies. 5:97-100. 2008
- The use of small animal imaging in respiratory disease drug discovery. Drug Discovery Today: Therapeutic Strategies. 5:81-85. 2008
- Cytokine elevations in acute coronary syndrome and ovarian cancer: A mechanism for the up-regulation of the acute phase proteins in these different disease etiologies. Clinical Biochemistry. 41:607-610. 2008
- Gene Transfer of Matrix Metalloproteinase-9 Induces Tumor Regression of Breast CancerIn vivo. Cancer Research. 68:3405-3412. 2008
- Transforming Growth Factor-β Regulates House Dust Mite–induced Allergic Airway Inflammation but Not Airway Remodeling. American Journal of Respiratory and Critical Care Medicine. 177:593-603. 2008
- Animal models of pulmonary fibrosis: how far from effective reality?. American Journal of Physiology - Lung Cellular and Molecular Physiology. 294:L151-L151. 2008
- Enhanced Antitumor Immunity Elicited by Dendritic Cell Vaccines Is a Result of Their Ability to Engage Both CTL and IFNγ-producing NK Cells. Molecular Therapy. 16:411-418. 2008
- Enhanced antitumor immunity elicited by dendritic cell vaccines is a result of their ability to engage both CTL and IFN gamma-producing NK cells.. Molecular Therapy. 16:411-418. 2008
- Immunization with adenovirus at the large intestinal mucosa as an effective vaccination strategy against sexually transmitted viral infection. Mucosal Immunology. 1:78-88. 2008
- Progressive pulmonary fibrosis is mediated by TGF-β isoform 1 but not TGF-β3. International Journal of Biochemistry and Cell Biology. 40:484-495. 2008
- The bleomycin animal model: A useful tool to investigate treatment options for idiopathic pulmonary fibrosis?. International Journal of Biochemistry and Cell Biology. 40:362-382. 2008
- Inflammation and the Aging Process: Devil or Angel. Nutrition Reviews. 65:S167-S169. 2007
- Three-dimensional computed tomography imaging in an animal model of emphysema. European Respiratory Journal. 30:1082-1089. 2007
- TGF-β1 Induces Progressive Pleural Scarring and Subpleural Fibrosis. Journal of Immunology. 179:6043-6051. 2007
- Antigen Presentation by Exosomes Released from Peptide-Pulsed Dendritic Cells Is not Suppressed by the Presence of Active CTL. Journal of Immunology. 179:5024-5032. 2007
- Critical Negative Regulation of Type 1 T Cell Immunity and Immunopathology by Signaling Adaptor DAP12 during Intracellular Infection. Journal of Immunology. 179:4015-4026. 2007
- Critical negative regulation of immunopathology by signaling intracellular infection. Journal of Immunology. 179:4015-4026. 2007
- TGF-β, Smad3 and the process of progressive fibrosis. Biochemical Society Transactions. 35:661-664. 2007
- Eosinophilia is induced in the colon of Th2-sensitized mice upon exposure to locally expressed antigen. American Journal of Physiology - Gastrointestinal and Liver Physiology. 293:G383-G390. 2007
- Dendritic Cells Derived from Murine Colonic Mucosa Have Unique Functional and Phenotypic Characteristics. Journal of Immunology. 178:7984-7993. 2007
- IFN-γ-Induced Chemokines Synergize with Pertussis Toxin to Promote T Cell Entry to the Central Nervous System. Journal of Immunology. 178:8175-8182. 2007
- TGFβ and Smad3 link inflammation to progressive fibrosis. International Congress Series. 1302:103-113. 2007
- Adenoviral gene transfer of bioactive TGFbeta1 to the rodent eye as a novel model for anterior subcapsular cataract.. Molecular Vision. 13:457-469. 2007
- Attenuation of the Glucocorticoid Response during Ad5IL-12 Adenovirus Vector Treatment Enhances Natural Killer Cell–Mediated Killing of MHC Class I–Negative LNCaP Prostate Tumors. Cancer Research. 67:2290-2297. 2007
- IL-4 gene transfer to the small bowel serosa leads to intestinal inflammation and smooth muscle hyperresponsiveness. American Journal of Physiology - Gastrointestinal and Liver Physiology. 292:G385-G394. 2007
- Lung Development and Susceptibility to Chronic Obstructive Pulmonary Disease. Annals of the American Thoracic Society. 3:668-672. 2006
- Smad3 Signaling Involved in Pulmonary Fibrosis and Emphysema. Annals of the American Thoracic Society. 3:696-702. 2006
- Cell-specific Gene Expression in Patients with Usual Interstitial Pneumonia. American Journal of Respiratory and Critical Care Medicine. 174:557-565. 2006
- Gene Therapy for Pulmonary Diseases. Chest. 130:879-884. 2006
- Models of pulmonary fibrosis. Drug Discovery Today: Disease Models. 3:243-249. 2006
- Montelukast Treatment Attenuates the Increase in Myofibroblasts Following Low-Dose Allergen Challenge. Chest. 130:741-753. 2006
- Strategies targeting fibrosis in pulmonary disease. Drug Discovery Today: Therapeutic Strategies. 3:389-394. 2006
- Lens-Specific Expression of TGF-β Induces Anterior Subcapsular Cataract Formation in the Absence of Smad3. Investigative Ophthalmology and Visual Science. 47:3450-3450. 2006
- Severe Sepsis Exacerbates Cell-Mediated Immunity in the Lung Due to an Altered Dendritic Cell Cytokine Profile. American Journal of Pathology. 168:1940-1950. 2006
- Targeting Genes for Treatment in Idiopathic Pulmonary Fibrosis: Challenges and Opportunities, Promises and Pitfalls. Annals of the American Thoracic Society. 3:389-393. 2006
- Induction of a fibrogenic response in mouse colon by overexpression of monocyte chemoattractant protein 1. Gut. 55:662-670. 2006
- Comparative evaluation of two severe acute respiratory syndrome (SARS) vaccine candidates in mice challenged with SARS coronavirus. Journal of General Virology. 87:641-650. 2006
- Comparative evaluation of two severe acute respiratory syndrome (SARS) vaccine candidates in mice challenged with SARS coronavirus. Journal of General Virology. 87:641-650. 2006
- The transforming growth factor-beta (TGF-β) family and pulmonary fibrosis. Drug Discovery Today: Disease Mechanisms. 3:99-103. 2006
- Generation ofin vitroB-CLL specific HLA class I restricted CTL responses using autologous dendritic cells pulsed with necrotictumor lysate. Leukemia and Lymphoma. 47:297-306. 2006
- TGF-β and Smad3 Signaling Link Inflammation to Chronic Fibrogenesis. Journal of Immunology. 175:5390-5395. 2005
- Pulmonary Fibrosis. American Journal of Respiratory Cell and Molecular Biology. 33:9-13. 2005
- TGF-β1 gene transfer to the mouse colon leads to intestinal fibrosis. American Journal of Physiology - Gastrointestinal and Liver Physiology. 289:G116-G128. 2005
- Recent advances in immunotherapy of B-CLL using ex vivo modified dendritic cells. Hematology. 10:189-203. 2005
- Progressive Transforming Growth Factor β1–induced Lung Fibrosis Is Blocked by an Orally Active ALK5 Kinase Inhibitor. American Journal of Respiratory and Critical Care Medicine. 171:889-898. 2005
- Epithelial Expression of Profibrotic Mediators in a Model of Allergen-Induced Airway Remodeling. American Journal of Respiratory Cell and Molecular Biology. 32:99-107. 2005
- Bone Marrow‐Derived Dendritic Cell Vaccination of Dogs with Naturally Occurring Melanoma by Using Human gp100 Antigen. Journal of Veterinary Internal Medicine (JVIM). 19:56-63. 2005
- Bone Marrow–Derived Dendritic Cell Vaccination of Dogs with Naturally Occurring Melanoma by Using Human gp100 Antigen. Journal of Veterinary Internal Medicine (JVIM). 19:56-56. 2005
- Disruption of CD40-CD40 ligand pathway inhibits the development of intestinal muscle hypercontractility and protective immunity in nematode infection. American Journal of Physiology - Gastrointestinal and Liver Physiology. 288:G15-G22. 2005
