Journal article
Mutagenic reaction products of aqueous chlorination of catechol
Abstract
Aqueous chlorination of catechol (4 and 8 mM) at varying reagent ratio has been shown to produce high mutagenicity with the Ames Salmonella strain TA100. The mutagenicity peaks at 3 equivalents of chlorine per mole of catechol. But the mutagens are unstable in neutral and alkaline solutions. Substituted catechols produce less mutagenic solutions than catechol on aqueous chlorination. If the chlorine is replaced with equivalent chlorine dioxide …
Authors
Nazar MA; Rapson WH; Brook MA; May S; Tarhanen J
Journal
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, Vol. 89, No. 1, pp. 45–55
Publisher
Elsevier
Publication Date
5 1981
DOI
10.1016/0165-1218(81)90129-4
ISSN
0027-5107