- Proinflammatory properties of IL-4 in the intestinal microenvironment. American Journal of Physiology - Gastrointestinal and Liver Physiology. 288:G111-G117. 2005
- Severe acute respiratory syndrome coronavirus nucleocapsid protein expressed by an adenovirus vector is phosphorylated and immunogenic in mice. Journal of General Virology. 86:211-215. 2005
- The gene transfer of soluble VEGF type I receptor (Flt-1) attenuates peritoneal fibrosis formation in mice but not soluble TGF-β type II receptor gene transfer. American Journal of Physiology - Gastrointestinal and Liver Physiology. 288:G143-G150. 2005
- Cell-based cancer gene therapy: breaking tolerance or inducing autoimmunity?. Animal Health Research Reviews. 5:227-234. 2004
- Life-long systemic protection in mice vaccinated with and adenovirus IL-12 vector requires active infection, macrophages and intact lymph nodes. Vaccine. 23:247-257. 2004
- Connective Tissue Growth Factor Is Crucial to Inducing a Profibrotic Environment in “Fibrosis-Resistant” Balb/c Mouse Lungs. American Journal of Respiratory Cell and Molecular Biology. 31:510-516. 2004
- The human SCGB2A2 (Mammaglobin-1) promoter/enhancer in a helper-dependent adenovirus vector directs high levels of transgene expression in mammary carcinoma cells but not in normal nonmammary cells. Molecular Therapy. 10:758-767. 2004
- Lung fibroblast clones from normal and fibrotic subjects differ in hyaluronan and decorin production and rate of proliferation. International Journal of Biochemistry and Cell Biology. 36:1573-1584. 2004
- Smad3 Null Mice Develop Airspace Enlargement and Are Resistant to TGF-β-Mediated Pulmonary Fibrosis. Journal of Immunology. 173:2099-2108. 2004
- Study of cytokine induced neuropathology by high resolution proton NMR spectroscopy of rat urine. FEBS Letters. 568:49-54. 2004
- Costimulatory ligand 4-1BBL (CD137L) as an efficient adjuvant for human antiviral cytotoxic T cell responses. Proceedings of the National Academy of Sciences of the United States of America. 101:1291-1296. 2004
- Effects of adenoviral-mediated gene transfer of interleukin-10, interleukin-4, and transforming growth factor-β on the survival of axotomized retinal ganglion cells. Neuroscience. 125:903-920. 2004
- Overexpression of Tumor Necrosis Factor-α Diminishes Pulmonary Fibrosis Induced by Bleomycin or Transforming Growth Factor-β. American Journal of Respiratory Cell and Molecular Biology. 29:669-676. 2003
- Transfer of the Active Form of Transforming Growth Factor-β1 Gene to Newborn Rat Lung Induces Changes Consistent with Bronchopulmonary Dysplasia. American Journal of Pathology. 163:2575-2584. 2003
- Estradiol increases extracellular levels of vascular endothelial growth factor in vivo in murine mammary cancer. International Journal of Cancer. 107:535-540. 2003
- Coordinate expression of group II phospholipase A2 and the acute-phase proteins haptoglobin (HP) and α1-anti-chymotrypsin (ACH) by HepG2 cells. Clinical and Experimental Immunology. 108:175-180. 2003
- A phase I trial of adenovector-mediated delivery of interleukin-2 (AdIL-2) in high-risk localized prostate cancer. Cancer Gene Therapy. 10:755-763. 2003
- Adenoviral Gene Transfer of Connective Tissue Growth Factor in the Lung Induces Transient Fibrosis. American Journal of Respiratory and Critical Care Medicine. 168:770-778. 2003
- Transforming Growth Factor-β1-Mediated Neuroprotection against Excitotoxic Injuryin Vivo. Cerebrovascular and Brain Metabolism Reviews. 23:1174-1182. 2003
- Oestradiol enhances tumour regression induced by B7-1/IL-2 adenoviral gene transfer in a murine model of breast cancer. British Journal of Cancer. 89:385-390. 2003
- Inflammation in idiopathic pulmonary fibrosis. American Journal of Respiratory and Critical Care Medicine. 167:1037-1037. 2003
- Inflammation in idiopathic pulmonary fibrosis. American Journal of Respiratory and Critical Care Medicine. 167:1037-1037. 2003
- Estradiol Promotes Growth and Angiogenesis in Polyoma Middle T Transgenic Mouse Mammary Tumor Explants. Breast Cancer Research and Treatment. 78:1-6. 2003
- Protection Against Experimental Autoimmune Encephalomyelitis Generated by a Recombinant Adenovirus Vector Expressing the Vβ8.2 TCR Is Disrupted by Coadministration with Vectors Expressing Either IL-4 or -10. Journal of Immunology. 170:765-774. 2003
- Re-evaluation of Fibrogenic Cytokines in Lung Fibrosis. Current Pharmaceutical Design. 9:39-49. 2003
- TGF-β effects on epithelial ion transport and barrier: reduced Cl⁻ secretion blocked by a p38 MAPK inhibitor. American Journal of Physiology - Cell Physiology. 283:C1667-C1674. 2002
- Dysfunction and Remodeling of the Mouse Airway Persist after Resolution of Acute Allergen-Induced Airway Inflammation. American Journal of Respiratory Cell and Molecular Biology. 27:526-535. 2002
- TNF-alpha reduces cerebral blood volume and disrupts tissue homeostasis via an endothelin- and TNFR2-dependent pathway. Brain. 125:2446-2459. 2002
- Therapeutic Effect of Angiostatin Gene Transfer in a Murine Model of Endometriosis. American Journal of Pathology. 161:909-918. 2002
- Differences in the Fibrogenic Response after Transfer of Active Transforming Growth Factor-β1 Gene to Lungs of “Fibrosis-prone” and “Fibrosis-resistant” Mouse Strains. American Journal of Respiratory Cell and Molecular Biology. 27:141-150. 2002
- Intratumoral administration of an adenovirus expressing a kinase dead form of ErbB-2 inhibits tumor growth. Gene Therapy. 9:898-905. 2002
- Inflammatory Cytokines, Angiogenesis, and Fibrosis in the Rat Peritoneum. American Journal of Pathology. 160:2285-2294. 2002
- Suppression of tumorigenicity by adenovirus-mediated gene transfer of decorin. Oncogene. 21:3688-3695. 2002
- Suppression of tumorigenicity by adenovirus-mediated gene transfer of decorin. Oncogene. 21:3688-3695. 2002
- Adenoviral-Mediated Gene Transfer of Lymphotactin to the Lungs of Mice and Rats Results in Infiltration and Direct Accumulation of CD4⁺, CD8⁺, and NK Cells. Journal of Interferon and Cytokine Research. 22:573-582. 2002
- Inflammatory Mechanisms Are a Minor Component of the Pathogenesis of Idiopathic Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine. 165:1205-1206. 2002
- Antiangiogenic and Antifibrotic Gene Therapy in a Chronic Infusion Model of Peritoneal Dialysis in Rats. Journal of the American Society of Nephrology. 13:721-728. 2002
- A new direction in the pathogenesis of idiopathic pulmonary fibrosis?. Respiratory Research. 3:1. 2002
- Errors and incorrect procedures when utilizing χ² fitting criteria. Measurement Techniques. 45:572-581. 2002
- Miakron-2000 cetane-number-increasing additive for diesel fuels. Chemistry and Technology of Fuels and Oils (English translation of Khimiya i Tekhnologiya Topliv i Masel). 38:303-308. 2002
- Compartmentalized transgene expression of granulocyte-macrophage colony-stimulating factor (GM-CSF) in mouse lung enhances allergic airways inflammation. Clinical and Experimental Immunology. 113:157-165. 2001
- A Chronic Inflammatory Infusion Model of Peritoneal Dialysis in Rats. Advances in peritoneal dialysis. Conference on Peritoneal Dialysis. 21:368-372. 2001
- Gene Transfer of Transforming Growth Factor-β1 to the Rat Peritoneum. Journal of the American Society of Nephrology. 12:2029-2039. 2001
- Adenoviral Vector Expressing Murine Angiostatin Inhibits a Model of Breast Cancer Metastatic Growth in the Lungs of Mice. American Journal of Pathology. 159:1137-1147. 2001
- Budesonide Enhances Repeated Gene Transfer and Expression in the Lung with Adenoviral Vectors. American Journal of Respiratory and Critical Care Medicine. 164:866-872. 2001
- IL-12 gene transfer alters gut physiology and host immunity in nematode-infected mice. American Journal of Physiology - Gastrointestinal and Liver Physiology. 281:G102-G110. 2001
- Transient expression of IL-1β induces acute lung injury and chronic repair leading to pulmonary fibrosis. Journal of Clinical Investigation. 107:1529-1536. 2001
- Proteoglycans decorin and biglycan differentially modulate TGF-β-mediated fibrotic responses in the lung. American Journal of Physiology - Lung Cellular and Molecular Physiology. 280:L1327-L1334. 2001
- Combined Treatment of a Murine Breast Cancer Model with Type 5 Adenovirus Vectors Expressing Murine Angiostatin and IL-12: A Role for Combined Anti-Angiogenesis and Immunotherapy. Journal of Immunology. 166:6212-6217. 2001
- Adenovector engineered interleukin-2 expressing autologous plasma cell vaccination after high-dose chemotherapy for multiple myeloma - a phase 1 study. Leukemia. 15:846-854. 2001
- Behavioral Effects of Infection with IL-6 Adenovector. Brain, Behavior, and Immunity. 15:25-42. 2001
- Transient Transgene Expression of Decorin in the Lung Reduces the Fibrotic Response to Bleomycin. American Journal of Respiratory and Critical Care Medicine. 163:770-777. 2001
- Transient transgene expression of decorin in the lung reduces the fibrotic response to bleomycin. American Journal of Respiratory and Critical Care Medicine. 163:770-777. 2001
- Combined CXC chemokine and interleukin-12 gene transfer enhances antitumor immunity. Gene Therapy. 8:282-290. 2001
- Dendritic cells expressing TGFβ/IL-10, and CHO cells with OX-2, increase graft survival. Transplantation Proceedings. 33:1565-1566. 2001
- Induction of ErbB-2/neu-specific protective and therapeutic antitumor immunity using genetically modified dendritic cells: enhanced efficacy by cotransduction of gene encoding IL-12. Gene Therapy. 8:316-323. 2001
- Immunotherapy of spontaneous type 1 diabetes in nonobese diabetic mice by systemic interleukin-4 treatment employing adenovirus vector-mediated gene transfer. Gene Therapy. 7:1840-1846. 2000
- Recombinant adenovirus vectors expressing interleukin‐5 and ‐6 specifically enhance mucosal immunoglobulin A responses in the lung. Immunology. 101:388-396. 2000
- Contrasting effects of myeloid dendritic cells transduced with an adenoviral vector encoding interleukin‐10 on organ allograft and tumour rejection. Immunology. 101:233-241. 2000
- Mannose 6-Phosphate/Insulin-like Growth Factor II Receptor Is a Death Receptor for Granzyme B during Cytotoxic T Cell–Induced Apoptosis. Cell. 103:491-500. 2000
- Interleukin (IL)-5 but Not Immunoglobulin E Reconstitutes Airway Inflammation and Airway Hyperresponsiveness in IL-4–Deficient Mice. American Journal of Respiratory Cell and Molecular Biology. 23:327-334. 2000
- Genetically modified dendritic cells prime autoreactive T cells through a pathway independent of CD40L and interleukin 12: implications for cancer vaccines.. Cancer Research. 60:3247-3253. 2000
- Reciprocal actions of interleukin‐6 and brain‐derived neurotrophic factor on rat and mouse primary sensory neurons. European Journal of Neuroscience. 12:1891-1899. 2000
- Synergy in Induction of Increased Renal Allograft Survival after Portal Vein Infusion of Dendritic Cells Transduced to Express TGFβ and IL-10, along with Administration of CHO Cells Expressing the Regulatory Molecule OX-2. Clinical Immunology. 95:182-189. 2000
- Gene Vectors for Cytokine Expression In Vivo. Current Pharmaceutical Design. 6:613-632. 2000
- Transgenic expression of granulocyte-macrophage colony-stimulating factor induces the differentiation and activation of a novel dendritic cell population in the lung. Blood. 95:2337-2345. 2000
- Interleukin 10 gene transfer prevents experimental colitis in rats. Gut. 46:344-349. 2000
- Adenoviral-mediated Gene Transfer to Mouse Salivary Glands. Journal of Dental Research. 79:701-708. 2000
- Transient Transgenic Approaches for Investigating the Role of Granulocyte- Macrophage Colony-Stimulating Factor in Pulmonary Inflammatory and Immune Diseases. Methods in Molecular Medicine. 44:161-178. 2000
- Enhanced Immune Response to the Melanoma Antigen gp100 Using Recombinant Adenovirus-Transduced Dendritic Cells. Cellular Immunology. 198:131-138. 1999
- Transient Gene Transfer of Non-ELR Chemokines to Rodent Lung Induces Mononuclear Cell Accumulation and Activation. Journal of Interferon and Cytokine Research. 19:1381-1390. 1999
- Adenovirus Vector Expressing Mouse Oncostatin M Induces Acute-Phase Proteins and TIMP-1 ExpressionIn Vivoin Mice. Journal of Interferon and Cytokine Research. 19:1195-1205. 1999
- Spatial-specific TGF-β1 adenoviral expression determines morphogenetic phenotypes in embryonic mouse lung. European Journal of Cell Biology. 78:715-725. 1999
- A p75 tumor necrosis factor receptor-specific mutant of murine tumor necrosis factor α expressed from an adenovirus vector induces an antitumor response with reduced toxicity. Cancer Gene Therapy. 6:465-474. 1999
- Adenovirus-mediated decorin gene transfer prevents TGF-beta-induced inhibition of lung morphogenesis. American Journal of Physiology - Lung Cellular and Molecular Physiology. 277:L412-L422. 1999
- Adenovirus-mediated decorin gene transfer prevents TGF-β-induced inhibition of lung morphogenesis. American Journal of Physiology. 277:L412-L422. 1999
- Endogenous interleukin‐6 contributes to hypersensitivity to cutaneous stimuli and changes in neuropeptides associated with chronic nerve constriction in mice. European Journal of Neuroscience. 11:2243-2253. 1999
- A Randomized Controlled Trial on the Effect of Inhaled Corticosteroids on Airways Inflammation in Adult Cigarette Smokers. Chest. 115:1271-1277. 1999
- Adenoviral-Mediated Gene Transfer of Interleukin-6 in Rat Lung Enhances Antiviral Immunoglobulin A and G Responses in Distinct Tissue Compartments. Biochemical and Biophysical Research Communications. 258:332-335. 1999
- Secretory leukocyte proteinase inhibitor is preferentially increased in patients with acute respiratory distress syndrome. European Respiratory Journal. 13:1029-1029. 1999
- Secretory leukocyte proteinase inhibitor is preferentially increased in patients with acute respiratory distress syndrome. European Respiratory Journal. 13:1029-1036. 1999
- Macrophage inflammatory protein-2 gene therapy attenuates adenovirus- and acetaminophen-mediated hepatic injury. Gene Therapy. 6:573-584. 1999
- Murine dendritic cells transduced with an adenoviral vector expressing a defined tumor antigen can overcome anti-adenovirus neutralizing immunity and induce effective tumor regression.. International Journal of Oncology. 14:771-776. 1999
- Adenoviral Vectors Expressing Lymphotactin and Interleukin 2 or Lymphotactin and Interleukin 12 Synergize to Facilitate Tumor Regression in Murine Breast Cancer Models. Human Gene Therapy. 10:697-709. 1999
- Adenovector-mediated gene delivery of interleukin-2 in metastatic breast cancer and melanoma: results of a phase 1 clinical trial. Gene Therapy. 6:350-363. 1999
- Enhancement of dendritic cell tolerogenicity by genetic modification using adenoviral vectors encoding cDNA for TGFβ1. Transplantation Proceedings. 31:1195-1195. 1999
- Neurotransmitters modulate cytokine-stimulated interleukin 6 secretion in rat intestinal smooth muscle cells. Gastroenterology. 116:346-353. 1999
- A Single Intramuscular Injection with an Adenovirus- Expressing IL-12 Protects BALB/c Mice AgainstLeishmania majorInfection, While Treatment with an IL-4-Expressing Vector Increases Disease Susceptibility in B10.D2 Mice. Journal of Immunology. 162:753-760. 1999
- Cytokines and pulmonary inflammatory and immune diseases.. Histology and Histopathology. 14:185-201. 1999
- PHENOTYPE, FUNCTION, AND IN VIVO MIGRATION AND SURVIVAL OF ALLOGENEIC DENDRITIC CELL PROGENITORS GENETICALLY ENGINEERED TO EXPRESS TGF-??1,2. Transplantation. 66:1810-1817. 1998
- Enhanced Interleukin-2 Gene Transfer Immunotherapy of Breast Cancer by Coexpression of B7-1 and B7-2. Journal of Interferon and Cytokine Research. 18:927-937. 1998
- Intratumoral coinjection of adenoviral vectors expressing IL-2 and IL-12 results in enhanced frequency of regression of injected and untreated distal tumors. Gene Therapy. 5:1400-1409. 1998
- Circulating, but not local lung, IL-5 is required for the development of antigen-induced airways eosinophilia.. Journal of Clinical Investigation. 102:1132-1141. 1998
- Transfer of Tumor Necrosis Factor-α to Rat Lung Induces Severe Pulmonary Inflammation and Patchy Interstitial Fibrogenesis with Induction of Transforming Growth Factor-β1 and Myofibroblasts. American Journal of Pathology. 153:825-832. 1998
- Transient Gene Transfer of IL-12 Regulates Chemokine Expression and Disease Severity in Experimental Arthritis. Journal of Immunology. 160:4615-4619. 1998
- Monitoring soluble interleukin-2 receptor levels in related and unrelated donor allogeneic bone marrow transplantation. Bone Marrow Transplantation. 21:769-773. 1998
- A Double Recombinant Adenovirus Expressing the Costimulatory Molecule B7-1 (Murine) and Human IL-2 Induces Complete Tumor Regression in a Murine Breast Adenocarcinoma Model. Journal of Immunology. 160:2531-2538. 1998
- Adenovirus-Mediated Interleukin-10 Gene Transfer Inhibits Post-Transplant Fibrous Airway Obliteration in an Animal Model of Bronchiolitis Obliterans. Human Gene Therapy. 9:541-551. 1998
- Adenovirus-mediated expression of an elastase-specific inhibitor (elafin): a comparison of different promoters. Gene Therapy. 5:352-360. 1998
- Epithelium-specific adenoviral transfer of a dominant-negative mutant TGF-β type II receptor stimulates embryonic lung branching morphogenesis in culture and potentiates EGF and PDGF-AA. Cells and Development. 72:89-100. 1998
- Tumour therapy in mice using adenovirus vectors expressing human TNFa.. International Journal of Oncology. 12:509-515. 1998
- In Vivo Adenoviral-Mediated Gene Transfer of Interleukin-2 in Cutaneous Plasmacytoma. Blood. 91:1095-1097. 1998
- IL-6 is an antiinflammatory cytokine required for controlling local or systemic acute inflammatory responses.. Journal of Clinical Investigation. 101:311-320. 1998
- Bronchial myofibroblasts and tissue remodelling in asthma.. Canadian Respiratory Journal. 5:59-61. 1998
- Effects on brain tumor cell proliferation by an adenovirus vector that bears the Interleukin-4 gene. Journal of NeuroVirology. 4:237-241. 1998
- Intradermal transgenic expression of granulocyte-macrophage colony-stimulating factor induces neutrophilia, epidermal hyperplasia, Langerhans' cell/macrophage accumulation, and dermal fibrosis.. Laboratory Investigation. 77:615-622. 1997
- Therapeutic effects of interleukin-4 gene transfer in experimental inflammatory bowel disease.. Journal of Clinical Investigation. 100:2766-2776. 1997
- Transfer of granulocyte-macrophage colony-stimulating factor gene to rat lung induces eosinophilia, monocytosis, and fibrotic reactions. Pneumologie. 51:396. 1997
- ANTI-INTERLEUKIN-12 THERAPY PROTECTS MICE IN LETHAL ENDOTOXEMIA BUT IMPAIRS BACTERIAL CLEARANCE IN MURINE ESCHERICHIA COLI PERITONEAL SEPSIS. Shock. 8:349-356. 1997
- Tumour immunotherapy using an adenoviral vector expressing a membrane-bound mutant of murine TNFα. Gene Therapy. 4:1181-1188. 1997
- Pre-existing immunity to adenovirus does not prevent tumor regression following intratumoral administration of a vector expressing IL-12 but inhibits virus dissemination. Gene Therapy. 4:1069-1076. 1997
- Interleukin 12 and B7-1 costimulatory molecule expressed by an adenovirus vector act synergistically to facilitate tumor regression. Proceedings of the National Academy of Sciences of the United States of America. 94:10889-10894. 1997
- Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung.. Journal of Clinical Investigation. 100:768-776. 1997
- Construction and Characterization of a Replication-Deficient Adenovirus Expressing Rat-Soluble Interleukin-6 Receptor. Molecular Medicine. 3:519-529. 1997
- A Phase I Study of Adenovirus Mediated Gene Transfer of Interleukin 2 cDNA into Metastatic Breast Cancer or Melanoma. The Toronto Hospital, Toronto, Ontario, Canada. Human Gene Therapy. 8:1403-1414. 1997
- Dendritic Cells Transduced with an Adenoviral Vector Encoding a Model Tumor-Associated Antigen for Tumor Vaccination. Human Gene Therapy. 8:1355-1363. 1997
- Adenovirus-mediated gene transfer of the proteoglycan biglycan induces fibroblastic responses in the lung.. Chest. 111:137S. 1997
- In vivo adenovirus-mediated expression of human pre-elafin, a potent neutrophil elastase inhibitor.. Chest. 111:128S-129S. 1997
- Oncostatin M, but Not Interleukin-6 or Leukemia Inhibitory Factor, Stimulates Expression of Alpha1-Proteinase Inhibitor in A549 Human Alveolar Epithelial Cells. Journal of Interferon and Cytokine Research. 17:337-346. 1997
- Secretory leukocyte proteinase inhibitor is a major leukocyte elastase inhibitor in human neutrophils. Journal of Leukocyte Biology. 61:695-702. 1997
- Transient Gene Transfer and Expression in the Lung. Chest. 111:89S-94S. 1997
- Antibodies to rat soluble IL‐6 receptor stimulate B9 hybridoma cell proliferation. FEBS Letters. 408:182-186. 1997
- Transgene-induced production of IL-4 alters the development and collagen expression of T helper cell 1-type pulmonary granulomas.. Journal of Immunology. 158:4478-4484. 1997
- Intramarrow Cytokine Gene Transfer by Adenoviral Vectors in Dogs. Human Gene Therapy. 8:545-553. 1997
- Adenoviral vector-mediated interleukin-10 expression in vivo: intramuscular gene transfer inhibits cytokine responses in endotoxemia. Gene Therapy. 4:140-149. 1997
- Overexpression of granulocyte-macrophage colony-stimulating factor induces pulmonary granulation tissue formation and fibrosis by induction of transforming growth factor-beta 1 and myofibroblast accumulation.. American Journal of Pathology. 150:59-66. 1997
- Reduced Preference for Sucrose in Autoimmune Mice. Brain Research Bulletin. 44:155-165. 1997
- Overexpression of RANTES using a recombinant adenovirus vector induces the tissue-directed recruitment of monocytes to the lung.. Journal of Immunology. 157:5076-5084. 1996
- Characterization and Biologic Activities of Recombinant Rat Soluble Interleukin-6 Receptor. Journal of Interferon and Cytokine Research. 16:973-981. 1996
- Direct Intratumoral Injection of an Adenovirus Expressing Interleukin-12 Induces Regression and Long-Lasting Immunity That Is Associated with Highly Localized Expression of Interleukin-12. Human Gene Therapy. 7:1995-2002. 1996
- Adenoviral gene transfer of macrophage inflammatory protein-2 in rat lung.. American Journal of Pathology. 149:1395-1403. 1996
- Elafin/elastase-specific inhibitor in bronchoalveolar lavage of normal subjects and Farmer's lung. American Journal of Respiratory and Critical Care Medicine. 154:1092-1098. 1996
- Elafin/elastase-specific inhibitor in bronchoalveolar lavage of normal subjects and farmer's lung.. American Journal of Respiratory and Critical Care Medicine. 154:1092-1098. 1996
- IL-12 gene therapy protects mice in lethal Klebsiella pneumonia.. Journal of Immunology. 157:3006-3012. 1996
- Recombinant Human Adenovirus with Rat MIP‐2 Gene Insertion Causes Prolonged PMN Recruitment to the Murine Brain. European Journal of Neuroscience. 8:1803-1811. 1996
- Vector-Derived Expression of Recombinant Rat Interleukin-6. Protein Expression and Purification. 7:269-274. 1996
- Gene transfer for cytokine functional studies in the lung: the multifunctional role of GM-CSF in pulmonary inflammation. Journal of Leukocyte Biology. 59:481-488. 1996
- Regulation of signal transducer, gp130 and the lif receptor in acute inflammation in vivo. Cytokine. 8:283-287. 1996
- Measurement of Interleukin 6. Current Protocols in Immunology. 17:Unit-6.6. 1996
- Transfer of granulocyte-macrophage colony-stimulating factor gene to rat lung induces eosinophilia, monocytosis, and fibrotic reactions.. Journal of Clinical Investigation. 97:1102-1110. 1996
- Construction of a Double Recombinant Adenovirus Vector Expressing a Heterodimeric Cytokine:In VitroandIn VivoProduction of Biologically Active Interleukin-12. Human Gene Therapy. 7:333-342. 1996
- Metabolic changes in rats during a continuous infusion of recombinant interleukin-1. American Journal of Physiology - Endocrinology and Metabolism. 270:E305-E312. 1996
- Metabolic changes in rats during a continuous infusion of recombinant interleukin-1. American Journal of Physiology. 270:E305-E312. 1996
- Modulation of the Anchorage-Independent Phenotype of Human Lung Fibroblasts Obtained from Fibrotic Tissue Following Culture with Retinoid and Corticosteroid. Experimental Lung Research. 22:231-244. 1996
- Murine Cardiotrophin-1 Stimulates the Acute-Phase Response in Rat Hepatocytes and H35 Hepatoma Cells. Journal of Interferon and Cytokine Research. 16:69-75. 1996
- AN ADENOVIRAL VECTOR EXPRESSING INTERLEUKIN-4 MODULATES TUMORIGENICITY AND INDUCES REGRESSION IN A MURINE BREAST-CANCER MODEL. International Journal of Oncology. 7:1253-1260. 1995
- STEROID INHIBITION OF CYTOKINE-MEDIATED VASODILATION AFTER WARM HEART-SURGERY. Circulation. 92:347-353. 1995
- Steroid Inhibition of Cytokine-Mediated Vasodilation After Warm Heart Surgery. Circulation. 92:347-353. 1995
- IL-6 stimulates vitronectin gene expression in vivo.. Journal of Immunology. 155:3180-3185. 1995
- Intratumoral injection of an adenovirus expressing interleukin 2 induces regression and immunity in a murine breast cancer model.. Proceedings of the National Academy of Sciences of the United States of America. 92:8522-8526. 1995
- Cytokines oncostatin M and interleukin 1 regulate the expression of the IL-6 receptor (gp80, gp130). Cytokine. 7:503-509. 1995
- The use of adenoviral vectors for gene therapy and gene transfer in vivo. Current Opinion in Biotechnology. 6:590-595. 1995
- Regulation of secretory leukocyte proteinase inhibitor (SLPI) and elastase-specific inhibitor (ESI/elafin) in human airway epithelial cells by cytokines and neutrophilic enzymes.. American Journal of Respiratory Cell and Molecular Biology. 11:733-741. 1994
- Adenovirus-mediated cytokine gene transfer at tissue sites. Overexpression of IL-6 induces lymphocytic hyperplasia in the lung.. Journal of Immunology. 153:4059-4069. 1994
- TNF-alpha production by eosinophils in upper airways inflammation (nasal polyposis).. Journal of Immunology. 153:2278-2289. 1994
- Growth and Colony‐Stimulating Factors Mediate Eosinophil Fibroblast Interactions in Chronic Airway Inflammationa. Annals of the New York Academy of Sciences. 725:83-90. 1994
- A role for CD4⁺ T cells in the pathogenesis of skin fibrosis in tight skin mice. European Journal of Immunology. 24:1463-1466. 1994
- Systemic administration of ciliary neurotrophic factor induces cachexia in rodents.. Journal of Clinical Investigation. 93:2632-2638. 1994
- Anchorage-independent colony growth of pulmonary fibroblasts derived from fibrotic human lung tissue.. Journal of Clinical Investigation. 93:1525-1532. 1994
- Cytokine expression by neutrophils and macrophages in vivo: endotoxin induces tumor necrosis factor-alpha, macrophage inflammatory protein-2, interleukin-1 beta, and interleukin-6 but not RANTES or transforming growth factor-beta 1 mRNA expression in acute lung inflammation.. American Journal of Respiratory Cell and Molecular Biology. 10:148-153. 1994
- The acute phase response. Trends in Immunology. 15:74-80. 1994
- Construction of recombinant human type 5 adenoviruses expressing rodent IL-6 genes. An approach to investigate in vivo cytokine function.. Journal of Immunology. 151:5145-5153. 1993
- Polymorphonuclear leukocytes as a significant source of tumor necrosis factor-alpha in endotoxin-challenged lung tissue.. American Journal of Pathology. 143:1009-1015. 1993
- CYTOKINES .4. CYTOKINES AND PULMONARY FIBROSIS. Thorax. 48:931-935. 1993
- Cytokines and pulmonary fibrosis.. Thorax. 48:931-935. 1993
- Leukemia inhibitory factor production by rat mast cells. European Journal of Immunology. 23:2116-2120. 1993
- Lipopolysaccharide Induces Expression of Granulocyte/Macrophage Colony-stimulating Factor, Interleukin-8, and Interleukin-6 in Human Nasal, but Not Lung, Fibroblasts: Evidence for Heterogeneity within the Respiratory Tract. American Journal of Respiratory Cell and Molecular Biology. 9:255-263. 1993
- Selective regulation of metalloproteinase inhibitor (TIMP-1) by oncostatin M in fibroblasts in culture.. Journal of Immunology. 150:5596-5603. 1993
- Cytokines in lung and airways fibrosis.. Regional immunology. 5:201-206. 1993
- Regulation of IL-6 and the hepatic IL-6 receptor in acute inflammation in vivo. Cytokine. 5:1-7. 1993
- Type 1 plasminogen activator inhibitor is not an acute phase reactant in rats. Lack of IL-6- and hepatocyte-dependent synthesis.. Journal of Immunology. 150:225-235. 1993
- Accumulation of Type 1 Plasminogen Activator Inhibitor and Vitronectin at Sites of Cellular Necrosis and Inflammation. Annals of the New York Academy of Sciences. 667:173-177. 1992
- Bronchial Epithelial Cell-derived Cytokines (G-CSF and GM-CSF Promote the Survical of Peripheral Blood Neutrophils In Vitro. American Journal of Respiratory Cell and Molecular Biology. 7:507-514. 1992
- Serum T‐Kininogen Levels Increase Shortly before Death. Annals of the New York Academy of Sciences. 663:479-480. 1992
- 46TH FORUM IN IMMUNOLOGY - DISCUSSION. Research in Immunology. 143:779-783. 1992
- Alpha 2-macroglobulin expression in the mesometrial decidua and its regulation by decidual luteotropin and prolactin.. Endocrinology. 131:1321-1328. 1992
- Evidence that interleukin-6 does not play a role in the stimulation of platelet production after induction of acute thrombocytopenia. Blood. 80:346-351. 1992
- Eosinophils in chronically inflamed human upper airway tissues express transforming growth factor beta 1 gene (TGF beta 1).. Journal of Clinical Investigation. 89:1662-1668. 1992
- IL-1 beta and IL-6 gene expression in alveolar macrophages: modulation by extracellular matrices. American Journal of Physiology. 262:L600-L605. 1992
- IL-1-BETA AND IL-6 GENE-EXPRESSION IN ALVEOLAR MACROPHAGES - MODULATION BY EXTRACELLULAR MATRICES. American Journal of Physiology. 262:L600-L605. 1992
- Serum T-kininogen levels increase two to four months before death.. Journal of Biological Chemistry. 267:10665-10669. 1992
- Recombinant oncostatin M stimulates the production of acute phase proteins in HepG2 cells and rat primary hepatocytes in vitro.. Journal of Immunology. 148:1731-1736. 1992
- AIRWAY INFLAMMATION ROUND-TABLE - GENERAL DISCUSSION. American Review of Respiratory Disease. 145:S53-S57. 1992
- FIBROBLASTS AND OTHER STRUCTURAL CELLS IN AIRWAY INFLAMMATION. American Review of Respiratory Disease. 145:S14-S17. 1992
- Fibroblasts and Other Structural Cells in Airway Inflammation. American Journal of Respiratory and Critical Care Medicine. 145:S14-S17. 1992
- Human Upper Airway Structural Cell-derived Cytokines Support Human Peripheral Blood Monocyte Survival: A Potential Mechanism for Monocyte/Macrophage Accumulation in the Tissue. American Journal of Respiratory Cell and Molecular Biology. 6:212-218. 1992
- ACUTE-PHASE RESPONSES - GENERAL DISCUSSION. Ciba Foundation symposium. 167:156-159. 1992
- CYTOKINES AND BINDING-PROTEINS IN THE CIRCULATION - GENERAL DISCUSSION. Ciba Foundation symposium. 167:260-264. 1992
- IL6 and the acute phase reaction. Research in Immunology. 143:755-759. 1992
- INTERLEUKIN-6, LEUKEMIA INHIBITORY FACTOR AND GRANULOCYTE COLONY-STIMULATING FACTOR - GENERAL DISCUSSION. Ciba Foundation symposium. 167:201-203. 1992
- THE EFFECTS OF LEUKEMIA INHIBITORY FACTOR AND INTERLEUKIN-6 ON VASCULAR FUNCTION. Ciba Foundation symposium. 167:203-204. 1992
- The relationship between cadaver donor interleukin 6 levels and delayed graft function in kidney transplantation.. Transplantation. 53:222-223. 1992
- Granulocyte/Macrophage Colony-stimulating Factor (GM-CSF) Gene Expression by Eosinophils in Nasal Polyposis. American Journal of Respiratory Cell and Molecular Biology. 5:505-510. 1991
- Interleukin-6 is a centrally acting endogenous pyrogen in the rat. Canadian Journal of Physiology and Pharmacology. 69:1465-1469. 1991
- Promotion of Eosinophil Survival by Human Bronchial Epithelial Cells and its Modulation by Steroids. American Journal of Respiratory Cell and Molecular Biology. 4:525-531. 1991
- Effects of interleukin-6 and leukemia inhibitory factor on the acute phase response and DNA synthesis in cultured rat hepatocytes.. Journal of Interferon and Cytokine Research. 10:23-26. 1991
- The expression of interleukin‐6 by a rat macrophage‐derived cell line. FEBS Letters. 280:277-280. 1991
- Monocyte-Macrophage Differentiation Induced by Human Upper Airway Epithelial Cells. American Journal of Respiratory Cell and Molecular Biology. 4:255-263. 1991
- The acute phase protein response during parasitic infection. Trends in Parasitology. 7:7-12. 1991
- Autocrine activity of interleukin 6 secreted by hepatocarcinoma cell lines.. Molecular biology & medicine. 8:141-156. 1991
- Counteracting effects of dexamethasone and α₂‐macroglobulin on inhibition of proliferation of normal and neoplastic rat hepatocytes by transforming growth factors‐β type 1 and type 2. International Journal of Cancer. 47:311-316. 1991
- Cytokine control of acute phase protein expression.. European Cytokine Network. 2:89-98. 1991
- Human Upper Airway Epithelial Cell-Derived Granulocyte-Macrophage Colony-Stimulating Factor Induces Histamine-Containing Cell Differentiation of Human Progenitor Cells. International Archives of Allergy and Applied Immunology. 95:376-384. 1991
- Neutrophilic Differentiation Induced by Human Upper Airway Fibroblast-derived Granulocyte/Macrophage Colony-stimulating Factor (GM-CSF). American Journal of Respiratory Cell and Molecular Biology. 4:11-17. 1991
- Structural Cell-Derived Cytokines in Allergic Inflammation. International Archives of Allergy and Applied Immunology. 94:127-132. 1991
- The acute phase protein response during parasitic infection. Trends in Immunology. 12:A7-A12. 1991
- Macrophages in rat gut: Reply. Journal of Histochemistry and Cytochemistry. 38:1391. 1990
- MACROPHAGES IN RAT GUT - RESPONSE. Journal of Histochemistry and Cytochemistry. 38:1391-1391. 1990
- Transforming growth factor‐β and epidermal growth factor modulate basal and interleukin‐6‐induced amino acid uptake and acute phase protein synthesis in cultured rat hepatocytes. FEBS Letters. 266:48-50. 1990
- Characterization of Nippostrongylus brasiliensis Infection in Different Strains of Mice. Journal of Parasitology. 76:377-377. 1990
- Production of interleukin 6 by hepatoma cells.. Molecular biology & medicine. 7:273-285. 1990
- IL-6 functions as an exocrine hormone in inflammation. Hepatocytes undergoing acute phase responses require exogenous IL-6.. Journal of Immunology. 144:3804-3808. 1990
- Alpha 2-macroglobulin and serum preferentially counteract the mitoinhibitory effect of transforming growth factor-beta 2 in rat hepatocytes.. Laboratory Investigation. 62:545-551. 1990
- Regulation of hepatic acute phase plasma protein genes by hepatocyte stimulating factors and other mediators of inflammation.. Molecular biology & medicine. 7:147-159. 1990
- The acute-phase protein response in parasite infection. Nippostrongylus brasiliensis and Trichinella spiralis in the rat.. Immunology. 69:588-595. 1990
- Characterization of nonspecific esterase activity in macrophages and intestinal epithelium of the rat.. Journal of Histochemistry and Cytochemistry. 38:1-6. 1990
- Epidermal growth factor and transforming growth factor-β differently modulate the acute phase response elicited by interleukin-6 in cultured liver cells from man, rat and mouse. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 95:41-45. 1990
- The acute phase response of the liver in inflammation.. Progress in Liver Diseases. 9:89-116. 1990
- Hormonal Regulation and Tissue-Specific Localization of α₂-Macroglobulin in Rat Ovarian Follicles and Corpora Lutea*. Endocrinology. 125:2985-2995. 1989
- Fibrosis pulmonar: perspectivas actuales. Archivos de Bronconeumologia. 25:336-344. 1989
- Human Lung Fibroblast-derived Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) Mediates Eosinophil Survival In Vitro. American Journal of Respiratory Cell and Molecular Biology. 1:289-295. 1989
- Polycarbonate membranes: a novel surface for solid-phase determinations with utility in field format serological assays. Journal of Immunological Methods. 123:185-192. 1989
- IFN-BETA-2 BSF2 IL-6 IS THE MONOCYTE-DERIVED HSF THAT REGULATES RECEPTOR-SPECIFIC ACUTE PHASE GENE-REGULATION IN HEPATOCYTES. Annals of the New York Academy of Sciences. 557:46-59. 1989
- IFNβ2/BSF2/IL‐6 Is the Monocyte‐derived HSF That Regulates Receptor‐specific Acute Phase Gene Regulation in Hepatocytes^a. Annals of the New York Academy of Sciences. 557:46-59. 1989
- Regulation of Rat Liver Acute Phase Genes by Interleukin‐6 and Production of Hepatocyte Stimulating Factors by Rat Hepatoma Cells^a. Annals of the New York Academy of Sciences. 557:317-331. 1989
- Antigen-induced Lung Solute Clearance in Rats Is Dependent on Capsaicin-sensitive Nerves. American Journal of Respiratory and Critical Care Medicine. 139:401-406. 1989
- Leukocyte endogenous mediator fails to alter protein dynamics in a model of liver dysfunction.. Translational Research. 113:211-220. 1989
- Different preparations of natural and recombinant human interleukin-6 (ifn-β2, bsf-2) similarly stimulate acute phase protein synthesis and uptake of α-aminoisobutyric acid by cultured rat hepatocytes. International Journal of Biochemistry and Cell Biology. 21:361-366. 1989
- Hemopoietic function of the microenvironment in chronic airway inflammation.. Agents and Actions Supplements. 28:85-95. 1989
- Regulation of rat liver acute phase genes by interleukin-6 and production of hepatocyte stimulating factors by rat hepatoma cells.. Annals of the New York Academy of Sciences. 557:317-329. 1989
- The cascade of inflammatory cytokines regulating synthesis of acute phase proteins.. Tokai Journal of Experimental and Clinical Medicine. 13:255-264. 1988
- A novel monoclonal antibody based diagnostic test for alpha-thalassemia- 1 carriers due to the (-SEA/) deletion. Blood. 72:1589-1594. 1988
- Effect of histamine on proliferation of normal human adult lung fibroblasts.. Thorax. 43:552-558. 1988
- Inhibitory effect of human recombinant interferon gamma on synthesis of acute phase proteins in human hepatoma Hep G2 cells stimulated by leukocyte cytokines, TNF alpha and IFN-beta 2/BSF-2/IL-6.. IUBMB Life. 17:17-23. 1988
- Solute Movement across the Alveolar-Capillary Membrane after Intratracheally Administered Bleomycin in Rats. American Journal of Respiratory and Critical Care Medicine. 138:96-100. 1988
- SpontaneousIn VitroRelease of Alveolar-Macrophage Cytokines after the Intratracheal Instillation of Bleomycin in Rats: Characterization and Kinetic Studies. American Journal of Respiratory and Critical Care Medicine. 137:1135-1140. 1988
- Heterogeneous Proliferative Characteristics of Human Adult Lung Fibroblast Lines and Clonally Derived Fibroblasts from Control and Fibrotic Tissue. American Journal of Respiratory and Critical Care Medicine. 137:579-584. 1988
- An association between schistosomes and contrapsin, a mouse serine protease inhibitor (serpin). Parasitology. 96:99-109. 1988
- An alternative regulatory pathway of the acute phase response: the role of fibroblast-derived interferon-β 2. Cellular and Molecular Life Sciences. 44:9-10. 1988
- Cellular interactions in lung inflammation and immunity.. Postgraduate Medical Journal. 64 Suppl 4:111-119. 1988
- Interaction among hepatocyte-stimulating factors, interleukin 1, and glucocorticoids for regulation of acute phase plasma proteins in human hepatoma (HepG2) cells.. Journal of Immunology. 139:4122-4128. 1987
- The Role of Rat C3 and C3 Receptor-Bearing Alveolar Macrophages in In vitro Attrition of Infective Larvae of Nippostrongylus brasiliensis. Journal of Parasitology. 73:1270-1270. 1987
- Interferon beta 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells.. Proceedings of the National Academy of Sciences of the United States of America. 84:7251-7255. 1987
- Role of Epidermal Cell Thymocyte-Activating Factor in the Proliferation and Differentiation of Murine B Cells. Journal of Leukocyte Biology. 42:222-229. 1987
- Comparison of the acute phase response of cultured Morris hepatoma 7777 cells and of rat hepatocytes.. International Journal of Experimental Pathology. 68:485-492. 1987
- Alveolar Macrophage/Peripheral Blood Monocyte-Derived Factors Modulate Proliferation of Primary Lines of Human Lung Fibroblasts. Journal of Leukocyte Biology. 42:51-60. 1987
- Distinct sets of acute phase plasma proteins are stimulated by separate human hepatocyte-stimulating factors and monokines in rat hepatoma cells.. Journal of Biological Chemistry. 262:9756-9768. 1987
- MAST-CELL INVOLVEMENT IN VARIOUS INFLAMMATORY PROCESSES. American Review of Respiratory Disease. 135:S5-S8. 1987
- Mast cell involvement in various inflammatory processes.. American Journal of Respiratory and Critical Care Medicine. 135:S5-S8. 1987
- Limited effects of recombinant human and murine interleukin 1 and tumour necrosis factor on production of acute phase proteins by cultured rat hepatocytes.. IUBMB Life. 14:553-560. 1987
- Purified interleukin-1 (IL-1) from human monocytes stimulates acute-phase protein synthesis by rodent hepatocytes in vitro.. Immunology. 60:203-207. 1987
- Unique characteristics of local responses in host resistance to mucosal parasitic infections. Veterinary Parasitology. 20:175-194. 1986
- Bleeding time in hemophilia a: Potential mechanisms for prolongation. Journal of Pediatrics. 108:215-218. 1986
- Interleukin-1 and interleukin-2 production in resistant and susceptible inbred mice infected with Trypanosoma congolense.. Immunology. 57:291-296. 1986
- The concentration of IgG in the serum is a major determinant of Fc- dependent reticuloendothelial function. Blood. 66:490-495. 1985
- IgA-mediated phagocytosis by mouse alveolar macrophages.. American Journal of Respiratory and Critical Care Medicine. 132:82-85. 1985
- Activation of alveolar macrophages following infection with the parasitic nematode Nippostrongylus brasiliensis.. Immunology. 54:581-588. 1985
- In vivo initiation of unstimulated in vitro interleukin-1 release by alveolar macrophages.. American Journal of Respiratory and Critical Care Medicine. 131:326-330. 1985
- Synthesis of alpha 1-protease inhibitor by resident and activated mouse alveolar macrophages.. American Journal of Respiratory and Critical Care Medicine. 131:321-325. 1985
- A simple bioassay for monocyte-derived hepatocyte stimulating factor: Increased synthesis of α2-macroglobulin and reduced synthesis of albumin by cultured rat hepatocytes. Journal of Immunological Methods. 76:317-327. 1985
- Acute Phase Response in Infectious Disease. Survey and synthesis of pathology research. 4:126-151. 1985
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- Multinucleate giant cells in murine and rat lungs during Nippostrongylus brasiliensis infections. A study of the kinetics of the response in vivo, cytochemistry, IgG‐ and C3‐mediated functions. Parasite Immunology. 7:11-18. 1985
- Synthesis and turnover of prothrombin during experimental inflammation in rats.. International Journal of Experimental Pathology. 65:691-700. 1984
- The acute-phase response of cultured rat hepatocytes. System characterization and the effect of human cytokines. Biochemical Journal. 224:505-514. 1984
- ANGIOIMMUNOBLASTIC LYMPHADENOPATHY ASSOCIATED WITH RESERPINE. The Lancet. 324:820-821. 1984
- The acute phase response in parasite infection. Nippostrongylus brasiliensis in the mouse.. Immunology. 52:733-741. 1984
- The relationship among platelet-associated IgG, platelet lifespan, and reticuloendothelial cell function. Blood. 63:1434-1438. 1984
- Broncho‐alveolar leucocyte responses during primary and secondary Nippostrongylus brasiliensis infection in the rat. Parasite Immunology. 6:191-201. 1984
- Two populations of prelysosomal structures transporting asialoglycoproteins in rat liver.. Proceedings of the National Academy of Sciences of the United States of America. 81:2995-2999. 1984
- Complement-dependent killing of Nippostrongylus brasiliensis infective larvae by rat alveolar macrophages.. Clinical and Experimental Immunology. 55:149-156. 1984
- Human monocyte-derived and epidermal cell-derived cytokines stimulate cultured rat hepatocytes to increased synthesis of acute-phase proteins. The FASEB Journal. 43. 1984
- Sensitivity to suppression of cytotoxic T cell generation by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is dependent on the Ah genotype of the murine host. Toxicology and Applied Pharmacology. 72:169-176. 1984
- The expression of IgA Fc receptors on murine eosinophils. The FASEB Journal. 43. 1984
- Fc receptors for IgA and other immunoglobulins on resident and activated alveolar macrophages. Molecular Immunology. 20:1029-1037. 1983
- Cellular and genetic basis for suppression of cytotoxic T cell generation by haloaromatic hydrocarbons. Immunopharmacology. 6:143-153. 1983
- Lack of specificity of the C3-opsonized zymosan reagent for the assay of membrane complement receptors. Journal of Immunological Methods. 61:253-257. 1983
- Detection of human fetal fibrinogen in umbilical cord plasma by parallel assays of immunoreactive and thrombin-clottable protein.. Annals of Clinical Research. 15:104-108. 1983
- Immune-mediated thrombocytopenia of malaria.. Journal of Clinical Investigation. 71:832-836. 1983
- The Measurement of Plateiet-Associated IgG Using an Immunoradiometric Assay. Journal of Immunoassay and Immunochemistry. 4:65-82. 1983
- Mucosal mast cells. I. Isolation and functional characteristics of rat intestinal mast cells.. Journal of Immunology. 128:2475-2480. 1982
- Mucosal mast cells. II. Effects of anti-allergic compounds on histamine secretion by isolated intestinal mast cells.. Journal of Immunology. 128:2481-2486. 1982
- Pulmonary Function Abnormalities in Patients with Inflammatory Bowel Disease. QJM - Monthly Journal of the Association of Physicians. 51:241-250. 1982
- Enhanced Suppressor Cell Activity as a Mechanism of Immunosuppression by 2,3,7,8-Tetrachlorodibenzo-p-dioxin. Experimental Biology and Medicine. 168:290-299. 1981
- Ontogeny and tissue distribution of alpha-1-antitrypsin of the mouse. Biochimica et Biophysica Acta: international journal of biochemistry and biophysics. 662:15-21. 1981
- The development and application of a serum assay for platelet-bindable IgG (S-PBIgG).. Translational Research. 98:272-279. 1981
- Hypersensitivity to tobacco glycoprotein in human peripheral vascular disease.. Annals of Allergy, Asthma and Immunology. 47:8-13. 1981
- Selective suppression of cytotoxic T cell (CTL) generation by halogenated aromatic hydrocarbons. The FASEB Journal. 40. 1981
- Immunohistochemical localization of alpha 1-antitrypsin in normal mouse liver and pancreas.. American Journal of Pathology. 101:723-736. 1980
- Ontogeny of mouse and rat antithrombin III. Thrombosis Research. 20:417-424. 1980
- Selection of medical students. Medical Education. 14:241-242. 1980
- Radioimmunoassay for Dog Myoglobin. Journal of Immunoassay and Immunochemistry. 1:251-269. 1980
- Solid-phase radioimmunoassay with protein-A-bearing Staphylococcus aureus cells used to assay a protein (ferritin) and a hapten (digoxin).. Clinical Chemistry. 26:37-40. 1980
- Some immunochemical properties of bovine and rat rhodanese.. Folia Biologica. 28:121-126. 1980
- Process for Selection of Medical Students at McMaster University. Programmed Learning and Educational Technology. 16:303-307. 1979
- Leprosy's Footprints in Bone Marrow. New England Journal of Medicine. 301:272-273. 1979
- Platelet-Associated IgG in Septicemia. New England Journal of Medicine. 301:271-272. 1979
- Motilin, human pancreatic polypeptide (HPP) and gastrin plasma concentrations in fasting subjects. Clinical Biochemistry. 12:109-117. 1979
- Hemoglobin ontogeny during normal mouse fetal development.. Proceedings of the National Academy of Sciences of the United States of America. 76:2853-2857. 1979
- Elevated Platelet-Associated IgG in the Thrombocytopenia of Septicemia. New England Journal of Medicine. 300:760-764. 1979
- Nephelometric Activity as a Criterion of Adequate Antisera for Use in Immunofluorescence. International Archives of Allergy and Applied Immunology. 60:186-194. 1979
- The direct assay for platelet-associated IgG (PAIgG): lack of association between antibody level and platelet size. Blood. 53:73-80. 1979
- EFFECTS OF ACTIVE IMMUNIZATION OF FEMALE RABBITS AGAINST TESTOSTERONE. Journal of Endocrinology. 79:339-347. 1978
- Progress towards international reference standards for human serum proteins. Journal of Biological Standardization. 6:133-158. 1978
- Synthesis of antithrombin III and alpha-1-antitrypsin by the perfused rat liver. Biochimica et Biophysica Acta: international journal of biochemistry and biophysics. 539:496-504. 1978
- The Structures of Some Peptides from Bee Venom. The FEBS Journal. 83:405-410. 1978
- The effect of thrombocytopenia on experimental arteriosclerotic lesion formation in rabbits. Smooth muscle cell proliferation and re-endothelialization.. Journal of Clinical Investigation. 60:1191-1201. 1977
- A Radioimmunoassay for Serum Ferritin. Clinical Chemistry. 23:683-689. 1977
- An approach to immunotherapy using antibody to IgE in mast cell leukemia. Cancer. 37:693-696. 1976
- Inhibition of Injury Induced Thromboatherosclerotic Lesions by Anti-Platelet Serum in Rabbits. Thrombosis and Haemostasis. 35:070-081. 1976
- SOCIAL-WORK AS TAUGHT. New society. 35:488-491. 1976
- The Peptide Components of Bee Venom. The FEBS Journal. 61:369-376. 1976
- Thermodynamic aspects of some radioassays.. Clinical Chemistry. 22:70-73. 1976
- Pseudothrombocytopenia Due to Platelet Aggregation and Degranulation in Blood Collected in EDTA. European Journal of Haematology. 15:161-170. 1975
- Alteration of the HL-A Antigenic site in Situ. Immunological Investigations. 4:465-476. 1975
- Automated nephelometric inhibition immunoassay of digoxin and morphine. The FASEB Journal. 34. 1975
- Synthesis of IgG, IgA, IgM by Chicken Tissues: Immunofluorescent and 14C Amino Acid Incorporation Studies. Journal of Immunology. 111:1112-1118. 1973
- Von Willebrand's Syndrome Presenting as an Acquired Bleeding Disorder in Association With a Monoclonal Gammopathy. Blood. 42:429-436. 1973
- Late cutaneous allergic responses in isolated IgE-dependent reactions. Journal of Allergy and Clinical Immunology. 52:38-46. 1973
- Purification and properties of dihydrofolate reductase from cultured mammalian cells. Biochemical Journal. 133:349-356. 1973
- Chicken γA: Physicochemical and Immunochemical Characteristics. Journal of Immunology. 110:524-533. 1973
- Chicken Immunoglobulin Resembling γA. Journal of Immunology. 109:403-406. 1972
- Multiple enzyme forms from protein-bromphenol blue interaction during gel electrophoresis. Analytical Biochemistry. 46:433-437. 1972
- Purification of tetrahydrofolate dehydrogenase by affinity chromatography. Biochimica et Biophysica Acta: international journal of biochemistry and biophysics. 268:35-40. 1972
- STABILIZATION OF DIHYDROFOLATE REDUCTASE BY INHIBITORS IN VIVO AND IN VITRO*. Annals of the New York Academy of Sciences. 186:187-205. 1971
- The Dissociation into Subunits of Aspartate Aminotransferase from Pig Heart Muscle. The FEBS Journal. 6:507-513. 1968
- Acid Phosphatases. Nature. 208:382-383. 1965